Insights

AI in the flavor & fragrance industry

Working notes, technical takes, and field reports from building Ambrose.

How to File a GRAS Notification with the FDA

July 18, 2026 · By Will Pemble

A step-by-step overview of the FDA's voluntary GRAS Notification program: what a notice contains, how the seven parts fit together, and how it is submitted.

#gras-notification #fda #regulatory #compliance #gras-notice

Read →

21 CFR 101.22: Natural vs Artificial Flavor

July 18, 2026 · By Will Pemble

Under 21 CFR 101.22 the difference is origin, not chemistry. What (a)(3), (i) and (j) each require, and why (j) is not about flavor at all.

#natural-flavor #artificial-flavor #21-cfr-101-22 #labeling #regulatory

Read →

What Is FEMA GRAS? Flavor Ingredient Safety

July 18, 2026 · By Will Pemble

How the FEMA Expert Panel reaches a GRAS conclusion on a flavor ingredient, what a FEMA number tells you, and why that is not the same as FDA approval.

#fema-gras #regulatory #compliance #flavor-ingredients #fda

Read →

What Is an AI Flavor Formulator?

July 18, 2026 · By Will Pemble

A plain-language guide to AI flavor formulators: what they do, how a real flavor-chemistry engine differs from a chatbot, and how to tell the two apart.

#ai #flavor-formulation #flavor-chemistry #r-and-d #aroma-chemicals

Read →

How much does regulatory and labeling work actually cost you?

July 14, 2026 · By Will Pemble

What your current stack costs in dollars and chemist-weeks, with an interactive calculator so you can see it for your own portfolio.

#r-and-d #formulation #regulatory #labeling #cost-benchmarks #flavor #fragrance #brewery #coffee-tea #personal-care

Read →

Get the next one in your inbox

Twice-monthly. AI in the flavor and fragrance industry. No fluff.