Flavor ingredient regulatory record

4-Allylphenol

4-Allylphenol is a phenol in the floral family, FEMA GRAS under FEMA number 4075 (CAS 501-92-8). Its odor is sweet, floral, spicy, herbal.

FEMA
4075
CAS
501-92-8
JECFA
1527
EU FL
04.058
Formula
C9H10O
EC
207-929-2

GRAS status: FEMA GRAS, publication 22. Recorded by FDA in the Substances Added to Food inventory under CAS 501-92-8.

Structure

2D structure of 4-Allylphenol
Structure of 4-Allylphenol, C9H10O. Drawn from the canonical SMILES.

Identity

IUPAC name 4-prop-2-enylphenol
CAS number 501-92-8
FEMA number 4075
Molecular formula C9H10O
Molecular weight 134.18 g/mol
SMILES C=CCc1ccc(O)cc1
InChIKey RGIBXDHONMXTLI-UHFFFAOYSA-N
PubChem CID 68148
EC number 207-929-2
FDA UNII Q5ER4K6969
EPA DTXSID DTXSID60198210
Chemical class Phenol
Boiling point 110 °C
Flash point 39 °C

Also known as: Phenol, 4-(2-propen-1-yl)-, Phenol, p-allyl-, Chavicol, Phenol, 4-(2-propenyl)-, 4-(2-Propen-1-yl)phenol, p-Allylphenol, γ-(p-Hydroxyphenyl)-α-propylene, p-Hydroxyallylbenzene, 3-(p-Hydroxyphenyl)-1-propene, NSC 290195, 4-(2-Propenyl)phenol, (4-Hydroxyphenyl)-2-propene.

Can 4-Allylphenol be labeled natural?

The process decides for 4-Allylphenol. It occurs in nature, so a natural-source, natural-process material is natural flavor in the US and synthetic 4-Allylphenol is artificial. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.

United States
Natural or artificial, by process
European Union and UK
Natural only from natural material
Mercosur and Mexico
Natural or identical-to-natural

How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.

Regulatory status, with citations

United States

4-Allylphenol is FEMA GRAS under FEMA number 4075. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 04.058, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.

JECFA (WHO / FAO)

JECFA number 1527, evaluated at the 65th meeting in 2005. no safety concern at current levels of intake.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

Odor and taste

Odor: Sweet, floral, spicy, herbal.

Taste: Bitter, spicy, aromatic.

Where it is used

4-Allylphenol is used in beverage, confection, flavoring and savory dishes, typically as a floral note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to 4-Allylphenol by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
p-Propylphenol364987%In nature
4-Propenylphenol406287%In nature
2-(4-Hydroxyphenyl)ethylamine421579%In nature
Eugenol246774%In nature
3-Phenylpropionaldehyde288770%In nature

More phenols in this index

Indole · 2-Methoxy-4-vinylphenol · Isoeugenol · p-Dimethoxybenzene · m-Dimethoxybenzene · Acetanisole

4-Allylphenol FAQ

Does 4-Allylphenol have FEMA GRAS status?

4-Allylphenol holds FEMA GRAS status under FEMA number 4075. The Code of Federal Regulations lists it at 21 CFR 172.515.

How do I cite 4-Allylphenol by FEMA or CAS number?

Cite 4-Allylphenol as FEMA 4075 or CAS 501-92-8; both point to the same entry. Its flavor category is floral.

What does 4-Allylphenol smell and taste like, and where is it used?

The odor of 4-Allylphenol is sweet, floral, spicy, herbal. On the palate it is bitter, spicy, aromatic. Typical uses are beverage, confection, flavoring and savory dishes.

What did JECFA conclude about 4-Allylphenol?

JECFA evaluated 4-Allylphenol at the 65th meeting in 2005 under JECFA number 1527. The panel concluded: no safety concern at current levels of intake.

Can 4-Allylphenol be used in the EU and UK?

Yes. FL 04.058 is the Union List entry for 4-Allylphenol, annex I Part A, under Regulation 1334/2008, and the UK keeps the same list.

Can 4-Allylphenol be labeled a natural flavor?

Nature makes 4-Allylphenol, which is why the US label turns on process. A natural route gives natural flavor; synthesis gives artificial 4-Allylphenol, same molecule. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic 4-Allylphenol identical-to-natural.

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as 4-ALLYLPHENOL under CAS 501-92-8 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.