Flavor ingredient regulatory record
cis-Hexenyl tiglate
cis-Hexenyl tiglate is an ester in the fruity family, FEMA GRAS under FEMA number 3931 (CAS 67883-79-8). Its odor is sweet, fruity, green, floral, apple.
- FEMA
- 3931
- CAS
- 67883-79-8
- JECFA
- 1277
- EU FL
- 09.559
- Formula
- C11H18O2
- EC
- 267-554-5
GRAS status: FEMA GRAS, publication 19. Recorded by FDA in the Substances Added to Food inventory under CAS 67883-79-8.
Structure
Identity
Also known as: 2-Butenoic acid, 2-methyl-, (3Z)-3-hexen-1-yl ester, (2E)-, 2-Butenoic acid, 2-methyl-, 3-hexenyl ester, (E,Z)-, 2-Butenoic acid, 2-methyl-, (3Z)-3-hexenyl ester, (2E)-, cis-3-Hexenyl tiglate, Z-3-Hexenyl tiglate, (Z)-3-Hexenyl tiglate, (3Z)-Hexenyl tiglate, cis-3-hexenyl tiglate, (3z)-hex-3-en-1-yl (2e)-2-methylbut-2-enoate, hexenyl tiglate, (3z)-, (z)-3-hexenyl tiglate, (z)-3-hexenyl 2-methylcrotonate.
Can cis-Hexenyl tiglate be labeled natural?
The process decides for cis-Hexenyl tiglate. It occurs in nature, so a natural-source, natural-process material is natural flavor in the US and synthetic cis-Hexenyl tiglate is artificial. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.
- United States
- Natural or artificial, by process
- European Union and UK
- Natural only from natural material
- Mercosur and Mexico
- Natural or identical-to-natural
How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.
Regulatory status, with citations
United States
cis-Hexenyl tiglate is FEMA GRAS under FEMA number 3931. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
Listed on the Union List of flavouring substances as FL 09.559, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.
JECFA (WHO / FAO)
JECFA number 1277, evaluated at the 61st meeting in 2003. No safety concern at current levels of intake when used as a flavouring agent.
Other US flags
Not on the California Proposition 65 list.
TSCA Inventory status
A flavor ingredient is also an industrial chemical. cis-Hexenyl tiglate appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 67883-79-8, where EPA names it 2-Butenoic acid, 2-methyl-, (3Z)-3-hexen-1-yl ester, (2E)-.
Active in US commerce
EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.
EPA publishes no regulatory flags on this listing. What the flags mean.
From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.
Odor and taste
Odor: Sweet, fruity, green, floral, apple.
Where it is used
cis-Hexenyl tiglate is used in beverage, confection, fruit flavors, baked goods and desserts, typically as a fruity note.
More esters in this index
Sodium 2-(4-methoxyphenoxy)propanoate · Ethyl 3-(methylthio)-trans-2-propenoate · Ethyl sorbate · Ethyl formate · Menthyl valerate · Methyl 3-hydroxyhexanoate
cis-Hexenyl tiglate FAQ
Does cis-Hexenyl tiglate have FEMA GRAS status?
cis-Hexenyl tiglate holds FEMA GRAS status under FEMA number 3931. The Code of Federal Regulations lists it at 21 CFR 172.515.
How do I cite cis-Hexenyl tiglate by FEMA or CAS number?
Cite cis-Hexenyl tiglate as FEMA 3931 or CAS 67883-79-8; both point to the same entry. Its flavor category is fruity.
What does cis-Hexenyl tiglate smell and taste like, and where is it used?
The odor of cis-Hexenyl tiglate is sweet, fruity, green, floral, apple. Typical uses are beverage, confection, fruit flavors, baked goods and desserts.
What did JECFA conclude about cis-Hexenyl tiglate?
JECFA evaluated cis-Hexenyl tiglate at the 61st meeting in 2003 under JECFA number 1277. The panel concluded: No safety concern at current levels of intake when used as a flavouring agent.
Can cis-Hexenyl tiglate be used in the EU and UK?
Yes. FL 09.559 is the Union List entry for cis-Hexenyl tiglate, annex I Part A, under Regulation 1334/2008, and the UK keeps the same list.
Can cis-Hexenyl tiglate be labeled a natural flavor?
Nature makes cis-Hexenyl tiglate, which is why the US label turns on process. A natural route gives natural flavor; synthesis gives artificial cis-Hexenyl tiglate, same molecule. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic cis-Hexenyl tiglate identical-to-natural.
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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as (Z)-3-HEXENYL(E)-2-METHYL-2-BUTENOATE under CAS 67883-79-8 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.