Flavor ingredient regulatory record
Trehalose, dihydrate
Trehalose, dihydrate is a disaccharide in the sweet family, FEMA GRAS under FEMA number 4600 (CAS 6138-23-4). Its odor is sweet, mild, subtle, neutral.
- FEMA
- 4600
- CAS
- 6138-23-4
- Formula
- C12H26O13
GRAS status: FEMA GRAS, publication 24. Recorded by FDA in the Substances Added to Food inventory under CAS 6138-23-4.
Structure
Identity
Also known as: α-D-Glucopyranoside, α-D-glucopyranosyl, hydrate (1:2), α-D-Glucopyranoside, α-D-glucopyranosyl, dihydrate, α-D-Glucopyranosyl α-D-glucopyranoside dihydrate, α,α-Trehalose dihydrate, D-(+)-Trehalose dihydrate, D-Trehalose dihydrate, alpha-d-glucopyranoside, alpha-d-glucopyranosyl, dihydrate, .alpha.-d-glucopyranoside, .alpha.-d-glucopyranosyl, dihydrate, d-(+)-trehalose dihydrate, trehalose dihydrate, d-trehalose dihydrate, alpha,alpha-trehalose dihydrate.
Can Trehalose, dihydrate be labeled natural?
Nature occurrence: Not yet found in nature (provisional).
Nature occurrence has not been settled for this substance, so the natural or artificial class is not stated here. The FEMA GRAS status does not depend on it.
Regulatory status, with citations
United States
Trehalose, dihydrate is FEMA GRAS under FEMA number 4600. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
No EU FL number is on file for Trehalose, dihydrate. That is not a finding either way. The Union List covers defined flavouring substances, so natural complex materials are handled as flavouring preparations under Parts B to F and never receive a number, and substances used as additives sit under Regulation 1333/2008 instead. Confirm the position before EU or UK use.
JECFA (WHO / FAO)
Trehalose, dihydrate has not been evaluated by JECFA as a flavouring agent, or no evaluation is on file.
Other US flags
Not on the California Proposition 65 list.
Odor and taste
Odor: Sweet, mild, subtle, neutral.
Taste: Sweet, pleasant, smooth.
Where it is used
Trehalose, dihydrate is used in beverage, confection, baked goods and snacks, typically as a sweet note.
Trehalose, dihydrate FAQ
Does Trehalose, dihydrate have FEMA GRAS status?
Trehalose, dihydrate holds FEMA GRAS status under FEMA number 4600. It is also codified at 21 CFR 172.515.
How do I cite Trehalose, dihydrate by FEMA or CAS number?
Cite Trehalose, dihydrate as FEMA 4600 or CAS 6138-23-4; both point to the same entry. FEMA files it in the sweet flavor category.
What does Trehalose, dihydrate smell and taste like, and where is it used?
The odor of Trehalose, dihydrate is sweet, mild, subtle, neutral. On the palate it is sweet, pleasant, smooth. Typical uses are beverage, confection, baked goods and snacks.
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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as TREHALOSE, DIHYDRATE under CAS 6138-23-4 and carries its FEMA number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.