Flavor ingredient regulatory record

Dihydro-beta-ionol

Dihydro-beta-ionol is an alcohol in the fruity family, FEMA GRAS under FEMA number 3627 (CAS 3293-47-8). Its odor is sweet, floral, fruity, berry, woody.

FEMA
3627
CAS
3293-47-8
JECFA
395
EU FL
02.107
Formula
C13H24O
EC
221-957-2

GRAS status: FEMA GRAS, publication 12. Recorded by FDA in the Substances Added to Food inventory under CAS 3293-47-8.

Structure

2D structure of Dihydro-beta-ionol
Structure of Dihydro-beta-ionol, C13H24O. Drawn from the canonical SMILES.

Identity

IUPAC name 4-(2,6,6-trimethylcyclohexen-1-yl)butan-2-ol
CAS number 3293-47-8
FEMA number 3627
Molecular formula C13H24O
Molecular weight 196.33 g/mol
SMILES CC1=C(CCC(C)O)C(C)(C)CCC1
InChIKey VSYLEWGIVLSDIY-UHFFFAOYSA-N
PubChem CID 579336
EC number 221-957-2
FDA UNII S3T0WG30TW
EPA DTXSID DTXSID90863146
Chemical class Alcohol
Boiling point 97 °C
Flash point 32 °C

Also known as: 1-Cyclohexene-1-propanol, α,2,6,6-tetramethyl-, α,2,6,6-Tetramethyl-1-cyclohexene-1-propanol, Dihydro-β-ionol, 4-(2,6,6-Trimethyl-1-cyclohexenyl)-2-butanol, 7,8-Dihydro-β-ionol, 4-(2,6,6-Trimethylcyclohex-1-en-1-yl)butan-2-ol, alpha,2,6,6-tetramethylcyclohexene-1-propan-1-ol, 4-(2,6,6-trimethyl-1-cyclohexenyl)butan-2-ol, 4-(2,6,6-trimethylcyclohexen-1-yl)butan-2-ol, 4-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2-butanol, alpha,2,6,6-tetramethyl-1-cyclohexene-1-propanol, 1-cyclohexene-1-propanol, alpha,2,6,6-tetramethyl-.

Can Dihydro-beta-ionol be labeled natural?

The process decides for dihydro-beta-ionol. It occurs in nature, so a natural-source, natural-process material is natural flavor in the US and synthetic dihydro-beta-ionol is artificial. The EU and UK grant the natural claim only to that natural route; Mercosur and Mexico call synthetic material identical-to-natural.

United States
Natural or artificial, by process
European Union and UK
Natural only from natural material
Mercosur and Mexico
Natural or identical-to-natural

How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.

Regulatory status, with citations

United States

Dihydro-beta-ionol is FEMA GRAS under FEMA number 3627. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 02.107, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (JECFA). The UK retains the same list.

JECFA (WHO / FAO)

JECFA number 395, evaluated at the 51st meeting in 1998. no safety concern at current levels of intake.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

TSCA Inventory status

A flavor ingredient is also an industrial chemical. Dihydro-beta-ionol appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 3293-47-8, where EPA names it 1-Cyclohexene-1-propanol, .alpha.,2,6,6-tetramethyl-.

Active in US commerce

EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.

EPA publishes no regulatory flags on this listing. What the flags mean.

From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.

Odor and taste

Odor: Sweet, floral, fruity, berry, woody.

Where it is used

Dihydro-beta-ionol is used in beverage, confection, fragrance, flavoring and cosmetics, typically as a fruity note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to Dihydro-beta-ionol by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
beta-Ionol362593%In nature
Dihydro-beta-ionone362691%In nature
alpha-Ionol362491%In nature
Dihydro-alpha-ionone362887%In nature
Dehydrodihydroionone344784%In nature

More alcohols in this index

alpha,alpha-Dimethylphenethyl alcohol · (E,Z)-3,6-Nonadien-1-ol · 3-Octen-2-ol · 2-Methyl-4-phenyl-2-butanol · p,alpha-Dimethylbenzyl alcohol · cis-5-Octen-1-ol

Dihydro-beta-ionol FAQ

Is dihydro-beta-ionol FEMA GRAS?

Yes. The FEMA Expert Panel lists dihydro-beta-ionol as GRAS under FEMA number 3627. The Code of Federal Regulations lists it at 21 CFR 172.515.

What are the FEMA and CAS numbers for dihydro-beta-ionol?

Dihydro-beta-ionol is FEMA 3627, CAS 3293-47-8. Its flavor category is fruity.

How is dihydro-beta-ionol described, and where does it show up?

Flavorists describe dihydro-beta-ionol as sweet, floral, fruity, berry, woody. It is used in beverage, confection, fragrance, flavoring and cosmetics.

What did JECFA conclude about dihydro-beta-ionol?

JECFA evaluated dihydro-beta-ionol at the 51st meeting in 1998 under JECFA number 395. The panel concluded: no safety concern at current levels of intake.

Is dihydro-beta-ionol on the EU Union List?

Yes. FL 02.107 is the Union List entry for dihydro-beta-ionol, annex I Part A, under Regulation 1334/2008, and the UK keeps the same list.

Does dihydro-beta-ionol count as natural in the US and the EU?

Nature makes dihydro-beta-ionol, which is why the US label turns on process. A natural route gives natural flavor; synthesis gives artificial dihydro-beta-ionol, same molecule. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as DIHYDRO-BETA-IONOL under CAS 3293-47-8 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.