Flavor ingredient regulatory record

cis-3-Nonen-1-ol

cis-3-Nonen-1-ol is an alcohol in the fruity family, FEMA GRAS under FEMA number 4412 (CAS 10340-23-5). Its odor is sweet, fruity, green, floral, herbaceous.

FEMA
4412
CAS
10340-23-5
JECFA
2177
EU FL
02.234
Formula
C9H18O
EC
233-735-2

GRAS status: FEMA GRAS, publication 23. Recorded by FDA in the Substances Added to Food inventory under CAS 10340-23-5.

Structure

2D structure of cis-3-Nonen-1-ol
Structure of cis-3-Nonen-1-ol, C9H18O. Drawn from the canonical SMILES.

Identity

IUPAC name (Z)-non-3-en-1-ol
CAS number 10340-23-5
FEMA number 4412
Molecular formula C9H18O
Molecular weight 142.24 g/mol
SMILES CCCCC/C=C\CCO
InChIKey IFTBJDZSLBRRMC-SREVYHEPSA-N
PubChem CID 5364631
EC number 233-735-2
FDA UNII W8G7341QJ8
EPA DTXSID DTXSID60884464
Chemical class Alcohol
Boiling point 103 °C
Flash point 35 °C

Also known as: 3-Nonen-1-ol, (3Z)-, 3-Nonen-1-ol, (Z)-, (3Z)-3-Nonen-1-ol, cis-3-Nonenol, (Z)-3-Nonen-1-ol, 3(Z)-Nonenol, (3Z)-Non-3-en-1-ol, (z)-non-3-en-1-ol, (z)-3-nonen-1-ol, 3-nonen-1-ol, (3z)-, (z)-3-nonenol, (z)-nonenol.

Can cis-3-Nonen-1-ol be labeled natural?

cis-3-Nonen-1-ol occurs in nature, so the label depends on the route: cis-3-Nonen-1-ol won from a natural source by a physical, enzymatic or microbiological process is natural flavor in the United States, and synthesized cis-3-Nonen-1-ol is artificial. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic cis-3-Nonen-1-ol identical-to-natural.

United States
Natural or artificial, by process
European Union and UK
Natural only from natural material
Mercosur and Mexico
Natural or identical-to-natural

How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.

Regulatory status, with citations

United States

cis-3-Nonen-1-ol is FEMA GRAS under FEMA number 4412. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 02.234, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.

JECFA (WHO / FAO)

JECFA number 2177, evaluated at the 76th meeting in 2012. No safety concern at current levels of intake when used as a flavouring agent.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

TSCA Inventory status

A flavor ingredient is also an industrial chemical. cis-3-Nonen-1-ol appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 10340-23-5, where EPA names it 3-Nonen-1-ol, (3Z)-.

Active in US commerce

EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.

EPA publishes no regulatory flags on this listing. What the flags mean.

From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.

Odor and taste

Odor: Sweet, fruity, green, floral, herbaceous.

Where it is used

cis-3-Nonen-1-ol is used in beverage, confection, fruit flavors, bakery and dairy, typically as a fruity note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to cis-3-Nonen-1-ol by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
trans-3-Nonen-1-ol4605100%In nature
cis-3-Octen-1-ol346798%In nature
cis-4-Decenol434998%In nature
cis-2-Octenol461596%In nature
2-Octen-1-ol388796%In nature

More alcohols in this index

(Z)-4-Hepten-1-ol · trans-2-Tridecenol · 2,4-Heptadien-1-ol · Furfuryl alcohol · cis-4-Decenol · 2-Hexen-1-ol

cis-3-Nonen-1-ol FAQ

Is cis-3-Nonen-1-ol on the FEMA GRAS list?

It is. FEMA number 4412 covers cis-3-Nonen-1-ol. It is also codified at 21 CFR 172.515.

What is the FEMA number for cis-3-Nonen-1-ol?

The FEMA number for cis-3-Nonen-1-ol is 4412 and its CAS registry number is 10340-23-5. FEMA files it in the fruity flavor category.

Is cis-3-Nonen-1-ol natural or artificial?

Since cis-3-Nonen-1-ol is found in nature, US labeling follows how it was obtained: natural flavor from a natural source and a natural process, artificial when cis-3-Nonen-1-ol is synthesized. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic cis-3-Nonen-1-ol identical-to-natural.

Is cis-3-Nonen-1-ol approved in the EU?

cis-3-Nonen-1-ol is on the EU Union List of flavouring substances as FL 02.234 (Annex I Part A) under Regulation 1334/2008.

Has JECFA evaluated cis-3-Nonen-1-ol?

Yes. JECFA number 2177, evaluated at the 76th meeting in 2012. Conclusion: No safety concern at current levels of intake when used as a flavouring agent.

What is cis-3-Nonen-1-ol used for?

cis-3-Nonen-1-ol is described as sweet, fruity, green, floral, herbaceous. It shows up in beverage, confection, fruit flavors, bakery and dairy.

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as CIS-3-NONEN-1-OL under CAS 10340-23-5 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.