Flavor ingredient regulatory record

1-Methyl-1H-pyrrole-2-carboxaldehyde

1-Methyl-1H-pyrrole-2-carboxaldehyde is an aldehyde in the fruity family, FEMA GRAS under FEMA number 4332 (CAS 1192-58-1). Its odor is sweet, nutty, roasted, earthy, floral.

FEMA
4332
CAS
1192-58-1
JECFA
2152
Formula
C6H7NO
EC
214-755-0

GRAS status: FEMA GRAS, publication 23. Recorded by FDA in the Substances Added to Food inventory under CAS 1192-58-1.

Structure

2D structure of 1-Methyl-1H-pyrrole-2-carboxaldehyde
Structure of 1-Methyl-1H-pyrrole-2-carboxaldehyde, C6H7NO. Drawn from the canonical SMILES.

Identity

IUPAC name 1-methylpyrrole-2-carbaldehyde
CAS number 1192-58-1
FEMA number 4332
Molecular formula C6H7NO
Molecular weight 109.13 g/mol
SMILES Cn1cccc1C=O
InChIKey OUKQTRFCDKSEPL-UHFFFAOYSA-N
PubChem CID 14504
EC number 214-755-0
FDA UNII M0HYH3D7SX
EPA DTXSID DTXSID20152338
Chemical class Aldehyde
Boiling point 73 °C
Flash point 19 °C

Also known as: 1H-Pyrrole-2-carboxaldehyde, 1-methyl-, Pyrrole-2-carboxaldehyde, 1-methyl-, 1-Methyl-2-formylpyrrole, N-Methyl-2-formylpyrrole, N-Methylpyrrole-2-carboxaldehyde, 2-Formyl-1-methylpyrrole, 1-Methylpyrrole-2-carboxaldehyde, N-Methyl-2-pyrrolylcarboxaldehyde, N-Methyl-2-pyrrolaldehyde, N-Methylpyrrole-2-carbaldehyde, 2-Formyl-N-methylpyrrole, NSC 72386.

Can 1-Methyl-1H-pyrrole-2-carboxaldehyde be labeled natural?

1-Methyl-1H-pyrrole-2-carboxaldehyde occurs in nature, so the label depends on the route: 1-Methyl-1H-pyrrole-2-carboxaldehyde won from a natural source by a physical, enzymatic or microbiological process is natural flavor in the United States, and synthesized 1-Methyl-1H-pyrrole-2-carboxaldehyde is artificial. The EU and UK grant the natural claim only to that natural route; Mercosur and Mexico call synthetic material identical-to-natural.

United States
Natural or artificial, by process
European Union and UK
Natural only from natural material
Mercosur and Mexico
Natural or identical-to-natural

How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.

Regulatory status, with citations

United States

1-Methyl-1H-pyrrole-2-carboxaldehyde is FEMA GRAS under FEMA number 4332. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

1-Methyl-1H-pyrrole-2-carboxaldehyde was on the Union List of flavouring substances as FL 14.163 when Regulation (EU) 872/2012 adopted the list, and the entry has since been withdrawn. It does not appear in the current consolidated text of Regulation (EC) 1334/2008. Check the amending regulations for the conditions that applied to existing stock, and treat EU or UK use as closed unless another route covers it.

JECFA (WHO / FAO)

JECFA number 2152, evaluated at the 76th meeting in 2012. no safety concern at current levels of intake.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

Odor and taste

Odor: Sweet, nutty, roasted, earthy, floral.

Where it is used

1-Methyl-1H-pyrrole-2-carboxaldehyde is used in beverage, confection, bakery, flavoring and snacks, typically as a fruity note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to 1-Methyl-1H-pyrrole-2-carboxaldehyde by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
Furfural248983%In nature
1-Ethyl-2-pyrrolecarboxaldehyde431782%In nature
5-Methyl-3(2H)-furanone417677%In nature
1-Methyl-2-acetylpyrrole318476%In nature
1-Ethyl-2-acetylpyrrole314773%In nature

More aldehydes in this index

3-Methylhexanal · Octadec-9-enal · trans-2-Hexenal glyceryl acetal · 4-Decenal · Nonanal · p-Isopropylphenylacetaldehyde

1-Methyl-1H-pyrrole-2-carboxaldehyde FAQ

Is 1-Methyl-1H-pyrrole-2-carboxaldehyde FEMA GRAS?

Yes. The FEMA Expert Panel lists 1-Methyl-1H-pyrrole-2-carboxaldehyde as GRAS under FEMA number 4332. It is also codified at 21 CFR 172.515.

What are the FEMA and CAS numbers for 1-Methyl-1H-pyrrole-2-carboxaldehyde?

1-Methyl-1H-pyrrole-2-carboxaldehyde is FEMA 4332, CAS 1192-58-1. FEMA files it in the fruity flavor category.

Does 1-Methyl-1H-pyrrole-2-carboxaldehyde count as natural in the US and the EU?

Since 1-Methyl-1H-pyrrole-2-carboxaldehyde is found in nature, US labeling follows how it was obtained: natural flavor from a natural source and a natural process, artificial when 1-Methyl-1H-pyrrole-2-carboxaldehyde is synthesized. The EU and UK grant the natural claim only to that natural route; Mercosur and Mexico call synthetic material identical-to-natural.

Is 1-Methyl-1H-pyrrole-2-carboxaldehyde approved in the EU?

No EU FL number is on file for 1-Methyl-1H-pyrrole-2-carboxaldehyde. It has a JECFA evaluation (JECFA 2152), which the EU list draws on, but the Union List entry itself should be confirmed before EU use.

Has JECFA evaluated 1-Methyl-1H-pyrrole-2-carboxaldehyde?

Yes. JECFA number 2152, evaluated at the 76th meeting in 2012. Conclusion: no safety concern at current levels of intake.

How is 1-Methyl-1H-pyrrole-2-carboxaldehyde described, and where does it show up?

Flavorists describe 1-Methyl-1H-pyrrole-2-carboxaldehyde as sweet, nutty, roasted, earthy, floral. It is used in beverage, confection, bakery, flavoring and snacks.

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Guides: What Is FEMA GRAS? · Natural vs artificial · Filing a GRAS notification

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as 1-METHYL-1H-PYRROLE-2-CARBOXALDEHYDE under CAS 1192-58-1 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.