Flavor ingredient regulatory record
Calcium Acetate
Calcium Acetate is an ester, FEMA GRAS under FEMA number 2228 (CAS 62-54-4). Its odor is sLIGHT ODOR OF ACETIC ACID.
- FEMA
- 2228
- CAS
- 62-54-4
- Formula
- C4H6CaO4
- EC
- 200-540-9
GRAS status: FEMA GRAS, publication 3. Recorded by FDA in the Substances Added to Food inventory under CAS 62-54-4.
Structure
Identity
Also known as: Acetic acid, calcium salt (2:1), Acetic acid, calcium salt, Brown acetate, Calcium diacetate, Gray acetate, Lime acetate, Lime pyrolignite, Sorbo-Calcion, Teltozan, Sanopan, PhosLo, Royen.
Can Calcium Acetate be labeled natural?
Calcium Acetate occurs in nature, so the label depends on the route: Calcium Acetate won from a natural source by a physical, enzymatic or microbiological process is natural flavor in the United States, and synthesized Calcium Acetate is artificial. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic Calcium Acetate identical-to-natural.
- United States
- Natural or artificial, by process
- European Union and UK
- Natural only from natural material
- Mercosur and Mexico
- Natural or identical-to-natural
How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.
Regulatory status, with citations
United States
Calcium Acetate is FEMA GRAS under FEMA number 2228. It is cited in the Code of Federal Regulations at 21 CFR 184.1185.
European Union and United Kingdom
No EU FL number is on file for Calcium Acetate. That is not a finding either way. The Union List covers defined flavouring substances, so natural complex materials are handled as flavouring preparations under Parts B to F and never receive a number, and substances used as additives sit under Regulation 1333/2008 instead. Confirm the position before EU or UK use.
JECFA (WHO / FAO)
Calcium Acetate has not been evaluated by JECFA as a flavouring agent, or no evaluation is on file.
Other US flags
Not on the California Proposition 65 list.
TSCA Inventory status
A flavor ingredient is also an industrial chemical. Calcium Acetate appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 62-54-4, where EPA names it Acetic acid, calcium salt (2:1).
Active in US commerce
EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.
EPA publishes no regulatory flags on this listing. What the flags mean.
From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.
Odor and taste
Odor: SLIGHT ODOR OF ACETIC ACID.
Where it is used
Typical applications for Calcium Acetate are not on file yet.
Calcium Acetate FAQ
Is Calcium Acetate on the FEMA GRAS list?
It is. FEMA number 2228 covers Calcium Acetate. It is also codified at 21 CFR 184.1185.
What is the FEMA number for Calcium Acetate?
The FEMA number for Calcium Acetate is 2228 and its CAS registry number is 62-54-4.
Is Calcium Acetate natural or artificial?
Since Calcium Acetate is found in nature, US labeling follows how it was obtained: natural flavor from a natural source and a natural process, artificial when Calcium Acetate is synthesized. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic Calcium Acetate identical-to-natural.
What is Calcium Acetate used for?
Calcium Acetate is described as sLIGHT ODOR OF ACETIC ACID.
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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as CALCIUM ACETATE under CAS 62-54-4 and carries its FEMA number and its 21 CFR citations. The inventory is searchable at FDA. FDA records its technical effect as color or coloring adjunct, firming agent, flavoring agent or adjuvant, ph control agent, processing aid, sequestrant, stabilizer or thickener, texturizer.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.