Flavor ingredient regulatory record
Digeranyl ether
Digeranyl ether is an ether in the fruity family, FEMA GRAS under FEMA number 4664 (CAS 31147-36-1). Its odor is sweet, fruity, floral, herbal, estery.
- FEMA
- 4664
- CAS
- 31147-36-1
- JECFA
- 2142
- EU FL
- 03.024
- Formula
- C20H34O
- EC
- 250-486-5
GRAS status: FEMA GRAS, publication 24. Recorded by FDA in the Substances Added to Food inventory under CAS 31147-36-1.
Structure
Identity
Also known as: 2,6-Octadiene, 1,1′-oxybis[3,7-dimethyl-, (2E,6E)-, Ether, bis(3,7-dimethyl-2,6-octadienyl), (E,E)-, 2,6-Octadiene, 1,1′-oxybis[3,7-dimethyl-, (E,E)-, (2E,6E)-1,1′-Oxybis[3,7-dimethyl-2,6-octadiene], 2,6-octadiene, 1,1'-oxybis(3,7-dimethyl-, (2e,6e)-, 2,6-octadiene, 1,1'-oxybis[3,7-dimethyl-, (2e,6e)-, 2,6-octadiene, 1,1'-oxybis(3,7-dimethyl-, (e,e)-, ether, bis(3,7-dimethyl-2,6-octadienyl), (e,e)-, (2e,6e)-1,1'-oxybis(3,7-dimethyl-2,6-octadiene), (2e,6e)-1,1'-oxybis[3,7-dimethyl-2,6-octadiene], (e,e)-geranyl neryl ether, 1,1"-oxybis(3,7-dimethyl-(2e)-octadiene).
Can Digeranyl ether be labeled natural?
Nature occurrence: Not yet found in nature (provisional).
Nature occurrence has not been settled for this substance, so the natural or artificial class is not stated here. The FEMA GRAS status does not depend on it.
Regulatory status, with citations
United States
Digeranyl ether is FEMA GRAS under FEMA number 4664. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
Listed on the Union List of flavouring substances as FL 03.024, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.
JECFA (WHO / FAO)
JECFA number 2142.
Other US flags
Not on the California Proposition 65 list.
TSCA Inventory status
A flavor ingredient is also an industrial chemical. Digeranyl ether appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 31147-36-1, where EPA names it 2,6-Octadiene, 1,1'-oxybis[3,7-dimethyl-, (2E,6E)-.
Inactive in US commerce
EPA designates this substance inactive, so a Notice of Activity Form B is required before anyone manufactures or processes it again. Being FEMA GRAS does not change that. What active and inactive mean.
EPA publishes no regulatory flags on this listing. What the flags mean.
From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.
Odor and taste
Odor: Sweet, fruity, floral, herbal, estery.
Where it is used
Digeranyl ether is used in beverage, confection, flavoring, bakery and desserts, typically as a fruity note.
Structurally similar flavor ingredients
Flavor ingredients with a GRAS determination closest to Digeranyl ether by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.
| Material | FEMA | Similarity | Occurrence |
|---|---|---|---|
| Farnesol | 2478 | 79% | In nature |
| 3,7,11-Trimethyl-2,6,10-dodecatrienal | 4019 | 79% | In nature |
| 2,6,10-Trimethyl-2,6,10-pentadecatrien-14-one | 3442 | 78% | In nature |
| Neryl isovalerate | 2778 | 78% | In nature |
| (E,Z)-Phytyl acetate | 4197 | 78% | In nature |
More ethers in this index
Benzyl butyl ether · 1,1-Dimethoxyethane · sec-Butyl ethyl ether · 2,4-Dimethyl-1,3-dioxolane · o-Methylanisole · Hydroquinone monoethyl ether
Digeranyl ether FAQ
Is digeranyl ether on the FEMA GRAS list?
It is. FEMA number 4664 covers digeranyl ether. It is also codified at 21 CFR 172.515.
What is the FEMA number for digeranyl ether?
The FEMA number for digeranyl ether is 4664 and its CAS registry number is 31147-36-1. FEMA files it in the fruity flavor category.
Is digeranyl ether approved in the EU?
Digeranyl ether is on the EU Union List of flavouring substances as FL 03.024 (Annex I Part A) under Regulation 1334/2008.
Has JECFA evaluated digeranyl ether?
Yes. JECFA number 2142.
What is digeranyl ether used for?
Digeranyl ether is described as sweet, fruity, floral, herbal, estery. It shows up in beverage, confection, flavoring, bakery and desserts.
Ingredient lookup
Check an ingredient
Start typing to search the ingredient corpus.
Or browse every ingredient page, A to Z.
Guides: What Is FEMA GRAS? · Natural vs artificial · Filing a GRAS notification
Check Digeranyl ether in a formula
Screened against FEMA GRAS, 21 CFR and EU rules as you build. Free to start.
Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as DIGERANYL ETHER under CAS 31147-36-1 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.