Flavor ingredient regulatory record
2-Methoxy-6-(2-propenyl)phenol
2-Methoxy-6-(2-propenyl)phenol is a phenol in the floral family, FEMA GRAS under FEMA number 4490 (CAS 579-60-2). Its odor is sweet, floral, spicy, herbal.
- FEMA
- 4490
- CAS
- 579-60-2
- JECFA
- 1528
- EU FL
- 04.096
- Formula
- C10H12O2
- EC
- 209-444-1
GRAS status: FEMA GRAS, publication 24. Recorded by FDA in the Substances Added to Food inventory under CAS 579-60-2.
Structure
Identity
Also known as: Phenol, 2-methoxy-6-(2-propen-1-yl)-, Phenol, 2-allyl-6-methoxy-, Phenol, 2-methoxy-6-(2-propenyl)-, Guaiacol, 6-allyl-, 2-Methoxy-6-(2-propen-1-yl)phenol, o-Eugenol, 6-Allyl-2-methoxyphenol, o-Allylguaiacol, 2-Allyl-6-methoxyphenol, 2-Hydroxy-3-methoxy-1-allylbenzene, NSC 406351, 2-Methoxy-6-prop-2-enylphenol.
Can 2-Methoxy-6-(2-propenyl)phenol be labeled natural?
Since 2-Methoxy-6-(2-propenyl)phenol is found in nature, US labeling follows how it was obtained: natural flavor from a natural source and a natural process, artificial when 2-Methoxy-6-(2-propenyl)phenol is synthesized. The EU and UK grant the natural claim only to that natural route; Mercosur and Mexico call synthetic material identical-to-natural.
- United States
- Natural or artificial, by process
- European Union and UK
- Natural only from natural material
- Mercosur and Mexico
- Natural or identical-to-natural
How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.
Regulatory status, with citations
United States
2-Methoxy-6-(2-propenyl)phenol is FEMA GRAS under FEMA number 4490. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
Listed on the Union List of flavouring substances as FL 04.096, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.
JECFA (WHO / FAO)
JECFA number 1528, evaluated at the 65th meeting in 2005. No safety concern at current levels of intake when used as a flavouring agent.
Other US flags
Not on the California Proposition 65 list.
Odor and taste
Odor: Sweet, floral, spicy, herbal.
Taste: Bitter, spicy, herbal.
Where it is used
2-Methoxy-6-(2-propenyl)phenol is used in beverage, confection, flavoring and cosmetics, typically as a floral note.
Structurally similar flavor ingredients
Flavor ingredients with a GRAS determination closest to 2-Methoxy-6-(2-propenyl)phenol by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.
| Material | FEMA | Similarity | Occurrence |
|---|---|---|---|
| 2-Methoxy-4-vinylphenol | 2675 | 80% | In nature |
| 4-Allyl-2,6-dimethoxyphenol | 3655 | 77% | In nature |
| Eugenol | 2467 | 73% | In nature |
| 4-Ethylguaiacol | 2436 | 67% | In nature |
| Methyl salicylate | 2745 | 66% | In nature |
More phenols in this index
4-Propenylphenol · m-Dimethoxybenzene · 2-Phenoxyethanol · Acetanisole · 2-Methoxy-4-vinylphenol · 1,2-Dimethoxybenzene
2-Methoxy-6-(2-propenyl)phenol FAQ
Is 2-Methoxy-6-(2-propenyl)phenol on the FEMA GRAS list?
It is. FEMA number 4490 covers 2-Methoxy-6-(2-propenyl)phenol. It is also codified at 21 CFR 172.515.
What is the FEMA number for 2-Methoxy-6-(2-propenyl)phenol?
The FEMA number for 2-Methoxy-6-(2-propenyl)phenol is 4490 and its CAS registry number is 579-60-2. FEMA files it in the floral flavor category.
Is 2-Methoxy-6-(2-propenyl)phenol natural or artificial?
2-Methoxy-6-(2-propenyl)phenol occurs in nature, so the label depends on the route: 2-Methoxy-6-(2-propenyl)phenol won from a natural source by a physical, enzymatic or microbiological process is natural flavor in the United States, and synthesized 2-Methoxy-6-(2-propenyl)phenol is artificial. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.
Is 2-Methoxy-6-(2-propenyl)phenol approved in the EU?
2-Methoxy-6-(2-propenyl)phenol is on the EU Union List of flavouring substances as FL 04.096 (Annex I Part A) under Regulation 1334/2008.
Has JECFA evaluated 2-Methoxy-6-(2-propenyl)phenol?
Yes. JECFA number 1528, evaluated at the 65th meeting in 2005. Conclusion: No safety concern at current levels of intake when used as a flavouring agent.
What is 2-Methoxy-6-(2-propenyl)phenol used for?
2-Methoxy-6-(2-propenyl)phenol is described as sweet, floral, spicy, herbal. On the palate it is bitter, spicy, herbal. It shows up in beverage, confection, flavoring and cosmetics.
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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as 2-METHOXY-6-(2-PROPENYL)PHENOL under CAS 579-60-2 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.