Flavor ingredient regulatory record

4-Propenylphenol

4-Propenylphenol is a phenol in the floral family, FEMA GRAS under FEMA number 4062 (CAS 539-12-8). Its odor is sweet, floral, spicy, herbal.

FEMA
4062
CAS
539-12-8
JECFA
2012
EU FL
04.097
Formula
C9H10O

GRAS status: FEMA GRAS, publication 21. Recorded by FDA in the Substances Added to Food inventory under CAS 85960-81-2.

Structure

2D structure of 4-Propenylphenol
Structure of 4-Propenylphenol, C9H10O. Drawn from the canonical SMILES.

Identity

IUPAC name 4-prop-1-enylphenol
CAS number 539-12-8
FEMA number 4062
Molecular formula C9H10O
Molecular weight 134.18 g/mol
SMILES CC=Cc1ccc(O)cc1
InChIKey UMFCIIBZHQXRCJ-UHFFFAOYSA-N
PubChem CID 415627
FDA UNII 34CGE324DZ
EPA DTXSID DTXSID101006553
Chemical class Phenol
Boiling point 109 °C
Flash point 38 °C

Also known as: Phenol, 4-(1-propen-1-yl)-, Phenol, p-propenyl-, Phenol, 4-(1-propenyl)-, 4-(1-Propen-1-yl)phenol, p-Anol, Isochavicol, p-Propenylphenol, p-Hydroxypropenylbenzene, 4-Hydroxypropenylbenzene, 4-(1-Propenyl)phenol, Anol, (4-Hydroxyphenyl)-1-propene.

Can 4-Propenylphenol be labeled natural?

Since 4-Propenylphenol is found in nature, US labeling follows how it was obtained: natural flavor from a natural source and a natural process, artificial when 4-Propenylphenol is synthesized. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.

United States
Natural or artificial, by process
European Union and UK
Natural only from natural material
Mercosur and Mexico
Natural or identical-to-natural

How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.

Regulatory status, with citations

United States

4-Propenylphenol is FEMA GRAS under FEMA number 4062. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 04.097, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.

JECFA (WHO / FAO)

JECFA number 2012, evaluated at the 73rd meeting in 2010. No safety concern at current levels of intake when used as a flavouring agent.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

Odor and taste

Odor: Sweet, floral, spicy, herbal.

Where it is used

4-Propenylphenol is used in beverage, confection, flavoring agents and cosmetics, typically as a floral note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to 4-Propenylphenol by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
p-Propylphenol364990%In nature
4-Allylphenol407587%In nature
3-Phenylpropionaldehyde288780%In nature
Cinnamaldehyde228678%In nature
4-Ethylbenzaldehyde375677%In nature

More phenols in this index

Anisole · 2-Ethoxy-4-(hydroxymethyl)phenol · 1,2-Dimethoxybenzene · Isoeugenol · 4-Allylphenol · 2-Methoxy-4-vinylphenol

4-Propenylphenol FAQ

Is 4-Propenylphenol FEMA GRAS?

Yes. The FEMA Expert Panel lists 4-Propenylphenol as GRAS under FEMA number 4062. It is also codified at 21 CFR 172.515.

What are the FEMA and CAS numbers for 4-Propenylphenol?

4-Propenylphenol is FEMA 4062, CAS 539-12-8. FEMA files it in the floral flavor category.

Does 4-Propenylphenol count as natural in the US and the EU?

4-Propenylphenol occurs in nature, so the label depends on the route: 4-Propenylphenol won from a natural source by a physical, enzymatic or microbiological process is natural flavor in the United States, and synthesized 4-Propenylphenol is artificial. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic 4-Propenylphenol identical-to-natural.

Is 4-Propenylphenol on the EU Union List?

4-Propenylphenol is on the EU Union List of flavouring substances as FL 04.097 (Annex I Part A) under Regulation 1334/2008.

Has JECFA evaluated 4-Propenylphenol?

Yes. JECFA number 2012, evaluated at the 73rd meeting in 2010. Conclusion: No safety concern at current levels of intake when used as a flavouring agent.

How is 4-Propenylphenol described, and where does it show up?

Flavorists describe 4-Propenylphenol as sweet, floral, spicy, herbal. It is used in beverage, confection, flavoring agents and cosmetics.

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as (Z)-4-PROPENYLPHENOL under CAS 85960-81-2 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.