Flavor ingredient regulatory record

N-Lactoyl ethanolamine phosphate

N-Lactoyl ethanolamine phosphate is a phosphate in the dairy family, FEMA GRAS under FEMA number 4257 (CAS 782498-03-7). Its odor is creamy, milky, slightly sweet, nutty.

FEMA
4257
CAS
782498-03-7
JECFA
1775
EU FL
16.104
Formula
C5H12NO6P

GRAS status: FEMA GRAS, publication 23. Recorded by FDA in the Substances Added to Food inventory under CAS 782498-03-7.

Structure

2D structure of N-Lactoyl ethanolamine phosphate
Structure of N-Lactoyl ethanolamine phosphate, C5H12NO6P. Drawn from the canonical SMILES.

Identity

IUPAC name 2-(2-hydroxypropanoylamino)ethyl dihydrogen phosphate
CAS number 782498-03-7
FEMA number 4257
Molecular formula C5H12NO6P
Molecular weight 213.13 g/mol
SMILES CC(O)C(=O)NCCOP(=O)(O)O
InChIKey CKXSSEHWXMVQRZ-UHFFFAOYSA-N
PubChem CID 11550267
FDA UNII 1NR0E369CN
EPA DTXSID DTXSID50999596
Chemical class Phosphate

Also known as: Propanamide, 2-hydroxy-N-[2-(phosphonooxy)ethyl]-, 2-Hydroxy-N-[2-(phosphonooxy)ethyl]propanamide, n-lactoyl ethanolamine phosphate [fhfi], 2-hydroxy-n-(2-(phosphonooxy)ethyl)propanamide, propanamide, 2-hydroxy-n-(2-(phosphonooxy)ethyl)-, lactoyl monoethanolamide phosphate, [2-(2-hydroxypropanamido)ethoxy]phosphonic acid, (2-(2-hydroxypropanamido)ethoxy)phosphonic acid, 2-hydroxy-n-[2-(phosphonooxy)ethyl]propanamide, (+-)-n-lactoyl ethanolamine phosphate, n-lactoyl ethanolamine phosphate, (+-)-, (+/-)-n-lactoyl ethanolamine phosphate.

Can N-Lactoyl ethanolamine phosphate be labeled natural?

Nature occurrence: Not yet found in nature (provisional).

Nature occurrence has not been settled for this substance, so the natural or artificial class is not stated here. The FEMA GRAS status does not depend on it.

Regulatory status, with citations

United States

N-Lactoyl ethanolamine phosphate is FEMA GRAS under FEMA number 4257. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 16.104, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.

JECFA (WHO / FAO)

JECFA number 1775, evaluated at the 68th meeting in 2007. No safety concern at current levels of intake when used as a flavouring agent.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

Odor and taste

Odor: Creamy, milky, slightly sweet, nutty.

Taste: Savory, creamy, umami.

Where it is used

N-Lactoyl ethanolamine phosphate is used in dairy, cheese, sauces and snacks, typically as a dairy note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to N-Lactoyl ethanolamine phosphate by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
Phosphoric Acid290056%In nature
L-Alanyl-L-Glutamine471247%Not determined
Glutamyl-valyl-glycine470944%Not determined
N-(2-Hydroxyethyl)galactonamide425443%In nature
4-Hydroxy-3-methoxycinnamic acid381242%In nature

N-Lactoyl ethanolamine phosphate FAQ

Is N-Lactoyl ethanolamine phosphate FEMA GRAS?

Yes. The FEMA Expert Panel lists N-Lactoyl ethanolamine phosphate as GRAS under FEMA number 4257. The Code of Federal Regulations lists it at 21 CFR 172.515.

What are the FEMA and CAS numbers for N-Lactoyl ethanolamine phosphate?

N-Lactoyl ethanolamine phosphate is FEMA 4257, CAS 782498-03-7. Its flavor category is dairy.

How is N-Lactoyl ethanolamine phosphate described, and where does it show up?

Flavorists describe N-Lactoyl ethanolamine phosphate as creamy, milky, slightly sweet, nutty. On the palate it is savory, creamy, umami. It is used in dairy, cheese, sauces and snacks.

What did JECFA conclude about N-Lactoyl ethanolamine phosphate?

JECFA evaluated N-Lactoyl ethanolamine phosphate at the 68th meeting in 2007 under JECFA number 1775. The panel concluded: No safety concern at current levels of intake when used as a flavouring agent.

Is N-Lactoyl ethanolamine phosphate on the EU Union List?

Yes. FL 16.104 is the Union List entry for N-Lactoyl ethanolamine phosphate, annex I Part A, under Regulation 1334/2008, and the UK keeps the same list.

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as N-LACTOYL ETHANOLAMINE PHOSPHATE under CAS 782498-03-7 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.