SP: Proposed Significant New Use Rule
Indicates a substance that is identified in a proposed Significant New Use Rule.
178 substances carry it in the July 2026 release, of which 170 are designated active.
What it obliges
No significant new use notice yet. Export notification under TSCA section 12(b) already applies, because 40 CFR 721.20 reaches substances named in a proposed rule as well as a final one.
What this flag does not establish
A proposed rule may change or may never be finalized. Read the proposal.
Substances carrying SP
Showing 100 of 178, active substances first. Search the full Inventory for a specific one.
| CAS number | Substance | Status | Other flags |
|---|---|---|---|
| 1017237-78-3 | 2-Propenoic acid, 2-[methyl[(1,1,2,2,3,3,4,4,4-nonafluorobutyl)sulfonyl]amino]ethyl ester, telomer with 3-mercapto-1,2-propanediol, 2-methyloxirane polymer with oxirane di-2-propenoate, and 2-methyloxirane polymer with oxirane mono-2-propenoate, tert-Bu 2-ethylhexaneperoxoate-initiated | Active | PMN 5E UVCB |
| 1078712-88-5 | Thiols, C4-20, .gamma.-.omega.-perfluoro, telomers with acrylamide and acrylic acid, sodium salts | Active | PMN S UVCB |
| 1078715-61-3 | 1-Propanaminium, 3-amino-N-(carboxymethyl)-N,N-dimethyl-, N-[2-[(.gamma.-.omega.-perfluoro-C4-20-alkyl)thio]acetyl] derivs., inner salts | Active | PMN S UVCB |
| 1227870-90-7 | Oxirane, 2-methyl-, polymer with 2,4-diisocyanato-1-methylbenzene, 2-methyloxirane polymer with oxirane ether with 1,2,3-propanetriol (3:1), and oxirane, cashew nutshell liq.- and Pr alc.-blocked | Active | PMN 5E UVCB |
| 2378512-59-3 | Fatty acids, soya, reaction products with ammonia-ethanolamine reaction by-products | Active | PMN 5E UVCB |
| 2450324-50-0 | Silsesquioxanes, Me vinyl, hydroxy- and methoxy- and [(trimethylsilyl)oxy]-terminated | Active | PMN 5E UVCB |
| 2576531-09-2 | Oils, sandalwood, santalene synthase-modified Rhodobacter sphaeroides-fermented, from D-glucose, oxidized | Active | PMN 5E UVCB |
| 2639393-45-4 | 2-Butanone, oxime, reaction products with trimethoxymethylsilane | Active | PMN 5E UVCB |
| 2728655-42-1 | Alcohols, C8-16, .gamma.-.omega.-perfluoro, reaction products with 1,6-diisocyanatohexane, glycidol and stearyl alc. | Active | PMN S UVCB |
| 2730864-66-9 | 1-Propanaminium, 3-amino-N-(carboxymethyl)-N,N-dimethyl-, N-[(.gamma.-.omega.-perfluoro-C6-14-alkyl)sulfonyl] derivs., inner salts | Active | PMN UVCB |
| 2796383-42-9 | Silsesquioxanes, 3-mercaptopropyl, polymers with silicic acid (H4SiO4) tetra-Et ester, [(trimethylsilyl)oxy]-terminated | Active | PMN 5E UVCB |
| 70969-47-0 | Thiols, C8-20, .gamma.-.omega.-perfluoro, telomers with acrylamide | Active | FRI S UVCB |
| 90552-04-8 | 2-Propenoic acid, 2-methyl-, C13-15-branched and linear alkyl esters | Active | PMN 5E UVCB |
| 1000399-21-2 | 4,8,11-Dodecatrienal | Active | PMN 5E |
| 1042950-30-0 | 1,2-Ethanediamine, N1,N2-dimethyl-N1-(1-methylethyl)-N2-[2-[methyl(1-methylethyl)amino]ethyl]- | Active | PMN 5E |
| 1159570-68-9 | Maltodextrin, octadecanoate | Active | PMN 5E |
| 1163-19-5 | Benzene, 1,1'-oxybis[2,3,4,5,6-pentabromo- | Active | R T |
| 125476-71-3 | Silicic acid (H4SiO4), sodium salt (1:2), reaction products with chlorotrimethylsilane and 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanol | Active | PMN UVCB |
| 1427037-93-1 | 2-Propenoic acid, 2-methyl-, polymer with 2-hydroxyethyl 2-methyl-2-propenoate phosphate and 2-propenoic acid, sodium salt, peroxydisulfuric acid ([(HO)S(O)2]2O2) sodium salt (1:2)- and sodium (disulfite) (2:1)-initiated | Active | PMN UVCB |
| 1514-82-5 | 1-Propene, 2-bromo-3,3,3-trifluoro- | Active | PMN 5E |
| 1516876-47-3 | Maltodextrin, decanoate | Active | PMN 5E |
| 1516876-50-8 | Maltodextrin, hexadecanoate | Active | PMN 5E |
| 1574548-27-8 | Cyclohexanamine, N,N-dimethyl-, compds. with 3-(cyclohexylamino)-1-propanesulfonic acid-blocked 5-isocyanato-1-(isocyanatomethyl)-1,3,3-trimethylcyclohexane homopolymer | Active | PMN UVCB |
| 1689576-35-9 | Hexane, 1,6-diisocyanato-, homopolymer, acrylic acid-polyethylene glycol ether with trimethylolpropane (3:1) reaction products-blocked | Active | PMN UVCB |
| 1800419-55-9 | Benzene, 1,1'-oxybis-, branched eicosyl derivs. | Active | PMN UVCB |
| 18611-43-3 | 1-Propene, 1,1,3,3-tetrachloro- | Active | PMN 5E |
| 1911605-95-2 | 1H-Pyrrole-2,5-dione, 1,1'-C36-alkylenebis- | Active | PMN UVCB |
| 2263959-83-5 | 1-Tetradecene, homopolymer, hydrogenated, by-products from, C28-42 fraction | Active | PMN UVCB |
| 2306219-11-2 | Fatty acids, C18-unsatd., dimers, hydrogenated, polymers with 1,6-hexanediol and 1,1'-methylenebis[4-isocyanatobenzene] | Active | PMN UVCB |
| 2413186-32-8 | Coal, brown, ammoxidized | Active | PMN UVCB |
| 2414071-06-8 | 1H-Pyrrole-2,5-dione, 3-methyl-, 1,1'-C36-alkylenebis- | Active | PMN UVCB |
| 2449089-78-3 | 1,4-Cyclohexanedicarboxylic acid, 1,4-dinonyl ester, branched and linear | Active | PMN UVCB |
| 2479-46-1 | Benzenamine, 4,4'-[1,3-phenylenebis(oxy)]bis- | Active | PMN 5E |
| 2489743-82-8 | Benzene, [2-[(2-methyl-1-undecen-1-yl)oxy]ethyl]- | Active | PMN 5E |
| 2568-33-4 | 1,3-Butanediol, 3-methyl- | Active | PMN S |
| 2736503-99-2 | Maltodextrin, octanoate | Active | PMN 5E |
| 2736504-00-8 | Maltodextrin, tetradecanoate | Active | PMN 5E |
| 332350-90-0 | Phosphonium, tributyl(2-methoxypropyl)-, salt with 1,1,2,2,3,3,4,4,4-nonafluoro-N-methyl-1-butanesulfonamide (1:1) | Active | PMN 5E |
| 332350-93-3 | Phosphonium, triphenyl(phenylmethyl)-, salt with 1,1,2,2,3,3,4,4,4-nonafluoro-N-methyl-1-butanesulfonamide (1:1) | Active | PMN 5E |
| 35203-06-6 | Benzenamine, 2-ethyl-6-methyl-N-methylene- | Active | PMN TP |
| 403616-34-2 | Siloxanes and Silicones, di-Me, 3-[3-carboxy-2(or 3)-(octenyl)-1-oxopropoxy]propyl group-terminated | Active | PMN UVCB |
| 460314-45-8 | 1-Butene, 3,3,4,4,4-pentafluoro-, polymer with ethene and 1,1,2,2-tetrafluoroethene | Active | PMN 5E |
| 512180-33-5 | Maltodextrin, dodecanoate | Active | PMN 5E |
| 595585-15-2 | D-Glucurono-D-gluco-6-deoxy-L-mannan, acetate, calcium magnesium potassium sodium salt | Active | PMN S |
| 61789-72-8 | Quaternary ammonium compounds, benzyl(hydrogenated tallow alkyl)dimethyl, chlorides | Active | TP UVCB |
| 61790-13-4 | Naphthenic acids, sodium salts | Active | TP UVCB |
| 64194-22-5 | 2-Propenoic acid, 1,1'-(3-methyl-1,5-pentanediyl) ester | Active | PMN S |
| 65996-91-0 | Distillates (coal tar), upper | Active | TP UVCB |
| 68187-47-3 | 1-Propanesulfonic acid, 2-methyl-, 2-[[1-oxo-3-[(.gamma.-.omega.-perfluoro-C4-16-alkyl)thio]propyl]amino] derivs., sodium salts | Active | S UVCB |
| 68308-01-0 | Tail gas (petroleum), cracked distillate hydrotreater stripper | Active | TP UVCB |
| 68391-08-2 | Alcohols, C8-14, .gamma.-.omega.-perfluoro | Active | S UVCB |
| 68478-20-6 | Residues (petroleum), steam-cracked petroleum distillates cyclopentadiene conc., C4-cyclopentadiene-free | Active | TP UVCB |
| 68526-82-9 | Alkenes, C6-10, hydroformylation products, high-boiling | Active | TP UVCB |
| 68909-77-3 | Ethanol, 2,2'-oxybis-, reaction products with ammonia, morpholine derivs. residues | Active | TP UVCB |
| 8007-45-2 | Tar, coal | Active | TP UVCB |
| 91052-16-3 | Glycerides, C16-18 and C18-unsatd. mono- and di-, citrates | Active | PMN UVCB |
| 91742-21-1 | Methanesulfonamide, 1,1,1-trifluoro-N-[(trifluoromethyl)sulfonyl]-, sodium salt (1:1) | Active | PMN 5E |
| 960253-23-0 | 2-Tridecenoic acid, 2-acetyl-4-methyl-, ethyl ester | Active | PMN 5E |
| 97489-04-8 | Fats and Glyceridic oils, vegetable, sulfonated, sodium salts | Active | PMN UVCB |
| 100-53-8 | Benzenemethanethiol | Active | TP |
| 100545-50-4 | 1-Decanamine, N-decyl-N-methyl-, N-oxide | Active | PMN |
| 103983-77-3 | 2,7-Nonadien-4-ol, 4,8-dimethyl- | Active | PMN |
| 104-91-6 | Phenol, 4-nitroso- | Active | TP |
| 110-03-2 | 2,5-Hexanediol, 2,5-dimethyl- | Active | TP |
| 112-98-1 | 5,8,11,14,17-Pentaoxaheneicosane | Active | PMN |
| 124-63-0 | Methanesulfonyl chloride | Active | TP |
| 1333341-34-6 | 4H-Pyran-4-one, 3-[(2,5-dihydro-4-methyl-5-oxo-2-furanyl)oxy]-2-methyl- | Active | PMN |
| 1338237-62-9 | Isocyanic acid, polymethylenepolyphenylene ester, polymer with 1,1'-methylenebis[isocyanatobenzene] and 2-methyloxirane polymer with oxirane ether with 1,2,3-propanetriol (3:1) | Active | PMN |
| 1370699-98-1 | Ethanone, 1-(5-propyl-1,3-benzodioxol-2-yl)- | Active | PMN |
| 1374760-95-8 | Acetamide, 2-(4-methylphenoxy)-N-1H-pyrazol-3-yl-N-(2-thienylmethyl)- | Active | PMN |
| 142-30-3 | 3-Hexyne-2,5-diol, 2,5-dimethyl- | Active | TP |
| 1558862-08-0 | Carbonic acid, dimethyl ester, polymer with 1,4-diisocyanatobenzene, 1,6-hexanediol and 1,5-pentanediol | Active | PMN |
| 1631145-48-6 | Cyclohexanol, 4-ethylidene-2-propoxy- | Active | PMN |
| 1631145-49-7 | Cyclohexanol, 5-ethylidene-2-propoxy- | Active | PMN |
| 17741-60-5 | 2-Propenoic acid, 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,12-heneicosafluorododecyl ester | Active | S |
| 1821051-37-9 | Propanoic acid, 2,2-dimethyl-, 1-methyl-2-(1-methylethoxy)-2-oxoethyl ester | Active | PMN |
| 1836131-73-7 | Formic acid, compd. with 2-methyl-1,5-pentanediamine (2:1) | Active | PMN |
| 2043-53-0 | Decane, 1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8-heptadecafluoro-10-iodo- | Active | S |
| 2043-54-1 | Dodecane, 1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10-heneicosafluoro-12-iodo- | Active | S |
| 2098904-74-4 | 2-Propanol, 1-amino-, compd. with .alpha.-sulfo-.omega.-(octyloxy)poly(oxy-1,2-ethanediyl) (1:1) | Active | PMN |
| 2098904-80-2 | 2-Propanol, 1-amino-, compd. with .alpha.-sulfo-.omega.-(decyloxy)poly(oxy-1,2-ethanediyl) (1:1) | Active | PMN |
| 2222732-45-6 | Propanedioic acid, 2,2-bis(hydroxymethyl)-, 1,3-dihexyl ester | Active | PMN |
| 2307636-51-5 | 2,4-Hexadienoic acid, 1,1'-[2-ethyl-2-[[(1-oxo-2,4-hexadien-1-yl)oxy]methyl]-1,3-propanediyl] ester | Active | PMN |
| 2364431-09-2 | Propanedioic acid, 2-methylene-, 1,3-diethyl ester, polymer with 1,4-butanediol | Active | PMN |
| 24991-53-5 | Poly(oxy-1,2-ethanediyl), .alpha.-(2-aminoethyl)-.omega.-(2-aminoethoxy)- | Active | PMN |
| 24991-55-7 | Poly(oxy-1,2-ethanediyl), .alpha.-methyl-.omega.-methoxy- | Active | FRI |
| 25608-40-6 | L-Aspartic acid, homopolymer | Active | PMN |
| 26027-38-3 | Poly(oxy-1,2-ethanediyl), .alpha.-(4-nonylphenyl)-.omega.-hydroxy- | Active | FRI |
| 26172-55-4 | 3(2H)-Isothiazolone, 5-chloro-2-methyl- | Active | PMN |
| 2682-20-4 | 3(2H)-Isothiazolone, 2-methyl- | Active | PMN |
| 27905-45-9 | 2-Propenoic acid, 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl ester | Active | S |
| 28106-30-1 | Benzene, ethenylethyl- | Active | TP |
| 30046-31-2 | Tetradecane, 1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12-pentacosafluoro-14-iodo- | Active | S |
| 304855-14-9 | Carbamic acid, N-(3-isocyanatomethylphenyl)-, 2-[2-(2-butoxyethoxy)ethoxy]ethyl ester | Active | PMN |
| 31885-97-9 | Poly(oxy-1,2-ethanediyl), .alpha.-butyl-.omega.-butoxy- | Active | PMN |
| 335-66-0 | Octanoyl fluoride, 2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-pentadecafluoro- | Active | S |
| 335-67-1 | Octanoic acid, 2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-pentadecafluoro- | Active | S |
| 335-95-5 | Octanoic acid, 2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-pentadecafluoro-, sodium salt (1:1) | Active | S |
| 35203-08-8 | Benzenamine, 2,6-diethyl-N-methylene- | Active | TP |
| 37205-87-1 | Poly(oxy-1,2-ethanediyl), .alpha.-(isononylphenyl)-.omega.-hydroxy- | Active | FRI |
From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish, so a substance absent from this data is not thereby unflagged.