Flavor ingredient regulatory record
2-Ethyl-1-hexanol
2-Ethyl-1-hexanol is an alcohol in the fruity family, FEMA GRAS under FEMA number 3151 (CAS 104-76-7). Its odor is sweet, fruity, floral, green, slightly fatty.
- FEMA
- 3151
- CAS
- 104-76-7
- JECFA
- 267
- EU FL
- 02.082
- Formula
- C8H18O
- EC
- 203-234-3
GRAS status: FEMA GRAS, publication 4. Recorded by FDA in the Substances Added to Food inventory under CAS 104-76-7.
Structure
Identity
Also known as: 1-Hexanol, 2-ethyl-, 2-Ethylhexanol, 2-Ethylhexyl alcohol, Ethylhexanol, (±)-2-Ethyl-1-hexanol, 2-Ethyl-1-hexyl alcohol, NSC 9300, G 301, Guerbet C8, 2-ethylhexan-1-ol, 2-ethylhexanol, 2-ethylhexyl alcohol.
Can 2-Ethyl-1-hexanol be labeled natural?
The process decides for 2-Ethyl-1-hexanol. It occurs in nature, so a natural-source, natural-process material is natural flavor in the US and synthetic 2-Ethyl-1-hexanol is artificial. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.
- United States
- Natural or artificial, by process
- European Union and UK
- Natural only from natural material
- Mercosur and Mexico
- Natural or identical-to-natural
How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.
Regulatory status, with citations
United States
2-Ethyl-1-hexanol is FEMA GRAS under FEMA number 3151. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
Listed on the Union List of flavouring substances as FL 02.082, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (JECFA). The UK retains the same list.
JECFA (WHO / FAO)
JECFA number 267, evaluated at the 49th meeting in 1997. no safety concern at current levels of intake.
Other US flags
Not on the California Proposition 65 list.
TSCA Inventory status
A flavor ingredient is also an industrial chemical. 2-Ethyl-1-hexanol appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 104-76-7, where EPA names it 1-Hexanol, 2-ethyl-.
Active in US commerce
EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.
EPA publishes no regulatory flags on this listing. What the flags mean.
From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.
Odor and taste
Odor: Sweet, fruity, floral, green, slightly fatty.
Where it is used
2-Ethyl-1-hexanol is used in beverage, confection, fruit flavors and flavoring agents, typically as a fruity note.
Structurally similar flavor ingredients
Flavor ingredients with a GRAS determination closest to 2-Ethyl-1-hexanol by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.
| Material | FEMA | Similarity | Occurrence |
|---|---|---|---|
| 3-Heptanol | 3547 | 95% | In nature |
| Heptan-2-ol | 3288 | 93% | In nature |
| Hexyl alcohol | 2567 | 92% | In nature |
| 3-Octanol | 3581 | 86% | In nature |
| 1-Octanol | 2800 | 81% | In nature |
More alcohols in this index
2-Octen-1-ol · cis-5-Octen-1-ol · 3-Heptanol · (E)- and (Z)-2,4,8-Trimethyl-3,7-nonadien-2-ol · 3-Phenyl-1-propanol · (Z)-4-Hepten-1-ol
2-Ethyl-1-hexanol FAQ
Does 2-Ethyl-1-hexanol have FEMA GRAS status?
2-Ethyl-1-hexanol holds FEMA GRAS status under FEMA number 3151. The Code of Federal Regulations lists it at 21 CFR 172.515.
How do I cite 2-Ethyl-1-hexanol by FEMA or CAS number?
Cite 2-Ethyl-1-hexanol as FEMA 3151 or CAS 104-76-7; both point to the same entry. Its flavor category is fruity.
What does 2-Ethyl-1-hexanol smell and taste like, and where is it used?
The odor of 2-Ethyl-1-hexanol is sweet, fruity, floral, green, slightly fatty. Typical uses are beverage, confection, fruit flavors and flavoring agents.
What did JECFA conclude about 2-Ethyl-1-hexanol?
JECFA evaluated 2-Ethyl-1-hexanol at the 49th meeting in 1997 under JECFA number 267. The panel concluded: no safety concern at current levels of intake.
Can 2-Ethyl-1-hexanol be used in the EU and UK?
Yes. FL 02.082 is the Union List entry for 2-Ethyl-1-hexanol, annex I Part A, under Regulation 1334/2008, and the UK keeps the same list.
Can 2-Ethyl-1-hexanol be labeled a natural flavor?
Nature makes 2-Ethyl-1-hexanol, which is why the US label turns on process. A natural route gives natural flavor; synthesis gives artificial 2-Ethyl-1-hexanol, same molecule. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic 2-Ethyl-1-hexanol identical-to-natural.
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Guides: What Is FEMA GRAS? · Natural vs artificial · Filing a GRAS notification
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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as 2-ETHYL-1-HEXANOL under CAS 104-76-7 and carries its FEMA number, its JECFA flavor number and its 21 CFR citations. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.