Flavor ingredient regulatory record
2-trans-4-cis-7-cis-Tridecatrienal
2-trans-4-cis-7-cis-Tridecatrienal is an aldehyde in the fruity family, FEMA GRAS under FEMA number 3638 (CAS 13552-96-0). Its odor is green, fruity, cucumber, melon, fresh.
- FEMA
- 3638
- CAS
- 13552-96-0
- JECFA
- 1198
- EU FL
- 05.064
- Formula
- C13H20O
- EC
- 236-936-3
GRAS status: FEMA GRAS, publication 12. Recorded by FDA in the Substances Added to Food inventory under CAS 13552-96-0.
Structure
Identity
Also known as: 2,4,7-Tridecatrienal, (2E,4Z,7Z)-, 2,4,7-Tridecatrienal, (E,Z,Z)-, (2E,4Z,7Z)-2,4,7-Tridecatrienal, 2-trans,4-cis,7-cis-Tridecatrienal, (E,Z,Z)-2,4,7-Tridecatrienal, 2E,4Z,7Z-Tridecatrienal, (e,z,z)-trideca-2,4,7-trienal, (e,z,z)-2,4,7-tridecatrienal, 2-trans,4-cis,7-cis-tridecatrienal, 2,4,7-tridecatrienal, (e,z,z)-, 2,4,7-tridecatrienal, (2e,4z,7z)-, 2,4,7-tridecatrienal, trans,cis,cis-.
Can 2-trans-4-cis-7-cis-Tridecatrienal be labeled natural?
Since 2-trans-4-cis-7-cis-Tridecatrienal is found in nature, US labeling follows how it was obtained: natural flavor from a natural source and a natural process, artificial when 2-trans-4-cis-7-cis-Tridecatrienal is synthesized. The EU and UK grant the natural claim only to that natural route; Mercosur and Mexico call synthetic material identical-to-natural.
- United States
- Natural or artificial, by process
- European Union and UK
- Natural only from natural material
- Mercosur and Mexico
- Natural or identical-to-natural
How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.
Regulatory status, with citations
United States
2-trans-4-cis-7-cis-Tridecatrienal is FEMA GRAS under FEMA number 3638. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
Listed on the Union List of flavouring substances as FL 05.064, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.
Purity. At least 71 %; secondary components 14 % 4-cis-7-cis-tridecadienol; 6 % 3-cis-7-cis- tridecadienol; 5 % 2-trans-7-cis-tridecadienal; 3 % 2-trans-4-trans-7-cis-tridecatrienal
JECFA (WHO / FAO)
JECFA number 1198, evaluated at the 73rd meeting in 2010. no safety concern at current levels of intake.
Other US flags
Not on the California Proposition 65 list.
Odor and taste
Odor: Green, fruity, cucumber, melon, fresh.
Where it is used
2-trans-4-cis-7-cis-Tridecatrienal is used in beverage, fruit flavors, confection and savory dishes, typically as a fruity note.
Structurally similar flavor ingredients
Flavor ingredients with a GRAS determination closest to 2-trans-4-cis-7-cis-Tridecatrienal by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.
| Material | FEMA | Similarity | Occurrence |
|---|---|---|---|
| 2-trans-6-cis-Dodecadienal | 3637 | 97% | In nature |
| (2E, 4E)-undeca-2,4-dienal | 3422 | 95% | In nature |
| 2-trans,4-trans-Decadienal | 3135 | 88% | In nature |
| Dodec-2-(trans)-enal | 2402 | 83% | In nature |
| (E)-4-Undecenal | 4672 | 82% | Not determined |
More aldehydes in this index
2-trans,4-trans-Decadienal · 4-Ethylbenzaldehyde · 2-Methyl-3-(p-isopropylphenyl)propionaldehyde · Butyraldehyde · Heptanal · cis-5-Octenal
2-trans-4-cis-7-cis-Tridecatrienal FAQ
Is 2-trans-4-cis-7-cis-Tridecatrienal on the FEMA GRAS list?
It is. FEMA number 3638 covers 2-trans-4-cis-7-cis-Tridecatrienal. It is also codified at 21 CFR 172.515.
What is the FEMA number for 2-trans-4-cis-7-cis-Tridecatrienal?
The FEMA number for 2-trans-4-cis-7-cis-Tridecatrienal is 3638 and its CAS registry number is 13552-96-0. FEMA files it in the fruity flavor category.
Is 2-trans-4-cis-7-cis-Tridecatrienal natural or artificial?
2-trans-4-cis-7-cis-Tridecatrienal occurs in nature, so the label depends on the route: 2-trans-4-cis-7-cis-Tridecatrienal won from a natural source by a physical, enzymatic or microbiological process is natural flavor in the United States, and synthesized 2-trans-4-cis-7-cis-Tridecatrienal is artificial. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.
Is 2-trans-4-cis-7-cis-Tridecatrienal approved in the EU?
2-trans-4-cis-7-cis-Tridecatrienal is on the EU Union List of flavouring substances as FL 05.064 (Annex I Part A) under Regulation 1334/2008.
Has JECFA evaluated 2-trans-4-cis-7-cis-Tridecatrienal?
Yes. JECFA number 1198, evaluated at the 73rd meeting in 2010. Conclusion: no safety concern at current levels of intake.
What is 2-trans-4-cis-7-cis-Tridecatrienal used for?
2-trans-4-cis-7-cis-Tridecatrienal is described as green, fruity, cucumber, melon, fresh. It shows up in beverage, fruit flavors, confection and savory dishes.
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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as 2-TRANS,4-CIS,7-CIS-TRIDECATRIENAL under CAS 13552-96-0 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.