Flavor ingredient regulatory record
1,1-Dipropoxyethane
1,1-Dipropoxyethane is an ether in the fruity family, FEMA GRAS under FEMA number 4688 (CAS 105-82-8). Its odor is sweet, fruity, floral, estery, light.
- FEMA
- 4688
- CAS
- 105-82-8
- EU FL
- 06.034
- Formula
- C8H18O2
- EC
- 203-335-2
GRAS status: FEMA GRAS, publication 25. Recorded by FDA in the Substances Added to Food inventory under CAS 105-82-8.
Structure
Identity
Also known as: Propane, 1,1′-[ethylidenebis(oxy)]bis-, Acetaldehyde, dipropyl acetal, 1,1′-[Ethylidenebis(oxy)]bis[propane], Ethane, 1,1-dipropoxy-, 1-(1-Propoxyethoxy)propane, acetaldehyde dipropyl acetal, dipropyl acetal, n-propyl acetal, propane, 1,1'-[ethylidenebis(oxy)]bis-, acetaldehyde, dipropyl acetal, acetaldehyde-di-n-propyl acetal, 1,1'-(ethylidenebis(oxy))bispropane.
Can 1,1-Dipropoxyethane be labeled natural?
Nature occurrence: Not yet found in nature (provisional).
Nature occurrence has not been settled for this substance, so the natural or artificial class is not stated here. The FEMA GRAS status does not depend on it.
Regulatory status, with citations
United States
1,1-Dipropoxyethane is FEMA GRAS under FEMA number 4688. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
Listed on the Union List of flavouring substances as FL 06.034, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (SCF/CoE). The UK retains the same list.
JECFA (WHO / FAO)
1,1-Dipropoxyethane has not been evaluated by JECFA as a flavouring agent, or no evaluation is on file.
Other US flags
Not on the California Proposition 65 list.
TSCA Inventory status
A flavor ingredient is also an industrial chemical. 1,1-Dipropoxyethane appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 105-82-8, where EPA names it Propane, 1,1'-[ethylidenebis(oxy)]bis-.
Active in US commerce
EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.
EPA publishes no regulatory flags on this listing. What the flags mean.
From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.
Odor and taste
Odor: Sweet, fruity, floral, estery, light.
Where it is used
1,1-Dipropoxyethane is used in beverage, confection, flavoring agents and fruity desserts, typically as a fruity note.
Structurally similar flavor ingredients
Flavor ingredients with a GRAS determination closest to 1,1-Dipropoxyethane by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.
| Material | FEMA | Similarity | Occurrence |
|---|---|---|---|
| 1-Isobutoxy-1-ethoxyethane | 4528 | 89% | Not determined |
| Tripropylamine | 4247 | 78% | Not determined |
| 2,5-Diethyltetrahydrofuran | 3743 | 75% | In nature |
| 4-Heptanone | 2546 | 65% | In nature |
| 6-Undecanone | 4022 | 64% | In nature |
More ethers in this index
Benzyl butyl ether · 2,4-Dimethyl-1,3-dioxolane · (2,2-Diethoxyethyl)benzene · Butyl beta-naphthyl ether · Digeranyl ether · sec-Butyl ethyl ether
1,1-Dipropoxyethane FAQ
Is 1,1-Dipropoxyethane on the FEMA GRAS list?
It is. FEMA number 4688 covers 1,1-Dipropoxyethane. It is also codified at 21 CFR 172.515.
What is the FEMA number for 1,1-Dipropoxyethane?
The FEMA number for 1,1-Dipropoxyethane is 4688 and its CAS registry number is 105-82-8. FEMA files it in the fruity flavor category.
Is 1,1-Dipropoxyethane approved in the EU?
1,1-Dipropoxyethane is on the EU Union List of flavouring substances as FL 06.034 (Annex I Part A) under Regulation 1334/2008.
What is 1,1-Dipropoxyethane used for?
1,1-Dipropoxyethane is described as sweet, fruity, floral, estery, light. It shows up in beverage, confection, flavoring agents and fruity desserts.
Ingredient lookup
Check an ingredient
Start typing to search the ingredient corpus.
Or browse every ingredient page, A to Z.
Guides: What Is FEMA GRAS? · Natural vs artificial · Filing a GRAS notification
Check 1,1-Dipropoxyethane in a formula
Screened against FEMA GRAS, 21 CFR and EU rules as you build. Free to start.
Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as 1,1-DIPROPOXYETHANE under CAS 105-82-8 and carries its FEMA number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.