Flavor ingredient regulatory record

3-[(2-Methyl-3-furyl)thio]-2-butanone

3-[(2-Methyl-3-furyl)thio]-2-butanone is a thioether in the fruity family, FEMA GRAS under FEMA number 4056 (CAS 61295-44-1). Its odor is sweet, fruity, nutty, caramel, roasted.

FEMA
4056
CAS
61295-44-1
JECFA
1525
EU FL
13.190
Formula
C9H12O2S

GRAS status: FEMA GRAS, publication 21. Recorded by FDA in the Substances Added to Food inventory under CAS 61295-44-1.

Structure

2D structure of 3-[(2-Methyl-3-furyl)thio]-2-butanone
Structure of 3-[(2-Methyl-3-furyl)thio]-2-butanone, C9H12O2S. Drawn from the canonical SMILES.

Identity

IUPAC name 3-(2-methylfuran-3-yl)sulfanylbutan-2-one
CAS number 61295-44-1
FEMA number 4056
Molecular formula C9H12O2S
Molecular weight 184.26 g/mol
SMILES CC(=O)C(C)Sc1ccoc1C
InChIKey AOEYNSLUBHRZPA-UHFFFAOYSA-N
PubChem CID 12980878
FDA UNII 9R89X7164W
EPA DTXSID DTXSID90976780
Chemical class Thioether
Boiling point 70 °C
Flash point 96 °C

Also known as: 2-Butanone, 3-[(2-methyl-3-furanyl)thio]-, 3-[(2-Methyl-3-furanyl)thio]-2-butanone, 3-((2-Methyl-3-furyl)thio)-2-butanone, 3-((2-methyl-3-furyl)thio)-2-butanone, 3-(2-methyl-3-furylthio)-2-butanone, 3-((2-methyl-3-furyl)sulfanyl)-2-butanone, 2-butanone, 3-((2-methyl-3-furanyl)thio)-, 3-((2-methyl-3-furanyl)sulfanyl)-2-butanone, 3-((2-methyl-3-furyl)sulfanyl)butan-2-one, 3-[(2-methylfuran-3-yl)sulfanyl]butan-2-one, 3-[(2-methyl-3-furyl)sulfanyl]-2-butanone, 3-((2-methylfuran-3-yl)sulfanyl)butan-2-one.

Can 3-[(2-Methyl-3-furyl)thio]-2-butanone be labeled natural?

Nature occurrence: Not yet found in nature (provisional).

Nature occurrence has not been settled for this substance, so the natural or artificial class is not stated here. The FEMA GRAS status does not depend on it.

Regulatory status, with citations

United States

3-[(2-Methyl-3-furyl)thio]-2-butanone is FEMA GRAS under FEMA number 4056. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 13.190, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.

JECFA (WHO / FAO)

JECFA number 1525, evaluated at the 86th meeting in 2018. No safety concern at current levels of intake when used as a flavouring agent.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

Odor and taste

Odor: Sweet, fruity, nutty, caramel, roasted.

Taste: Sweet, savory, slightly nutty.

Where it is used

3-[(2-Methyl-3-furyl)thio]-2-butanone is used in beverage, confection, savory dishes and snacks, typically as a fruity note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to 3-[(2-Methyl-3-furyl)thio]-2-butanone by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
S-Furfuryl thioacetate316276%In nature
2-Ethanethoic acid, S-(2-methyl-3-furanyl) ester397374%Not determined
3-[(2-Methyl-3-furyl)thio]-4-heptanone357074%In nature
3-[(2-Methyl-3-furyl)thio]butanal450171%Not determined
S-Furfuryl thiopropionate334769%In nature

More thioethers in this index

3-[(2-Methyl-3-furyl)thio]-4-heptanone · 4-[(2-Methyl-3-furyl)thio]-5-nonanone · bis-(2-Methyl-3-furyl) disulfide · Propyl furfuryl disulfide

3-[(2-Methyl-3-furyl)thio]-2-butanone FAQ

Is 3-[(2-Methyl-3-furyl)thio]-2-butanone FEMA GRAS?

Yes. The FEMA Expert Panel lists 3-[(2-Methyl-3-furyl)thio]-2-butanone as GRAS under FEMA number 4056. It is also codified at 21 CFR 172.515.

What are the FEMA and CAS numbers for 3-[(2-Methyl-3-furyl)thio]-2-butanone?

3-[(2-Methyl-3-furyl)thio]-2-butanone is FEMA 4056, CAS 61295-44-1. FEMA files it in the fruity flavor category.

Is 3-[(2-Methyl-3-furyl)thio]-2-butanone on the EU Union List?

3-[(2-Methyl-3-furyl)thio]-2-butanone is on the EU Union List of flavouring substances as FL 13.190 (Annex I Part A) under Regulation 1334/2008.

Has JECFA evaluated 3-[(2-Methyl-3-furyl)thio]-2-butanone?

Yes. JECFA number 1525, evaluated at the 86th meeting in 2018. Conclusion: No safety concern at current levels of intake when used as a flavouring agent.

How is 3-[(2-Methyl-3-furyl)thio]-2-butanone described, and where does it show up?

Flavorists describe 3-[(2-Methyl-3-furyl)thio]-2-butanone as sweet, fruity, nutty, caramel, roasted. On the palate it is sweet, savory, slightly nutty. It is used in beverage, confection, savory dishes and snacks.

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as (+/-)-3-[(2-METHYL-3-FURYL)THIO]-2-BUTANONE under CAS 61295-44-1 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.