Flavor ingredient regulatory record

1-Isobutoxy-1-ethoxyethane

1-Isobutoxy-1-ethoxyethane is an ester in the fruity family, FEMA GRAS under FEMA number 4528 (CAS 6986-51-2). Its odor is sweet, fruity, floral, estery, slightly woody.

FEMA
4528
CAS
6986-51-2
JECFA
2305
EU FL
06.091
Formula
C8H18O2
EC
230-251-3

GRAS status: FEMA GRAS, publication 24. Recorded by FDA in the Substances Added to Food inventory under CAS 6986-51-2.

Structure

2D structure of 1-Isobutoxy-1-ethoxyethane
Structure of 1-Isobutoxy-1-ethoxyethane, C8H18O2. Drawn from the canonical SMILES.

Identity

IUPAC name 1-(1-ethoxyethoxy)-2-methylpropane
CAS number 6986-51-2
FEMA number 4528
Molecular formula C8H18O2
Molecular weight 146.23 g/mol
SMILES CCOC(C)OCC(C)C
InChIKey YEKSEJHZJGHKBN-UHFFFAOYSA-N
PubChem CID 110941
EC number 230-251-3
FDA UNII AGI3541J26
EPA DTXSID DTXSID90863969
Chemical class Ester
Boiling point 155 °C
Flash point 62 °C

Also known as: Propane, 1-(1-ethoxyethoxy)-2-methyl-, Acetaldehyde, ethyl isobutyl acetal, Ethane, 1-ethoxy-1-isobutoxy-, 1-(1-Ethoxyethoxy)-2-methylpropane, 1-Ethoxy-1-(2-methylpropoxy)ethane, 1-Ethoxy-1-isobutoxyethane, 1-(1-ethoxyethoxy)-2-methylpropane, acetaldehyde ethyl isobutyl acetal, 1-ethoxy-1-(2-methylpropoxy)ethane, acetaldehyde, ethyl 2-methylpropyl acetal, propane, 1-(1-ethoxyethoxy)-2-methyl-, 1-ethoxy-1-isobutoxyethane.

Can 1-Isobutoxy-1-ethoxyethane be labeled natural?

Nature occurrence: Not yet found in nature (provisional).

Nature occurrence has not been settled for this substance, so the natural or artificial class is not stated here. The FEMA GRAS status does not depend on it.

Regulatory status, with citations

United States

1-Isobutoxy-1-ethoxyethane is FEMA GRAS under FEMA number 4528. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 06.091, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.

JECFA (WHO / FAO)

JECFA number 2305.

Other US flags

Not on the California Proposition 65 list.

Odor and taste

Odor: Sweet, fruity, floral, estery, slightly woody.

Where it is used

1-Isobutoxy-1-ethoxyethane is used in beverage, confection, fruit flavors and baked goods, typically as a fruity note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to 1-Isobutoxy-1-ethoxyethane by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
1,1-Dipropoxyethane468889%Not determined
Crotonic acid390868%In nature
Butyl isobutyrate218865%In nature

More esters in this index

Isoamyl formate · Benzyl acetoacetate · 6-[5(6)-Decenoyloxy]decanoic acid · Allyl cyclohexane butyrate · Propyl heptanoate · Ethyl 3-(methylthio)-trans-2-propenoate

1-Isobutoxy-1-ethoxyethane FAQ

Does 1-Isobutoxy-1-ethoxyethane have FEMA GRAS status?

1-Isobutoxy-1-ethoxyethane holds FEMA GRAS status under FEMA number 4528. It is also codified at 21 CFR 172.515.

How do I cite 1-Isobutoxy-1-ethoxyethane by FEMA or CAS number?

Cite 1-Isobutoxy-1-ethoxyethane as FEMA 4528 or CAS 6986-51-2; both point to the same entry. FEMA files it in the fruity flavor category.

Can 1-Isobutoxy-1-ethoxyethane be used in the EU and UK?

1-Isobutoxy-1-ethoxyethane is on the EU Union List of flavouring substances as FL 06.091 (Annex I Part A) under Regulation 1334/2008.

Has JECFA evaluated 1-Isobutoxy-1-ethoxyethane?

Yes. JECFA number 2305.

What does 1-Isobutoxy-1-ethoxyethane smell and taste like, and where is it used?

The odor of 1-Isobutoxy-1-ethoxyethane is sweet, fruity, floral, estery, slightly woody. Typical uses are beverage, confection, fruit flavors and baked goods.

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as ACETALDEHYDE ETHYL ISOBUTYL ACETAL under CAS 6986-51-2 and carries its FEMA number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.