Flavor ingredient regulatory record

Disodium succinate

Disodium succinate is an acid in the savory family, FEMA GRAS under FEMA number 3277 (CAS 150-90-3). Its odor is umami, savory, slightly tangy, broth-like.

FEMA
3277
CAS
150-90-3
EU FL
08.113
Formula
C4H4Na2O4
EC
205-778-7

GRAS status: FEMA GRAS, publication 5. Recorded by FDA in the Substances Added to Food inventory under CAS 150-90-3.

Structure

2D structure of Disodium succinate
Structure of Disodium succinate, C4H4Na2O4. Drawn from the canonical SMILES.

Identity

IUPAC name disodium;butanedioate
CAS number 150-90-3
FEMA number 3277
Molecular formula C4H4Na2O4
Molecular weight 162.05 g/mol
SMILES O=C([O-])CCC(=O)[O-].[Na+].[Na+]
InChIKey ZDQYSKICYIVCPN-UHFFFAOYSA-L
PubChem CID 9020
EC number 205-778-7
FDA UNII V8ZGC8ISR3
EPA DTXSID DTXSID5059741
Chemical class Acid

Also known as: Butanedioic acid, sodium salt (1:2), Succinic acid, disodium salt, Butanedioic acid, disodium salt, Soduxin, Sodium succinate, SS 50, sodium succinate, disodium butanedioate, succinate sodium, sodium succinate anhydrous, butanedioic acid disodium salt, sodium succinate, anhydrous.

Can Disodium succinate be labeled natural?

Nature makes disodium succinate, which is why the US label turns on process. A natural route gives natural flavor; synthesis gives artificial disodium succinate, same molecule. The EU and UK grant the natural claim only to that natural route; Mercosur and Mexico call synthetic material identical-to-natural.

United States
Natural or artificial, by process
European Union and UK
Natural only from natural material
Mercosur and Mexico
Natural or identical-to-natural

How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.

Regulatory status, with citations

United States

Disodium succinate is FEMA GRAS under FEMA number 3277. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 08.113, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.

JECFA (WHO / FAO)

Disodium succinate has not been evaluated by JECFA as a flavouring agent, or no evaluation is on file.

Other US flags

Not on the California Proposition 65 list.

TSCA Inventory status

A flavor ingredient is also an industrial chemical. Disodium succinate appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 150-90-3, where EPA names it Butanedioic acid, sodium salt (1:2).

Active in US commerce

EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.

EPA publishes no regulatory flags on this listing. What the flags mean.

From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.

Odor and taste

Odor: Umami, savory, slightly tangy, broth-like.

Taste: Savory, umami, slightly salty.

Where it is used

Disodium succinate is used in seasoning, sauces, snack foods and prepared meals, typically as a savory note.

Disodium succinate FAQ

Does disodium succinate have FEMA GRAS status?

Disodium succinate holds FEMA GRAS status under FEMA number 3277. The Code of Federal Regulations lists it at 21 CFR 172.515.

How do I cite disodium succinate by FEMA or CAS number?

Cite disodium succinate as FEMA 3277 or CAS 150-90-3; both point to the same entry. Its flavor category is savory.

What does disodium succinate smell and taste like, and where is it used?

The odor of disodium succinate is umami, savory, slightly tangy, broth-like. On the palate it is savory, umami, slightly salty. Typical uses are seasoning, sauces, snack foods and prepared meals.

Can disodium succinate be used in the EU and UK?

Yes. FL 08.113 is the Union List entry for disodium succinate, annex I Part A, under Regulation 1334/2008, and the UK keeps the same list.

Can disodium succinate be labeled a natural flavor?

The process decides for disodium succinate. It occurs in nature, so a natural-source, natural-process material is natural flavor in the US and synthetic disodium succinate is artificial. The EU and UK grant the natural claim only to that natural route; Mercosur and Mexico call synthetic material identical-to-natural.

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as DISODIUM SUCCINATE under CAS 150-90-3 and carries its FEMA number. The inventory is searchable at FDA. FDA records its technical effect as flavor enhancer, flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.