Flavor ingredient regulatory record
Isopentylamine
Isopentylamine is an amine in the fruity family, FEMA GRAS under FEMA number 3219 (CAS 107-85-7). Its odor is sweet, fruity, banana, floral, nutty.
- FEMA
- 3219
- CAS
- 107-85-7
- JECFA
- 1587
- EU FL
- 11.001
- Formula
- C5H13N
- EC
- 203-526-0
GRAS status: FEMA GRAS, publication 4. Recorded by FDA in the Substances Added to Food inventory under CAS 107-85-7.
Structure
Identity
Also known as: 1-Butanamine, 3-methyl-, Propylamine, 3,3-dimethyl-, 3-Methyl-1-butanamine, Isoamylamine, Leucamine, 3-Methylbutylamine, γ-Isoamylamine, Monoisoamylamine, 1-Amino-3-methylbutane, 3-Methylbutanamine, Isovalerylamine, Monoisopentylamine.
Can Isopentylamine be labeled natural?
The process decides for isopentylamine. It occurs in nature, so a natural-source, natural-process material is natural flavor in the US and synthetic isopentylamine is artificial. The EU and UK grant the natural claim only to that natural route; Mercosur and Mexico call synthetic material identical-to-natural.
- United States
- Natural or artificial, by process
- European Union and UK
- Natural only from natural material
- Mercosur and Mexico
- Natural or identical-to-natural
How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.
Regulatory status, with citations
United States
Isopentylamine is FEMA GRAS under FEMA number 3219. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
Listed on the Union List of flavouring substances as FL 11.001, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.
JECFA (WHO / FAO)
JECFA number 1587, evaluated at the 65th meeting in 2005. No safety concern at current levels of intake when used as a flavouring agent.
Other US flags
Not on the California Proposition 65 list.
TSCA Inventory status
A flavor ingredient is also an industrial chemical. Isopentylamine appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 107-85-7, where EPA names it 1-Butanamine, 3-methyl-.
Active in US commerce
EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.
EPA publishes no regulatory flags on this listing. What the flags mean.
From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.
Odor and taste
Odor: Sweet, fruity, banana, floral, nutty.
Where it is used
Isopentylamine is used in beverage, confection, flavoring agent and snacks, typically as a fruity note.
Structurally similar flavor ingredients
Flavor ingredients with a GRAS determination closest to Isopentylamine by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.
| Material | FEMA | Similarity | Occurrence |
|---|---|---|---|
| Butylamine | 3130 | 95% | In nature |
| 2-Methylbutylamine | 4241 | 94% | Not determined |
| 2-Pentanol | 3316 | 90% | In nature |
| Isobutylamine | 4239 | 85% | In nature |
| Pentylamine | 4242 | 85% | In nature |
More amines in this index
Isopentylidene isopentylamine · Pentylamine · Hexylamine · 2-Methylbutylamine · Phenethylamine · Tripropylamine
Isopentylamine FAQ
Is isopentylamine FEMA GRAS?
Yes. The FEMA Expert Panel lists isopentylamine as GRAS under FEMA number 3219. The Code of Federal Regulations lists it at 21 CFR 172.515.
What are the FEMA and CAS numbers for isopentylamine?
Isopentylamine is FEMA 3219, CAS 107-85-7. Its flavor category is fruity.
How is isopentylamine described, and where does it show up?
Flavorists describe isopentylamine as sweet, fruity, banana, floral, nutty. It is used in beverage, confection, flavoring agent and snacks.
What did JECFA conclude about isopentylamine?
JECFA evaluated isopentylamine at the 65th meeting in 2005 under JECFA number 1587. The panel concluded: No safety concern at current levels of intake when used as a flavouring agent.
Is isopentylamine on the EU Union List?
Yes. FL 11.001 is the Union List entry for isopentylamine, annex I Part A, under Regulation 1334/2008, and the UK keeps the same list.
Does isopentylamine count as natural in the US and the EU?
Nature makes isopentylamine, which is why the US label turns on process. A natural route gives natural flavor; synthesis gives artificial isopentylamine, same molecule. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.
Ingredient lookup
Check an ingredient
Start typing to search the ingredient corpus.
Or browse every ingredient page, A to Z.
Guides: What Is FEMA GRAS? · Natural vs artificial · Filing a GRAS notification
Check Isopentylamine in a formula
Screened against FEMA GRAS, 21 CFR and EU rules as you build. Free to start.
Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as ISOPENTYLAMINE under CAS 107-85-7 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.