Flavor ingredient regulatory record

2-Furyl methyl ketone

2-Furyl methyl ketone is a ketone in the fruity family, FEMA GRAS under FEMA number 3163 (CAS 1192-62-7). Its odor is sweet, caramel, nutty, roasted, buttery.

FEMA
3163
CAS
1192-62-7
JECFA
1503
EU FL
13.054
Formula
C6H6O2
EC
214-757-1

GRAS status: FEMA GRAS, publication 4. Recorded by FDA in the Substances Added to Food inventory under CAS 1192-62-7.

Structure

2D structure of 2-Furyl methyl ketone
Structure of 2-Furyl methyl ketone, C6H6O2. Drawn from the canonical SMILES.

Identity

IUPAC name 1-(furan-2-yl)ethanone
CAS number 1192-62-7
FEMA number 3163
Molecular formula C6H6O2
Molecular weight 110.11 g/mol
SMILES CC(=O)c1ccco1
InChIKey IEMMBWWQXVXBEU-UHFFFAOYSA-N
PubChem CID 14505
EC number 214-757-1
FDA UNII Q5ZRP80K02
EPA DTXSID DTXSID0051601
Chemical class Ketone
Boiling point 173 °C
Flash point 71 °C

Also known as: Ethanone, 1-(2-furanyl)-, Ketone, 2-furyl methyl, 1-(2-Furanyl)ethanone, Methyl 2-furyl ketone, 2-Furylethanone, 2-Acetylfuran, 1-(2-Furyl)ethanone, α-Acetylfuran, NSC 4665, NSC 49133, 1-(Furan-2-yl)ethan-1-one, 2-acetylfuran.

Can 2-Furyl methyl ketone be labeled natural?

The process decides for 2-Furyl methyl ketone. It occurs in nature, so a natural-source, natural-process material is natural flavor in the US and synthetic 2-Furyl methyl ketone is artificial. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.

United States
Natural or artificial, by process
European Union and UK
Natural only from natural material
Mercosur and Mexico
Natural or identical-to-natural

How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.

Regulatory status, with citations

United States

2-Furyl methyl ketone is FEMA GRAS under FEMA number 3163. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 13.054, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.

JECFA (WHO / FAO)

JECFA number 1503, evaluated at the 86th meeting in 2018. No safety concern at current levels of intake when used as a flavouring agent.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

TSCA Inventory status

A flavor ingredient is also an industrial chemical. 2-Furyl methyl ketone appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 1192-62-7, where EPA names it Ethanone, 1-(2-furanyl)-.

Active in US commerce

EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.

EPA publishes no regulatory flags on this listing. What the flags mean.

From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.

Odor and taste

Odor: Sweet, caramel, nutty, roasted, buttery. Detectable at about 10 ppm.

Where it is used

2-Furyl methyl ketone is used in beverage, confection, bakery and dairy, typically as a fruity note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to 2-Furyl methyl ketone by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
2-Ethylfuran367392%In nature
Furfuryl alcohol249183%In nature
2-Acetylthiazole332880%In nature
2-Methyl-3-(methylthio)furan394977%In nature
Furfuryl mercaptan249375%In nature

More ketones in this index

4-Hydroxyacetophenone · (+/-) [R-(E)]-5-Isopropyl-8-methylnona-6,8-dien-2-one · 9-Decen-2-one · 2-Butanone · Methyl beta-naphthyl ketone · 2,3-Hexanedione

2-Furyl methyl ketone FAQ

Does 2-Furyl methyl ketone have FEMA GRAS status?

2-Furyl methyl ketone holds FEMA GRAS status under FEMA number 3163. The Code of Federal Regulations lists it at 21 CFR 172.515.

How do I cite 2-Furyl methyl ketone by FEMA or CAS number?

Cite 2-Furyl methyl ketone as FEMA 3163 or CAS 1192-62-7; both point to the same entry. Its flavor category is fruity.

What does 2-Furyl methyl ketone smell and taste like, and where is it used?

The odor of 2-Furyl methyl ketone is sweet, caramel, nutty, roasted, buttery. Its odor threshold is about 10 ppm. Typical uses are beverage, confection, bakery and dairy.

What did JECFA conclude about 2-Furyl methyl ketone?

JECFA evaluated 2-Furyl methyl ketone at the 86th meeting in 2018 under JECFA number 1503. The panel concluded: No safety concern at current levels of intake when used as a flavouring agent.

Can 2-Furyl methyl ketone be used in the EU and UK?

Yes. FL 13.054 is the Union List entry for 2-Furyl methyl ketone, annex I Part A, under Regulation 1334/2008, and the UK keeps the same list.

Can 2-Furyl methyl ketone be labeled a natural flavor?

Nature makes 2-Furyl methyl ketone, which is why the US label turns on process. A natural route gives natural flavor; synthesis gives artificial 2-Furyl methyl ketone, same molecule. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic 2-Furyl methyl ketone identical-to-natural.

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as 2-FURYL METHYL KETONE under CAS 1192-62-7 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.