Flavor ingredient regulatory record
2,4-Dimethyl-1,3-dioxolane
2,4-Dimethyl-1,3-dioxolane is an ether in the fruity family, FEMA GRAS under FEMA number 4099 (CAS 3390-12-3). Its odor is sweet, fruity, floral, estery, fresh.
- FEMA
- 4099
- CAS
- 3390-12-3
- JECFA
- 1711
- EU FL
- 06.077
- Formula
- C5H10O2
- EC
- 222-221-3
GRAS status: FEMA GRAS, publication 22. Recorded by FDA in the Substances Added to Food inventory under CAS 3390-12-3.
Structure
Identity
Also known as: 1,3-Dioxolane, 2,4-dimethyl-, Acetaldehyde cyclic propylene acetal, Propylene acetal, 1,3-dioxolane, 2,4-dimethyl-, propylene acetal, acetaldehyde cyclic propylene acetal, 2,4-dimethyl-1,3-dioxolane [fhfi], 1,3-dioxolane, 2,4-dimethyl-, (2r-cis)-, 2,4-dimethyl, 1,3-dioxalone, acetaldehydepropylenegylcolacetal, 1,3-dioxolane, 2,4-dimethyl, cis, 24-dimethyl-13-dioxolane.
Can 2,4-Dimethyl-1,3-dioxolane be labeled natural?
Nature occurrence: Not yet found in nature (provisional).
Nature occurrence has not been settled for this substance, so the natural or artificial class is not stated here. The FEMA GRAS status does not depend on it.
Regulatory status, with citations
United States
2,4-Dimethyl-1,3-dioxolane is FEMA GRAS under FEMA number 4099. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
Listed on the Union List of flavouring substances as FL 06.077, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.
JECFA (WHO / FAO)
JECFA number 1711, evaluated at the 68th meeting in 2007. no safety concern at current levels of intake.
Other US flags
Not on the California Proposition 65 list.
Odor and taste
Odor: Sweet, fruity, floral, estery, fresh.
Where it is used
2,4-Dimethyl-1,3-dioxolane is used in beverage, confection, fruit flavors, bakery and desserts, typically as a fruity note.
Structurally similar flavor ingredients
Flavor ingredients with a GRAS determination closest to 2,4-Dimethyl-1,3-dioxolane by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.
| Material | FEMA | Similarity | Occurrence |
|---|---|---|---|
| 2,4-Dimethyl-3-oxazoline | 4429 | 92% | In nature |
| gamma-Valerolactone | 3103 | 81% | In nature |
| 2,5-Dimethylfuran-3(2H)-one | 4101 | 80% | Not determined |
| 2,4,5-Trimethyl-delta-3-oxazoline | 3525 | 79% | In nature |
| Ethyl Acetate | 2414 | 75% | In nature |
More ethers in this index
1,1-Dipropoxyethane · beta-Naphthyl methyl ether · Isoeugenyl ethyl ether · Benzyl ethyl ether · Hydroquinone monoethyl ether · Benzyl butyl ether
2,4-Dimethyl-1,3-dioxolane FAQ
Does 2,4-Dimethyl-1,3-dioxolane have FEMA GRAS status?
2,4-Dimethyl-1,3-dioxolane holds FEMA GRAS status under FEMA number 4099. The Code of Federal Regulations lists it at 21 CFR 172.515.
How do I cite 2,4-Dimethyl-1,3-dioxolane by FEMA or CAS number?
Cite 2,4-Dimethyl-1,3-dioxolane as FEMA 4099 or CAS 3390-12-3; both point to the same entry. Its flavor category is fruity.
What does 2,4-Dimethyl-1,3-dioxolane smell and taste like, and where is it used?
The odor of 2,4-Dimethyl-1,3-dioxolane is sweet, fruity, floral, estery, fresh. Typical uses are beverage, confection, fruit flavors, bakery and desserts.
What did JECFA conclude about 2,4-Dimethyl-1,3-dioxolane?
JECFA evaluated 2,4-Dimethyl-1,3-dioxolane at the 68th meeting in 2007 under JECFA number 1711. The panel concluded: no safety concern at current levels of intake.
Can 2,4-Dimethyl-1,3-dioxolane be used in the EU and UK?
Yes. FL 06.077 is the Union List entry for 2,4-Dimethyl-1,3-dioxolane, annex I Part A, under Regulation 1334/2008, and the UK keeps the same list.
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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as 2,4-DIMETHYL-1,3-DIOXOLANE under CAS 3390-12-3 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.