Flavor ingredient regulatory record
Nerolidol oxide
Nerolidol oxide is a terpene in the floral family, FEMA GRAS under FEMA number 4536 (CAS 1424-83-5). Its odor is floral, sweet, herbal, green.
- FEMA
- 4536
- CAS
- 1424-83-5
- JECFA
- 2137
GRAS status: FEMA GRAS, publication 24. Recorded by FDA in the Substances Added to Food inventory under CAS 1424-83-5.
Structure
Under review
The structure for Nerolidol oxide is still under identity review, so no drawing is shown until the record is confirmed.
Identity
Also known as: 6,10-dimethyl-2-(oxiran-2-yl)undeca-5,9-dien-2-ol.
Can Nerolidol oxide be labeled natural?
Nature occurrence: Not yet found in nature (provisional).
Nature occurrence has not been settled for this substance, so the natural or artificial class is not stated here. The FEMA GRAS status does not depend on it.
Regulatory status, with citations
United States
Nerolidol oxide is FEMA GRAS under FEMA number 4536. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
No EU FL number is on file for Nerolidol oxide. That is not a finding either way. The Union List covers defined flavouring substances, so natural complex materials are handled as flavouring preparations under Parts B to F and never receive a number, and substances used as additives sit under Regulation 1333/2008 instead. Confirm the position before EU or UK use.
JECFA (WHO / FAO)
JECFA number 2137.
Other US flags
Not on the California Proposition 65 list. Listed on the EPA TSCA inventory.
Odor and taste
Odor: Floral, sweet, herbal, green.
Where it is used
Nerolidol oxide is used in beverage, fragrance, confection and cosmetics, typically as a floral note.
Structurally similar flavor ingredients
Flavor ingredients with a GRAS determination closest to Nerolidol oxide by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.
| Material | FEMA | Similarity | Occurrence |
|---|---|---|---|
| N-3,7-Dimethyl-2,6-octadienyl cyclopropylcarboxamide | 4267 | 72% | In nature |
More terpenes in this index
(+/-)-Dihydrofarnesol · beta-Ionol · alpha -Bisabolene · alpha-Ionol · beta-Bisabolene · alpha-bisabolol
Nerolidol oxide FAQ
Is nerolidol oxide FEMA GRAS?
Yes. The FEMA Expert Panel lists nerolidol oxide as GRAS under FEMA number 4536. It is also codified at 21 CFR 172.515.
What are the FEMA and CAS numbers for nerolidol oxide?
Nerolidol oxide is FEMA 4536, CAS 1424-83-5. FEMA files it in the floral flavor category.
Is nerolidol oxide approved in the EU?
No EU FL number is on file for nerolidol oxide. It has a JECFA evaluation (JECFA 2137), which the EU list draws on, but the Union List entry itself should be confirmed before EU use.
Has JECFA evaluated nerolidol oxide?
Yes. JECFA number 2137.
How is nerolidol oxide described, and where does it show up?
Flavorists describe nerolidol oxide as floral, sweet, herbal, green. It is used in beverage, fragrance, confection and cosmetics.
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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as NEROLIDOL OXIDE under CAS 1424-83-5 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.