Flavor ingredient regulatory record
Methyl myristate
Methyl myristate is an ester in the fruity family, FEMA GRAS under FEMA number 2722 (CAS 124-10-7). Its odor is sweet, fruity, creamy, tropical, estery.
- FEMA
- 2722
- CAS
- 124-10-7
- JECFA
- 183
- EU FL
- 09.106
- Formula
- C15H30O2
- EC
- 204-680-1
GRAS status: FEMA GRAS, publication 3. Recorded by FDA in the Substances Added to Food inventory under CAS 124-10-7.
Structure
Identity
Also known as: Tetradecanoic acid, methyl ester, Myristic acid, methyl ester, Metholeneat 2495, Methyl tetradecanoate, Uniphat A50, Methyl n-tetradecanoate, Pastell M 14, NSC 5029, Emery 2214, methyl tetradecanoate, tetradecanoic acid, methyl ester, uniphat a50.
Can Methyl myristate be labeled natural?
Since methyl myristate is found in nature, US labeling follows how it was obtained: natural flavor from a natural source and a natural process, artificial when methyl myristate is synthesized. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic methyl myristate identical-to-natural.
- United States
- Natural or artificial, by process
- European Union and UK
- Natural only from natural material
- Mercosur and Mexico
- Natural or identical-to-natural
How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.
Regulatory status, with citations
United States
Methyl myristate is FEMA GRAS under FEMA number 2722. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
Listed on the Union List of flavouring substances as FL 09.106, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (JECFA). The UK retains the same list.
JECFA (WHO / FAO)
JECFA number 183, evaluated at the 49th meeting in 1997. No safety concern at current levels of intake when used as a flavouring agent.
Other US flags
Not on the California Proposition 65 list.
TSCA Inventory status
A flavor ingredient is also an industrial chemical. Methyl myristate appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 124-10-7, where EPA names it Tetradecanoic acid, methyl ester.
Active in US commerce
EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.
EPA publishes no regulatory flags on this listing. What the flags mean.
From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.
Odor and taste
Odor: Sweet, fruity, creamy, tropical, estery.
Where it is used
Methyl myristate is used in beverage, confection, dairy, fruit flavors and bakery, typically as a fruity note.
Structurally similar flavor ingredients
Flavor ingredients with a GRAS determination closest to Methyl myristate by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.
| Material | FEMA | Similarity | Occurrence |
|---|---|---|---|
| Ethyl hexadecanoate | 2451 | 98% | In nature |
| Lauryl acetate | 2616 | 98% | In nature |
| Dodecyl butyrate | 4340 | 98% | In nature |
| Butyl laurate | 2206 | 98% | In nature |
| Octyl octanoate | 2811 | 97% | In nature |
More esters in this index
alpha-Methylphenethyl butyrate · trans-3-Hexenyl formate · Isobutyl 3-(2-furan)propionate · Dodecyl butyrate · Allyl cinnamate · Guaiacol butyrate
Methyl myristate FAQ
Does methyl myristate have FEMA GRAS status?
Methyl myristate holds FEMA GRAS status under FEMA number 2722. It is also codified at 21 CFR 172.515.
How do I cite methyl myristate by FEMA or CAS number?
Cite methyl myristate as FEMA 2722 or CAS 124-10-7; both point to the same entry. FEMA files it in the fruity flavor category.
Can methyl myristate be labeled a natural flavor?
Methyl myristate occurs in nature, so the label depends on the route: methyl myristate won from a natural source by a physical, enzymatic or microbiological process is natural flavor in the United States, and synthesized methyl myristate is artificial. The EU and UK grant the natural claim only to that natural route; Mercosur and Mexico call synthetic material identical-to-natural.
Can methyl myristate be used in the EU and UK?
Methyl myristate is on the EU Union List of flavouring substances as FL 09.106 (Annex I Part A) under Regulation 1334/2008.
Has JECFA evaluated methyl myristate?
Yes. JECFA number 183, evaluated at the 49th meeting in 1997. Conclusion: No safety concern at current levels of intake when used as a flavouring agent.
What does methyl myristate smell and taste like, and where is it used?
The odor of methyl myristate is sweet, fruity, creamy, tropical, estery. Typical uses are beverage, confection, dairy, fruit flavors and bakery.
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Guides: What Is FEMA GRAS? · Natural vs artificial · Filing a GRAS notification
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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as METHYL MYRISTATE under CAS 124-10-7 and carries its FEMA number, its JECFA flavor number and its 21 CFR citations. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.