Flavor ingredient regulatory record

(E,Z)-3,6-Nonadien-1-ol

(E,Z)-3,6-Nonadien-1-ol is an alcohol in the fruity family, FEMA GRAS under FEMA number 3884 (CAS 56805-23-3). Its odor is sweet, fruity, green, floral, herbaceous.

FEMA
3884
CAS
56805-23-3
JECFA
1284
EU FL
02.243
Formula
C9H16O

GRAS status: FEMA GRAS, publication 18. Recorded by FDA in the Substances Added to Food inventory under CAS 56805-23-3.

Structure

2D structure of (E,Z)-3,6-Nonadien-1-ol
Structure of (E,Z)-3,6-Nonadien-1-ol, C9H16O. Drawn from the canonical SMILES.

Identity

IUPAC name (3E,6Z)-nona-3,6-dien-1-ol
CAS number 56805-23-3
FEMA number 3884
Molecular formula C9H16O
Molecular weight 140.23 g/mol
SMILES CC/C=C\C/C=C/CCO
InChIKey PICGPEBVZGCYBV-WWVFNRLHSA-N
PubChem CID 44630408
FDA UNII O3WVF7PM5K
EPA DTXSID DTXSID40886204
Chemical class Alcohol
Boiling point 73 °C
Flash point 19 °C

Also known as: 3,6-Nonadien-1-ol, (3E,6Z)-, 3,6-Nonadien-1-ol, (E,Z)-, (3E,6Z)-3,6-Nonadien-1-ol, trans,cis-3,6-Nonadien-1-ol, (3E,6Z)-3,6-Nonadienol, trans,cis-3,6-nonadien-1-ol, (3e,6z)-3,6-nonadien-1-ol, 3,6-nonadien-1-ol, (3e,6z)-, (3e,6z)-nona-3,6-dien-1-ol, 3,6-nonadien-1-ol, (e,z)-, 3,6-nonadien-1-ol, trans,cis-, (e)-3,(z)-6-nonadien-1-ol.

Can (E,Z)-3,6-Nonadien-1-ol be labeled natural?

(E,Z)-3,6-Nonadien-1-ol occurs in nature, so the label depends on the route: (E,Z)-3,6-Nonadien-1-ol won from a natural source by a physical, enzymatic or microbiological process is natural flavor in the United States, and synthesized (E,Z)-3,6-Nonadien-1-ol is artificial. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic (E,Z)-3,6-Nonadien-1-ol identical-to-natural.

United States
Natural or artificial, by process
European Union and UK
Natural only from natural material
Mercosur and Mexico
Natural or identical-to-natural

How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.

Regulatory status, with citations

United States

(E,Z)-3,6-Nonadien-1-ol is FEMA GRAS under FEMA number 3884. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 02.243, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.

Purity. At least 92%; secondary component 6% (E,E)-3,6-nonadien-1-ol

JECFA (WHO / FAO)

JECFA number 1284, evaluated at the 61st meeting in 2003. no safety concern at current levels of intake.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

TSCA Inventory status

A flavor ingredient is also an industrial chemical. (E,Z)-3,6-Nonadien-1-ol appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 56805-23-3, where EPA names it 3,6-Nonadien-1-ol, (3E,6Z)-.

Active in US commerce

EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.

EPA regulatory flags

Flag EPA definition What it obliges
PMN Indicates a commenced PMN substance. Nothing new. The substance already went through premanufacture review and someone filed a notice of commencement, which is why it is on the Inventory. It is an existing chemical and needs no new premanufacture notice. Read more

PMN does not establish: The flag records how the substance arrived, not what may be done with it. Check the flags beside it.

From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.

Odor and taste

Odor: Sweet, fruity, green, floral, herbaceous.

Where it is used

(E,Z)-3,6-Nonadien-1-ol is used in beverage, confection, fruit flavors and flavoring agents, typically as a fruity note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to (E,Z)-3,6-Nonadien-1-ol by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
(Z,Z)-3,6-Nonadien-1-ol3885100%In nature
2,6-Nonadien-1-ol278099%In nature
2,4-Nonadien-1-ol395195%In nature
trans-3-Nonen-1-ol460595%In nature
cis-3-Nonen-1-ol441293%In nature

More alcohols in this index

3-Octanol · (E)- and (Z)-2,4,8-Trimethyl-3,7-nonadien-2-ol · 4-Hexen-1-ol · (E,E)-2,4-Decadien-1-ol · 2-Ethyl-1-hexanol · 2,4-Nonadien-1-ol

(E,Z)-3,6-Nonadien-1-ol FAQ

Is (E,Z)-3,6-Nonadien-1-ol on the FEMA GRAS list?

It is. FEMA number 3884 covers (E,Z)-3,6-Nonadien-1-ol. It is also codified at 21 CFR 172.515.

What is the FEMA number for (E,Z)-3,6-Nonadien-1-ol?

The FEMA number for (E,Z)-3,6-Nonadien-1-ol is 3884 and its CAS registry number is 56805-23-3. FEMA files it in the fruity flavor category.

Is (E,Z)-3,6-Nonadien-1-ol natural or artificial?

Since (E,Z)-3,6-Nonadien-1-ol is found in nature, US labeling follows how it was obtained: natural flavor from a natural source and a natural process, artificial when (E,Z)-3,6-Nonadien-1-ol is synthesized. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic (E,Z)-3,6-Nonadien-1-ol identical-to-natural.

Is (E,Z)-3,6-Nonadien-1-ol approved in the EU?

(E,Z)-3,6-Nonadien-1-ol is on the EU Union List of flavouring substances as FL 02.243 (Annex I Part A) under Regulation 1334/2008.

Has JECFA evaluated (E,Z)-3,6-Nonadien-1-ol?

Yes. JECFA number 1284, evaluated at the 61st meeting in 2003. Conclusion: no safety concern at current levels of intake.

What is (E,Z)-3,6-Nonadien-1-ol used for?

(E,Z)-3,6-Nonadien-1-ol is described as sweet, fruity, green, floral, herbaceous. It shows up in beverage, confection, fruit flavors and flavoring agents.

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as (E)-3-(Z)-6-NONADIEN-1-OL under CAS 56805-23-3 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.