Flavor ingredient regulatory record

Licorice Root

Licorice Root is a natural complex flavoring material, FEMA GRAS under FEMA number 2630 (CAS 68916-91-6).

FEMA
2630
CAS
68916-91-6
EC
272-837-1

GRAS status: FEMA GRAS, publication 3. Recorded by FDA in the Substances Added to Food inventory under CAS 977004-31-1.

Structure

Material

Licorice Root is a natural complex material rather than a single molecule, so it has no one structure. FEMA lists it as LICORICE ROOT (GLYCYRRHIZA GLABRA L.).

Identity

CAS number 68916-91-6
FEMA number 2630
EC number 272-837-1

Also known as: Pharmaceutical natural products, licorice, Licorice, ext., Licorice extract, Glycyrrhiza extract, Licorice root extract, Licorice, Licorice (pharmaceutical), Natural products, pharmaceutical, licorice, FM 100, FM 100 (extract), LX 103, Kanzoh.

Can Licorice Root be labeled natural?

Made from natural raw material, Licorice Root carries the natural claim in the United States, in the EU and UK under Regulation 1334/2008, and in Mercosur and Mexico.

United States
Natural flavor
European Union and UK
Natural flavouring
Mercosur and Mexico
Natural

How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.

Regulatory status, with citations

United States

Licorice Root is FEMA GRAS under FEMA number 2630. It is cited in the Code of Federal Regulations at 21 CFR 184.1408.

21 CFR 184.1408

European Union and United Kingdom

No EU FL number is on file for Licorice Root. That is not a finding either way. The Union List covers defined flavouring substances, so natural complex materials are handled as flavouring preparations under Parts B to F and never receive a number, and substances used as additives sit under Regulation 1333/2008 instead. Confirm the position before EU or UK use.

JECFA (WHO / FAO)

Licorice Root has not been evaluated by JECFA as a flavouring agent, or no evaluation is on file.

Other US flags

Not on the California Proposition 65 list.

Odor and taste

Taste: Although without interest for perfumery, this product is one of the most important of the non- fruity flavor materials from nature. One of the more practical reasons as to why licorice finds.

Where it is used

Typical applications for Licorice Root are not on file yet.

Licorice Root FAQ

Is Licorice Root on the FEMA GRAS list?

It is. FEMA number 2630 covers Licorice Root. It is also codified at 21 CFR 184.1408.

What is the FEMA number for Licorice Root?

The FEMA number for Licorice Root is 2630 and its CAS registry number is 68916-91-6.

Is Licorice Root natural or artificial?

Licorice Root is a preparation from natural raw material, so it is natural flavor in the United States, natural flavouring in the EU and UK, and natural in Mercosur and Mexico.

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Guides: What Is FEMA GRAS? · Natural vs artificial · Filing a GRAS notification

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as LICORICE (GLYCYRRHIZA SPP.) under CAS 977004-31-1 and carries its FEMA number and its 21 CFR citations. The inventory is searchable at FDA. FDA records its technical effect as flavor enhancer, flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.