Flavor ingredient regulatory record

Furfuryl methyl sulfide

Furfuryl methyl sulfide is a thiol in the sulfur family, FEMA GRAS under FEMA number 3160 (CAS 1438-91-1). Its odor is earthy, roasted, nutty, savory.

FEMA
3160
CAS
1438-91-1
JECFA
1076
EU FL
13.053
Formula
C6H8OS
EC
215-874-0

GRAS status: FEMA GRAS, publication 4. Recorded by FDA in the Substances Added to Food inventory under CAS 1438-91-1.

Structure

2D structure of Furfuryl methyl sulfide
Structure of Furfuryl methyl sulfide, C6H8OS. Drawn from the canonical SMILES.

Identity

IUPAC name 2-(methylsulfanylmethyl)furan
CAS number 1438-91-1
FEMA number 3160
Molecular formula C6H8OS
Molecular weight 128.2 g/mol
SMILES CSCc1ccco1
InChIKey SKSFHXVDHVKIBN-UHFFFAOYSA-N
PubChem CID 518937
EC number 215-874-0
FDA UNII LMB8355W32
EPA DTXSID DTXSID7061693
Chemical class Thiol
Boiling point 65 °C
Flash point 15 °C

Also known as: Furan, 2-[(methylthio)methyl]-, 2-[(Methylthio)methyl]furan, Methyl furfuryl sulfide, 2-(Methylthiomethyl)furan, 2-Furfuryl methyl sulfide, 2-(Methylsulfanylmethyl)furan, 2-[(Methylsulfanyl)methyl]furan, 2-((methylthio)methyl)furan, methyl furfuryl sulfide, 2-furfuryl methyl sulfide, furan, 2-[(methylthio)methyl]-, 2-[(methylthio)methyl]furan.

Can Furfuryl methyl sulfide be labeled natural?

Furfuryl methyl sulfide occurs in nature, so the label depends on the route: furfuryl methyl sulfide won from a natural source by a physical, enzymatic or microbiological process is natural flavor in the United States, and synthesized furfuryl methyl sulfide is artificial. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.

United States
Natural or artificial, by process
European Union and UK
Natural only from natural material
Mercosur and Mexico
Natural or identical-to-natural

How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.

Regulatory status, with citations

United States

Furfuryl methyl sulfide is FEMA GRAS under FEMA number 3160. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 13.053, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.

JECFA (WHO / FAO)

JECFA number 1076, evaluated at the 59th meeting in 2002. No safety concern at current levels of intake when used as a flavouring agent.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

TSCA Inventory status

A flavor ingredient is also an industrial chemical. Furfuryl methyl sulfide appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 1438-91-1, where EPA names it Furan, 2-[(methylthio)methyl]-.

Active in US commerce

EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.

EPA publishes no regulatory flags on this listing. What the flags mean.

From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.

Odor and taste

Odor: Earthy, roasted, nutty, savory.

Where it is used

Furfuryl methyl sulfide is used in savory dishes, seasoning blends, snack foods and sauces, typically as a sulfur note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to Furfuryl methyl sulfide by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
2-Methyl-5-(methylthio)furan336685%In nature
Furfuryl methyl ether315985%In nature
S-Methyl thiofuroate331182%In nature

More thiols in this index

(+/-)-2-Mercaptomethylpentan-1-ol · Furfuryl isopropyl sulfide · S-Methyl benzothioate · 2-Methyltetrahydrothiophen-3-one · 3-(Methylthio)propylamine · 3,4-Dimethylthiophene

Furfuryl methyl sulfide FAQ

Does furfuryl methyl sulfide have FEMA GRAS status?

Furfuryl methyl sulfide holds FEMA GRAS status under FEMA number 3160. It is also codified at 21 CFR 172.515.

How do I cite furfuryl methyl sulfide by FEMA or CAS number?

Cite furfuryl methyl sulfide as FEMA 3160 or CAS 1438-91-1; both point to the same entry. FEMA files it in the sulfur flavor category.

Can furfuryl methyl sulfide be labeled a natural flavor?

Since furfuryl methyl sulfide is found in nature, US labeling follows how it was obtained: natural flavor from a natural source and a natural process, artificial when furfuryl methyl sulfide is synthesized. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.

Can furfuryl methyl sulfide be used in the EU and UK?

Furfuryl methyl sulfide is on the EU Union List of flavouring substances as FL 13.053 (Annex I Part A) under Regulation 1334/2008.

Has JECFA evaluated furfuryl methyl sulfide?

Yes. JECFA number 1076, evaluated at the 59th meeting in 2002. Conclusion: No safety concern at current levels of intake when used as a flavouring agent.

What does furfuryl methyl sulfide smell and taste like, and where is it used?

The odor of furfuryl methyl sulfide is earthy, roasted, nutty, savory. Typical uses are savory dishes, seasoning blends, snack foods and sauces.

Ingredient lookup

Check an ingredient

Start typing to search the ingredient corpus.

Or browse every ingredient page, A to Z.

Guides: What Is FEMA GRAS? · Natural vs artificial · Filing a GRAS notification

Check Furfuryl methyl sulfide in a formula

Screened against FEMA GRAS, 21 CFR and EU rules as you build. Free to start.

Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as FURFURYL METHYL SULFIDE under CAS 1438-91-1 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.