Flavor ingredient regulatory record
Propyleneglycol mono-2-methylbutyrate
Propyleneglycol mono-2-methylbutyrate is an ester in the fruity family, FEMA GRAS under FEMA number 4467 (CAS 923593-56-0). Its odor is sweet, fruity, berry, estery, floral.
- FEMA
- 4467
- CAS
- 923593-56-0
- JECFA
- 1981
GRAS status: FEMA GRAS, publication 24. Recorded by FDA in the Substances Added to Food inventory under CAS 977187-82-8.
Structure
Under review
The structure for Propyleneglycol mono-2-methylbutyrate is still under identity review, so no drawing is shown until the record is confirmed.
Identity
Also known as: 2-hydroxypropyl 2-methylbutanoate, propylene glycol 1-(2-methylbutyrate), 1-propylene glycol 2'-methylbutyrate, 1-propylene glycol 2'-methylbutanoate, butanoic acid, 2-methyl-, 2-hydroxypropyl ester, (+-)-2-hydroxypropyl 2-methylbutanoate, 2-hydroxypropyl 2-methylbutanoate, (+-)-, (+/-)-2-hydroxypropyl 2-methylbutanoate, 2-hydroxypropyl 2-methylbutanoate, (+/-)-.
Can Propyleneglycol mono-2-methylbutyrate be labeled natural?
Nature occurrence: Not yet found in nature (provisional).
Nature occurrence has not been settled for this substance, so the natural or artificial class is not stated here. The FEMA GRAS status does not depend on it.
Regulatory status, with citations
United States
Propyleneglycol mono-2-methylbutyrate is FEMA GRAS under FEMA number 4467. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
No EU FL number is on file for Propyleneglycol mono-2-methylbutyrate. That is not a finding either way. The Union List covers defined flavouring substances, so natural complex materials are handled as flavouring preparations under Parts B to F and never receive a number, and substances used as additives sit under Regulation 1333/2008 instead. Confirm the position before EU or UK use.
JECFA (WHO / FAO)
JECFA number 1981, evaluated at the 73rd meeting in 2010. No safety concern at current levels of intake when used as a flavouring agent.
Other US flags
Not on the California Proposition 65 list.
Odor and taste
Odor: Sweet, fruity, berry, estery, floral.
Where it is used
Propyleneglycol mono-2-methylbutyrate is used in beverage, confection, fruit flavors, bakery and desserts, typically as a fruity note.
Structurally similar flavor ingredients
Flavor ingredients with a GRAS determination closest to Propyleneglycol mono-2-methylbutyrate by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.
| Material | FEMA | Similarity | Occurrence |
|---|---|---|---|
| Propyleneglycol monobutyrate | 4488 | 93% | Not determined |
More esters in this index
Guaiacol butyrate · Isoamyl nonanoate · Isobutyl salicylate · Neryl isovalerate · alpha-Methylphenethyl butyrate · 2-Acetoxy-3-butanone
Propyleneglycol mono-2-methylbutyrate FAQ
Is propyleneglycol mono-2-methylbutyrate FEMA GRAS?
Yes. The FEMA Expert Panel lists propyleneglycol mono-2-methylbutyrate as GRAS under FEMA number 4467. The Code of Federal Regulations lists it at 21 CFR 172.515.
What are the FEMA and CAS numbers for propyleneglycol mono-2-methylbutyrate?
Propyleneglycol mono-2-methylbutyrate is FEMA 4467, CAS 923593-56-0. Its flavor category is fruity.
How is propyleneglycol mono-2-methylbutyrate described, and where does it show up?
Flavorists describe propyleneglycol mono-2-methylbutyrate as sweet, fruity, berry, estery, floral. It is used in beverage, confection, fruit flavors, bakery and desserts.
What did JECFA conclude about propyleneglycol mono-2-methylbutyrate?
JECFA evaluated propyleneglycol mono-2-methylbutyrate at the 73rd meeting in 2010 under JECFA number 1981. The panel concluded: No safety concern at current levels of intake when used as a flavouring agent.
Is propyleneglycol mono-2-methylbutyrate approved in the EU?
No EU FL number is on file for propyleneglycol mono-2-methylbutyrate. It has a JECFA evaluation (JECFA 1981), which the EU list draws on, but the Union List entry itself should be confirmed before EU use.
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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as PROPYLENEGLYCOL MONO-2-METHYLBUTYRATE under CAS 977187-82-8 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.