Flavor ingredient regulatory record
Hexyl alcohol
Hexyl alcohol is an alcohol in the green family, FEMA GRAS under FEMA number 2567 (CAS 111-27-3). Its odor is green, grassy, herbaceous, woody.
- FEMA
- 2567
- CAS
- 111-27-3
- JECFA
- 91
- EU FL
- 02.005
- Formula
- C6H14O
- EC
- 203-852-3
GRAS status: FEMA GRAS, publication 3. Recorded by FDA in the Substances Added to Food inventory under CAS 111-27-3.
Structure
Identity
Also known as: 1-Hexanol, Amylcarbinol, Caproyl alcohol, n-Hexanol, 1-Hydroxyhexane, n-Hexyl alcohol, Pentylcarbinol, 1-Hexyl alcohol, Hexanol, n-Hexan-1-ol, Epal 6, NSC 9254.
Can Hexyl alcohol be labeled natural?
The process decides for hexyl alcohol. It occurs in nature, so a natural-source, natural-process material is natural flavor in the US and synthetic hexyl alcohol is artificial. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic hexyl alcohol identical-to-natural.
- United States
- Natural or artificial, by process
- European Union and UK
- Natural only from natural material
- Mercosur and Mexico
- Natural or identical-to-natural
How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.
Regulatory status, with citations
United States
Hexyl alcohol is FEMA GRAS under FEMA number 2567. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
Listed on the Union List of flavouring substances as FL 02.005, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (JECFA). The UK retains the same list.
JECFA (WHO / FAO)
JECFA number 91, evaluated at the 49th meeting in 1997. No safety concern at current levels of intake when used as a flavouring agent.
Other US flags
Not on the California Proposition 65 list.
TSCA Inventory status
A flavor ingredient is also an industrial chemical. Hexyl alcohol appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 111-27-3, where EPA names it 1-Hexanol.
Active in US commerce
EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.
EPA publishes no regulatory flags on this listing. What the flags mean.
From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.
Odor and taste
Odor: Green, grassy, herbaceous, woody.
Taste: Green, slightly sweet.
Where it is used
Hexyl alcohol is used in green, herbal and woody, typically as a green note.
Structurally similar flavor ingredients
Flavor ingredients with a GRAS determination closest to Hexyl alcohol by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.
| Material | FEMA | Similarity | Occurrence |
|---|---|---|---|
| cis-3-Hexen-1-ol | 2563 | 95% | In nature |
| trans-3-Hexenol | 4356 | 95% | In nature |
| Heptan-2-ol | 3288 | 94% | In nature |
| 4-Hexen-1-ol | 3430 | 94% | In nature |
| 2-Hexen-1-ol | 2562 | 94% | In nature |
More alcohols in this index
trans-3-Hexenol · cis-3-Hexen-1-ol · alpha-Amylcinnamyl alcohol · (E,E)-2,4-Decadien-1-ol · Heptan-2-ol · cis-3-Octen-1-ol
Hexyl alcohol FAQ
Is hexyl alcohol on the FEMA GRAS list?
It is. FEMA number 2567 covers hexyl alcohol. The Code of Federal Regulations lists it at 21 CFR 172.515.
What is the FEMA number for hexyl alcohol?
The FEMA number for hexyl alcohol is 2567 and its CAS registry number is 111-27-3. Its flavor category is green.
What is hexyl alcohol used for?
Hexyl alcohol is described as green, grassy, herbaceous, woody. On the palate it is green, slightly sweet. It shows up in green, herbal and woody.
What did JECFA conclude about hexyl alcohol?
JECFA evaluated hexyl alcohol at the 49th meeting in 1997 under JECFA number 91. The panel concluded: No safety concern at current levels of intake when used as a flavouring agent.
Is hexyl alcohol approved in the EU?
Yes. FL 02.005 is the Union List entry for hexyl alcohol, annex I Part A, under Regulation 1334/2008, and the UK keeps the same list.
Is hexyl alcohol natural or artificial?
Nature makes hexyl alcohol, which is why the US label turns on process. A natural route gives natural flavor; synthesis gives artificial hexyl alcohol, same molecule. The EU and UK grant the natural claim only to that natural route; Mercosur and Mexico call synthetic material identical-to-natural.
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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as HEXYL ALCOHOL under CAS 111-27-3 and carries its FEMA number, its JECFA flavor number and its 21 CFR citations. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.