Flavor ingredient regulatory record
Linalool oxide pyranoid
Linalool oxide pyranoid is a terpene in the floral family, FEMA GRAS under FEMA number 4593 (CAS 14049-11-7). Its odor is floral, sweet, herbal, citrus.
- FEMA
- 4593
- CAS
- 14049-11-7
- JECFA
- 2135
- Formula
- C10H18O2
GRAS status: FEMA GRAS, publication 24. Recorded by FDA in the Substances Added to Food inventory under CAS 14049-11-7.
Structure
Identity
Also known as: 2H-Pyran-3-ol, 6-ethenyltetrahydro-2,2,6-trimethyl-, 2H-Pyran-3-ol, tetrahydro-2,2,6-trimethyl-6-vinyl-, Pyran-3-ol, tetrahydro-2,2,6-trimethyl-6-vinyl-, 6-Ethenyltetrahydro-2,2,6-trimethyl-2H-pyran-3-ol, Epoxylinalool, 2,6,6-Trimethyl-2-vinyl-5-hydroxytetrahydropyran, 2,2,6-Trimethyl-6-vinyltetrahydro-2H-pyran-3-ol, Linalool oxide, 2,2-Dimethyl-3-hydroxy-6-methyl-6-vinyltetrahydropyran, 2,2,6-Trimethyl-6-ethenyltetrahydro-2H-pyran-3-ol, Tetrahydro-2,2,6-trimethyl-6-vinyl-2H-pyran-3-ol, 3-Hydroxy-2,2,6-trimethyl-6-vinyltetrahydropyran.
Can Linalool oxide pyranoid be labeled natural?
Nature makes linalool oxide pyranoid, which is why the US label turns on process. A natural route gives natural flavor; synthesis gives artificial linalool oxide pyranoid, same molecule. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic linalool oxide pyranoid identical-to-natural.
- United States
- Natural or artificial, by process
- European Union and UK
- Natural only from natural material
- Mercosur and Mexico
- Natural or identical-to-natural
How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.
Regulatory status, with citations
United States
Linalool oxide pyranoid is FEMA GRAS under FEMA number 4593. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
No EU FL number is on file for Linalool oxide pyranoid. That is not a finding either way. The Union List covers defined flavouring substances, so natural complex materials are handled as flavouring preparations under Parts B to F and never receive a number, and substances used as additives sit under Regulation 1333/2008 instead. Confirm the position before EU or UK use.
JECFA (WHO / FAO)
JECFA number 2135, evaluated at the 76th meeting in 2012. no safety concern at current levels of intake.
Other US flags
Not on the California Proposition 65 list. Listed on the EPA TSCA inventory.
TSCA Inventory status
A flavor ingredient is also an industrial chemical. Linalool oxide pyranoid appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 14049-11-7, where EPA names it 2H-Pyran-3-ol, 6-ethenyltetrahydro-2,2,6-trimethyl-.
Active in US commerce
EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.
EPA publishes no regulatory flags on this listing. What the flags mean.
From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.
Odor and taste
Odor: Floral, sweet, herbal, citrus.
Where it is used
Linalool oxide pyranoid is used in beverage, fragrance, confection and cosmetics, typically as a floral note.
Structurally similar flavor ingredients
Flavor ingredients with a GRAS determination closest to Linalool oxide pyranoid by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.
| Material | FEMA | Similarity | Occurrence |
|---|---|---|---|
| 2,2,6-Trimethyl-6-vinyltetrahydropyran | 3735 | 82% | In nature |
| (+/-)-2-(5-Methyl-5-vinyl-tetrahydrofuran-2-yl)propionaldehyde | 4058 | 70% | In nature |
| 8-p-Menthene-1,2-diol | 4409 | 67% | In nature |
| Dihydrocarveol | 2379 | 60% | In nature |
| p-Menth-8-en-1-ol | 3564 | 57% | In nature |
More terpenes in this index
beta-Bisabolene · Farnesol · Nerolidol oxide · alpha-Ionol · Nerol oxide · (+/-)-Dihydrofarnesol
Linalool oxide pyranoid FAQ
Is linalool oxide pyranoid FEMA GRAS?
Yes. The FEMA Expert Panel lists linalool oxide pyranoid as GRAS under FEMA number 4593. The Code of Federal Regulations lists it at 21 CFR 172.515.
What are the FEMA and CAS numbers for linalool oxide pyranoid?
Linalool oxide pyranoid is FEMA 4593, CAS 14049-11-7. Its flavor category is floral.
How is linalool oxide pyranoid described, and where does it show up?
Flavorists describe linalool oxide pyranoid as floral, sweet, herbal, citrus. It is used in beverage, fragrance, confection and cosmetics.
What did JECFA conclude about linalool oxide pyranoid?
JECFA evaluated linalool oxide pyranoid at the 76th meeting in 2012 under JECFA number 2135. The panel concluded: no safety concern at current levels of intake.
Is linalool oxide pyranoid approved in the EU?
No EU FL number is on file for linalool oxide pyranoid. It has a JECFA evaluation (JECFA 2135), which the EU list draws on, but the Union List entry itself should be confirmed before EU use.
Does linalool oxide pyranoid count as natural in the US and the EU?
The process decides for linalool oxide pyranoid. It occurs in nature, so a natural-source, natural-process material is natural flavor in the US and synthetic linalool oxide pyranoid is artificial. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic linalool oxide pyranoid identical-to-natural.
Ingredient lookup
Check an ingredient
Start typing to search the ingredient corpus.
Or browse every ingredient page, A to Z.
Guides: What Is FEMA GRAS? · Natural vs artificial · Filing a GRAS notification
Check Linalool oxide pyranoid in a formula
Screened against FEMA GRAS, 21 CFR and EU rules as you build. Free to start.
Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as LINALOOL OXIDE PYRANOID under CAS 14049-11-7 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.