Flavor ingredient regulatory record

2-Methylfuran

2-Methylfuran is a furan in the fruity family, FEMA GRAS under FEMA number 4179 (CAS 534-22-5). Its odor is sweet, nutty, caramel, roasted, coffee.

FEMA
4179
CAS
534-22-5
JECFA
1487
Formula
C5H6O

GRAS status: FEMA GRAS, publication 22. Recorded by FDA in the Substances Added to Food inventory under CAS 534-22-5.

Structure

2D structure of 2-Methylfuran
Structure of 2-Methylfuran, C5H6O. Drawn from the canonical SMILES.

Identity

IUPAC name 2-methylfuran
CAS number 534-22-5
FEMA number 4179
Molecular formula C5H6O
Molecular weight 82.1 g/mol
SMILES Cc1ccco1
InChIKey VQKFNUFAXTZWDK-UHFFFAOYSA-N
PubChem CID 10797
FDA UNII 51O3BGW3F2
EPA DTXSID DTXSID9025611
Chemical class Furan
Boiling point 64 °C
Flash point -30 °C

Also known as: Furan, 2-methyl-, α-Methylfuran, Silvan, Sylvan, 5-Methylfuran, NSC 3707, NSC 5211, silvan, sylvan, 2-methyl furan, furan, 2-methyl-, 5-methylfuran.

Can 2-Methylfuran be labeled natural?

The process decides for 2-Methylfuran. It occurs in nature, so a natural-source, natural-process material is natural flavor in the US and synthetic 2-Methylfuran is artificial. The EU and UK grant the natural claim only to that natural route; Mercosur and Mexico call synthetic material identical-to-natural.

United States
Natural or artificial, by process
European Union and UK
Natural only from natural material
Mercosur and Mexico
Natural or identical-to-natural

How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.

Regulatory status, with citations

United States

2-Methylfuran is FEMA GRAS under FEMA number 4179. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

2-Methylfuran was on the Union List of flavouring substances as FL 13.030 when Regulation (EU) 872/2012 adopted the list, and the entry has since been withdrawn. It does not appear in the current consolidated text of Regulation (EC) 1334/2008. Check the amending regulations for the conditions that applied to existing stock, and treat EU or UK use as closed unless another route covers it.

JECFA (WHO / FAO)

JECFA number 1487, evaluated at the 65th meeting in 2005.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

TSCA Inventory status

A flavor ingredient is also an industrial chemical. 2-Methylfuran appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 534-22-5, where EPA names it Furan, 2-methyl-.

Active in US commerce

EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.

EPA publishes no regulatory flags on this listing. What the flags mean.

From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.

Odor and taste

Odor: Sweet, nutty, caramel, roasted, coffee.

Where it is used

2-Methylfuran is used in beverage, confection, bakery and snacks, typically as a fruity note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to 2-Methylfuran by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
5-Methyl-3(2H)-furanone417687%In nature
2-Methylthiophene492883%In nature
2-Methyl-3-furanthiol318879%In nature
2-Pyridine296677%In nature
2-Ethylfuran367377%In nature

More furans in this index

3-Methyl-2-(3-methylbut-2-enyl)-furan · Furfural · 2-Ethylfuran · 2-Methyl-5-(methylthio)furan · Ethyl furfuryl ether · 5-Methylfurfural

2-Methylfuran FAQ

Is 2-Methylfuran FEMA GRAS?

Yes. The FEMA Expert Panel lists 2-Methylfuran as GRAS under FEMA number 4179. The Code of Federal Regulations lists it at 21 CFR 172.515.

What are the FEMA and CAS numbers for 2-Methylfuran?

2-Methylfuran is FEMA 4179, CAS 534-22-5. Its flavor category is fruity.

How is 2-Methylfuran described, and where does it show up?

Flavorists describe 2-Methylfuran as sweet, nutty, caramel, roasted, coffee. It is used in beverage, confection, bakery and snacks.

What did JECFA conclude about 2-Methylfuran?

JECFA evaluated 2-Methylfuran at the 65th meeting in 2005 under JECFA number 1487.

Is 2-Methylfuran approved in the EU?

No EU FL number is on file for 2-Methylfuran. It has a JECFA evaluation (JECFA 1487), which the EU list draws on, but the Union List entry itself should be confirmed before EU use.

Does 2-Methylfuran count as natural in the US and the EU?

Nature makes 2-Methylfuran, which is why the US label turns on process. A natural route gives natural flavor; synthesis gives artificial 2-Methylfuran, same molecule. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as 2-METHYLFURAN under CAS 534-22-5 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.