Flavor ingredient regulatory record

Propyl furfuryl disulfide

Propyl furfuryl disulfide is a thioether in the savory family, FEMA GRAS under FEMA number 3979 (CAS 252736-36-0). Its odor is garlic, onion, savory, sulfurous.

FEMA
3979
CAS
252736-36-0
JECFA
1079
EU FL
13.197
Formula
C8H12OS2

GRAS status: FEMA GRAS, publication 20. Recorded by FDA in the Substances Added to Food inventory under CAS 252736-36-0.

Structure

2D structure of Propyl furfuryl disulfide
Structure of Propyl furfuryl disulfide, C8H12OS2. Drawn from the canonical SMILES.

Identity

IUPAC name 2-[(propyldisulfanyl)methyl]furan
CAS number 252736-36-0
FEMA number 3979
Molecular formula C8H12OS2
Molecular weight 188.32 g/mol
SMILES CCCSSCc1ccco1
InChIKey YCXWJNAAXGVFED-UHFFFAOYSA-N
PubChem CID 15743318
FDA UNII HVD52TXC64
EPA DTXSID DTXSID101020040
Chemical class Thioether
Boiling point -123 °C
Flash point 91 °C

Also known as: Furan, 2-[(propyldithio)methyl]-, 2-[(Propyldithio)methyl]furan, furfuryl propyl disulfide, 2-[(propyldisulfanyl)methyl]furan, furan, 2-((propyldithio)methyl)-, furfuryl propyl disulfide [fifh], furfuryl propyl disulfide [fhfi], 2-((propyldisulfanyl)methyl)furan, furfuryl propyl disulfide (fifh), furan,2-[(propyldithio)methyl]-, 2-[(propyldisulanyl)methyl]uran, 2-((propyldisulfaneyl)methyl)furan.

Can Propyl furfuryl disulfide be labeled natural?

Nature occurrence: Not yet found in nature (provisional).

Nature occurrence has not been settled for this substance, so the natural or artificial class is not stated here. The FEMA GRAS status does not depend on it.

Regulatory status, with citations

United States

Propyl furfuryl disulfide is FEMA GRAS under FEMA number 3979. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 13.197, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.

JECFA (WHO / FAO)

JECFA number 1079, evaluated at the 59th meeting in 2003. no safety concern at current levels of intake.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

Odor and taste

Odor: Garlic, onion, savory, sulfurous.

Where it is used

Propyl furfuryl disulfide is used in savory snacks, sauces, seasonings and meat products, typically as a savory note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to Propyl furfuryl disulfide by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
2,2'-(Dithiodimethylene)difuran314672%In nature
S-Furfuryl thiopropionate334765%In nature

More thioethers in this index

bis-(2-Methyl-3-furyl) disulfide · 3-[(2-Methyl-3-furyl)thio]-4-heptanone · 4-[(2-Methyl-3-furyl)thio]-5-nonanone · 3-[(2-Methyl-3-furyl)thio]-2-butanone

Propyl furfuryl disulfide FAQ

Does propyl furfuryl disulfide have FEMA GRAS status?

Propyl furfuryl disulfide holds FEMA GRAS status under FEMA number 3979. The Code of Federal Regulations lists it at 21 CFR 172.515.

How do I cite propyl furfuryl disulfide by FEMA or CAS number?

Cite propyl furfuryl disulfide as FEMA 3979 or CAS 252736-36-0; both point to the same entry. Its flavor category is savory.

What does propyl furfuryl disulfide smell and taste like, and where is it used?

The odor of propyl furfuryl disulfide is garlic, onion, savory, sulfurous. Typical uses are savory snacks, sauces, seasonings and meat products.

What did JECFA conclude about propyl furfuryl disulfide?

JECFA evaluated propyl furfuryl disulfide at the 59th meeting in 2003 under JECFA number 1079. The panel concluded: no safety concern at current levels of intake.

Can propyl furfuryl disulfide be used in the EU and UK?

Yes. FL 13.197 is the Union List entry for propyl furfuryl disulfide, annex I Part A, under Regulation 1334/2008, and the UK keeps the same list.

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as FURFURYL PROPYL DISULFIDE under CAS 252736-36-0 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.