Flavor ingredient regulatory record
8-p-Menthene-1,2-diol
8-p-Menthene-1,2-diol is an alcohol in the mint family, FEMA GRAS under FEMA number 4409 (CAS 1946-00-5). Its odor is fresh, minty, herbal, cool.
- FEMA
- 4409
- CAS
- 1946-00-5
- JECFA
- 1860
- Formula
- C10H18O2
GRAS status: FEMA GRAS, publication 23. Recorded by FDA in the Substances Added to Food inventory under CAS 1946-00-5.
Structure
Identity
Also known as: 1,2-Cyclohexanediol, 1-methyl-4-(1-methylethenyl)-, p-Menth-8-ene-1,2-diol, 1-Methyl-4-(1-methylethenyl)-1,2-cyclohexanediol, 8,9-p-Menthen-1,2-diol, d-Limonene-1,2-diol, Limonene glycol, Limonene-1,2-diol, 4-(1-Methylethenyl)-1-methylcyclohexane-1,2-diol, 1-Methyl-4-(prop-1-en-2-yl)cyclohexane-1,2-diol, 1,2-cyclohexanediol, 1-methyl-4-(1-methylethenyl)-, limonene-1,2-diol, 1-methyl-4-(prop-1-en-2-yl)cyclohexane-1,2-diol.
Can 8-p-Menthene-1,2-diol be labeled natural?
Nature makes 8-p-Menthene-1,2-diol, which is why the US label turns on process. A natural route gives natural flavor; synthesis gives artificial 8-p-Menthene-1,2-diol, same molecule. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.
- United States
- Natural or artificial, by process
- European Union and UK
- Natural only from natural material
- Mercosur and Mexico
- Natural or identical-to-natural
How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.
Regulatory status, with citations
United States
8-p-Menthene-1,2-diol is FEMA GRAS under FEMA number 4409. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
No EU FL number is on file for 8-p-Menthene-1,2-diol. That is not a finding either way. The Union List covers defined flavouring substances, so natural complex materials are handled as flavouring preparations under Parts B to F and never receive a number, and substances used as additives sit under Regulation 1333/2008 instead. Confirm the position before EU or UK use.
JECFA (WHO / FAO)
JECFA number 1860, evaluated at the 69th meeting in 2008. no safety concern at current levels of intake.
Other US flags
Not on the California Proposition 65 list.
TSCA Inventory status
A flavor ingredient is also an industrial chemical. 8-p-Menthene-1,2-diol appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 1946-00-5, where EPA names it 1,2-Cyclohexanediol, 1-methyl-4-(1-methylethenyl)-.
Inactive in US commerce
EPA designates this substance inactive, so a Notice of Activity Form B is required before anyone manufactures or processes it again. Being FEMA GRAS does not change that. What active and inactive mean.
EPA publishes no regulatory flags on this listing. What the flags mean.
From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.
Odor and taste
Odor: Fresh, minty, herbal, cool.
Where it is used
8-p-Menthene-1,2-diol is used in beverage, confection, oral care and flavoring, typically as a mint note.
Structurally similar flavor ingredients
Flavor ingredients with a GRAS determination closest to 8-p-Menthene-1,2-diol by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.
| Material | FEMA | Similarity | Occurrence |
|---|---|---|---|
| Dihydrocarveol | 2379 | 89% | In nature |
| p-Menth-8-en-1-ol | 3564 | 88% | In nature |
| Carveol | 2247 | 88% | In nature |
| Linalool | 2635 | 73% | In nature |
| p-Menth-3-en-1-ol | 3563 | 72% | In nature |
More alcohols in this index
2-(l-Menthoxy)ethanol · p-Menth-8-en-1-ol · D,L-Menthol(+/-)-propylene glycol carbonate · (-)-Menthol 1- and 2-propylene glycol carbonate · p-Menthane-3,8-diol · 2,4-Nonadien-1-ol
8-p-Menthene-1,2-diol FAQ
Is 8-p-Menthene-1,2-diol on the FEMA GRAS list?
It is. FEMA number 4409 covers 8-p-Menthene-1,2-diol. The Code of Federal Regulations lists it at 21 CFR 172.515.
What is the FEMA number for 8-p-Menthene-1,2-diol?
The FEMA number for 8-p-Menthene-1,2-diol is 4409 and its CAS registry number is 1946-00-5. Its flavor category is mint.
What is 8-p-Menthene-1,2-diol used for?
8-p-Menthene-1,2-diol is described as fresh, minty, herbal, cool. It shows up in beverage, confection, oral care and flavoring.
What did JECFA conclude about 8-p-Menthene-1,2-diol?
JECFA evaluated 8-p-Menthene-1,2-diol at the 69th meeting in 2008 under JECFA number 1860. The panel concluded: no safety concern at current levels of intake.
Is 8-p-Menthene-1,2-diol approved in the EU?
No EU FL number is on file for 8-p-Menthene-1,2-diol. It has a JECFA evaluation (JECFA 1860), which the EU list draws on, but the Union List entry itself should be confirmed before EU use.
Is 8-p-Menthene-1,2-diol natural or artificial?
The process decides for 8-p-Menthene-1,2-diol. It occurs in nature, so a natural-source, natural-process material is natural flavor in the US and synthetic 8-p-Menthene-1,2-diol is artificial. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.
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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as 8-P-MENTHENE-1,2-DIOL under CAS 1946-00-5 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.