Flavor ingredient regulatory record
Mono- and diglycerides of fatty acids
Mono- and diglycerides of fatty acids is a natural complex flavoring material in the dairy family, FEMA GRAS under FEMA number 4186 (CAS 67701-32-0). Its odor is creamy, fatty, mild, neutral.
- FEMA
- 4186
- CAS
- 67701-32-0
GRAS status: FEMA GRAS, publication 22. Recorded by FDA in the Substances Added to Food inventory under CAS 67254-73-3.
Structure
Material
Mono- and diglycerides of fatty acids is a natural complex material rather than a single molecule, so it has no one structure. FEMA lists it as Mono- and diglycerides of fatty acids.
Identity
Also known as: Glycerides, C14-18 and C16-18-unsaturated monoglycerides and diglycerides, Glycerides, C14-18 and C16-18-unsatd. mono- and di-, Glycerides, C14-18 and C16-18-unsatd. monoglycerides and diglycerides, Diglycerides, C14-18 and C16-18-unsatd. monoglycerides and diglycerides, Monoglycerides, C14-18 and C16-18-unsatd. monoglycerides and diglycerides, Diglycerides, C14-18 and C16-18-unsaturated monoglycerides and diglycerides, Monoglycerides, C14-18 and C16-18-unsaturated monoglycerides and diglycerides, Alphadim 90NLK.
Can Mono- and diglycerides of fatty acids be labeled natural?
Nature occurrence: Not yet found in nature (provisional).
Nature occurrence has not been settled for this substance, so the natural or artificial class is not stated here. The FEMA GRAS status does not depend on it.
Regulatory status, with citations
United States
Mono- and diglycerides of fatty acids is FEMA GRAS under FEMA number 4186. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
No EU FL number is on file for Mono- and diglycerides of fatty acids. That is not a finding either way. The Union List covers defined flavouring substances, so natural complex materials are handled as flavouring preparations under Parts B to F and never receive a number, and substances used as additives sit under Regulation 1333/2008 instead. Confirm the position before EU or UK use.
JECFA (WHO / FAO)
Mono- and diglycerides of fatty acids has not been evaluated by JECFA as a flavouring agent, or no evaluation is on file.
Other US flags
Not on the California Proposition 65 list.
TSCA Inventory status
A flavor ingredient is also an industrial chemical. Mono- and diglycerides of fatty acids appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 67701-32-0, where EPA names it Glycerides, C14-18 and C16-18-unsatd. mono- and di-.
Active in US commerce
EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.
EPA regulatory flags
| Flag | EPA definition | What it obliges |
|---|---|---|
| UVCB | The presence of "UVCB" indicates the substance is a Class 2 substance within the UVCB group, i.e. those with "unknown" or "variable composition," "complex reaction products" and "biological materials." | Care with identity. A UVCB has no definite molecular formula, so its identity rests on the process and the feedstock. Two suppliers can ship materially different material under one CAS number. |
From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.
Odor and taste
Odor: Creamy, fatty, mild, neutral.
Taste: Mild, creamy, slightly sweet.
Where it is used
Mono- and diglycerides of fatty acids is used in baked goods, dairy, confection, margarine and emulsifier, typically as a dairy note.
More esters in this index
Tributyrin · Glyceryl monostearate · Diacetyl tartaric acid esters of mono- and diglycerides · Glucose pentaacetate · Propyl acetate · Ethyl 3-hydroxybutyrate
Mono- and diglycerides of fatty acids FAQ
Does Mono- and diglycerides of fatty acids have FEMA GRAS status?
Mono- and diglycerides of fatty acids holds FEMA GRAS status under FEMA number 4186. It is also codified at 21 CFR 172.515.
How do I cite Mono- and diglycerides of fatty acids by FEMA or CAS number?
Cite Mono- and diglycerides of fatty acids as FEMA 4186 or CAS 67701-32-0; both point to the same entry. FEMA files it in the dairy flavor category.
What does Mono- and diglycerides of fatty acids smell and taste like, and where is it used?
The odor of Mono- and diglycerides of fatty acids is creamy, fatty, mild, neutral. On the palate it is mild, creamy, slightly sweet. Typical uses are baked goods, dairy, confection, margarine and emulsifier.
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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as MONO- AND DIGLYCERIDES under CAS 67254-73-3 and carries its FEMA number and its 21 CFR citations. The inventory is searchable at FDA. FDA records its technical effect as emulsifier or emulsifier salt, flavor enhancer, flavoring agent or adjuvant, lubricant or release agent, masticatory substance, stabilizer or thickener, surface-active agent, texturizer.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.