Flavor ingredient regulatory record

N-3,7-Dimethyl-2,6-octadienyl cyclopropylcarboxamide

N-3,7-Dimethyl-2,6-octadienyl cyclopropylcarboxamide is an amide in the fruity family, FEMA GRAS under FEMA number 4267 (CAS 744251-93-2). Its odor is herbaceous, green, slightly sweet, earthy.

FEMA
4267
CAS
744251-93-2
JECFA
1779
EU FL
16.095
Formula
C14H23NO

GRAS status: FEMA GRAS, publication 23. Recorded by FDA in the Substances Added to Food inventory under CAS 744251-93-2.

Structure

2D structure of N-3,7-Dimethyl-2,6-octadienyl cyclopropylcarboxamide
Structure of N-3,7-Dimethyl-2,6-octadienyl cyclopropylcarboxamide, C14H23NO. Drawn from the canonical SMILES.

Identity

IUPAC name N-[(2E)-3,7-dimethylocta-2,6-dienyl]cyclopropanecarboxamide
CAS number 744251-93-2
FEMA number 4267
Molecular formula C14H23NO
Molecular weight 221.34 g/mol
SMILES CC(C)=CCC/C(C)=C/CNC(=O)C1CC1
InChIKey UKNMSFRSBQONET-FMIVXFBMSA-N
PubChem CID 11658617
FDA UNII 0T7H9YA5WZ
EPA DTXSID DTXSID70225440
Chemical class Amide
Flash point 161 °C

Also known as: Cyclopropanecarboxamide, N-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-, Cyclopropanecarboxamide, N-[(2E)-3,7-dimethyl-2,6-octadienyl]-, N-[(2E)-3,7-Dimethyl-2,6-octadien-1-yl]cyclopropanecarboxamide, Fema 4267, n-3,7-dimethyl-2,6-octadienyl cyclopropylcarboxamide, (2e)-, cyclopropanecarboxamide, n-((2e)-3,7-dimethyl-2,6-octadien-1-yl)-, cyclopropanecarboxamide, n-((2e)-3,7-dimethyl-2,6-octadienyl)-, n-3,7-dimethyl-2,6-octadienylcyclopropylcarboxamide, n-(3,7-dimethyl-2,6-octadienyl)cyclopropanecarboxamide, (2e)-, n-((2e)-3,7-dimethyl-2,6-octadien-1-yl)cyclopropanecarboxamide, n-[(2e)-3,7-dimethyl-2,6-octadien-1-yl]cyclopropanecarboxamide, cyclopropanecarboxamide, n-[(2e)-3,7-dimethyl-2,6-octadien-1-yl]-.

Can N-3,7-Dimethyl-2,6-octadienyl cyclopropylcarboxamide be labeled natural?

The process decides for N-3,7-Dimethyl-2,6-octadienyl cyclopropylcarboxamide. It occurs in nature, so a natural-source, natural-process material is natural flavor in the US and synthetic N-3,7-Dimethyl-2,6-octadienyl cyclopropylcarboxamide is artificial. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.

United States
Natural or artificial, by process
European Union and UK
Natural only from natural material
Mercosur and Mexico
Natural or identical-to-natural

How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.

Regulatory status, with citations

United States

N-3,7-Dimethyl-2,6-octadienyl cyclopropylcarboxamide is FEMA GRAS under FEMA number 4267. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 16.095, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.

JECFA (WHO / FAO)

JECFA number 1779, evaluated at the 68th meeting in 2007. No safety concern at current levels of intake when used as a flavouring agent.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

Odor and taste

Odor: Herbaceous, green, slightly sweet, earthy.

Taste: Savory, slightly bitter, herbal.

Where it is used

N-3,7-Dimethyl-2,6-octadienyl cyclopropylcarboxamide is used in beverage, savory dishes, seasonings and snacks, typically as a fruity note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to N-3,7-Dimethyl-2,6-octadienyl cyclopropylcarboxamide by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
N-Cyclopropyl (E)-2,(Z)-6-nonadienamide408775%In nature
Nerolidol oxide453672%Not determined
4,5-Epoxy-(E)-2-decenal403753%In nature
Ethyl methyl-p-tolylglycidate375751%In nature
N-[(Ethoxycarbonyl)methyl)-p-menthane-3-carboxamide430951%Not determined

More amides in this index

N-(2-Methylcyclohexyl)-2,3,4,5,6-pentafluorobenzamide · (1R,2S,5R)-N-(4-Methoxyphenyl)-5-methyl-2-(1-methylethyl)cyclohexanecarboxamide · N-(2-Hydroxyethyl)galactonamide · N-Cyclopropyl (E)-2,(Z)-6-nonadienamide · 2-Isopropyl-N,2,3-trimethylbutyramide · (2S,5R)-N-[4-(2-Amino-2-oxoethyl)phenyl]-5-methyl-2-(propan-2-yl)cyclohexanecarboxamide

N-3,7-Dimethyl-2,6-octadienyl cyclopropylcarboxamide FAQ

Does N-3,7-Dimethyl-2,6-octadienyl cyclopropylcarboxamide have FEMA GRAS status?

N-3,7-Dimethyl-2,6-octadienyl cyclopropylcarboxamide holds FEMA GRAS status under FEMA number 4267. The Code of Federal Regulations lists it at 21 CFR 172.515.

How do I cite N-3,7-Dimethyl-2,6-octadienyl cyclopropylcarboxamide by FEMA or CAS number?

Cite N-3,7-Dimethyl-2,6-octadienyl cyclopropylcarboxamide as FEMA 4267 or CAS 744251-93-2; both point to the same entry. Its flavor category is fruity.

What does N-3,7-Dimethyl-2,6-octadienyl cyclopropylcarboxamide smell and taste like, and where is it used?

The odor of N-3,7-Dimethyl-2,6-octadienyl cyclopropylcarboxamide is herbaceous, green, slightly sweet, earthy. On the palate it is savory, slightly bitter, herbal. Typical uses are beverage, savory dishes, seasonings and snacks.

What did JECFA conclude about N-3,7-Dimethyl-2,6-octadienyl cyclopropylcarboxamide?

JECFA evaluated N-3,7-Dimethyl-2,6-octadienyl cyclopropylcarboxamide at the 68th meeting in 2007 under JECFA number 1779. The panel concluded: No safety concern at current levels of intake when used as a flavouring agent.

Can N-3,7-Dimethyl-2,6-octadienyl cyclopropylcarboxamide be used in the EU and UK?

Yes. FL 16.095 is the Union List entry for N-3,7-Dimethyl-2,6-octadienyl cyclopropylcarboxamide, annex I Part A, under Regulation 1334/2008, and the UK keeps the same list.

Can N-3,7-Dimethyl-2,6-octadienyl cyclopropylcarboxamide be labeled a natural flavor?

Nature makes N-3,7-Dimethyl-2,6-octadienyl cyclopropylcarboxamide, which is why the US label turns on process. A natural route gives natural flavor; synthesis gives artificial N-3,7-Dimethyl-2,6-octadienyl cyclopropylcarboxamide, same molecule. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic N-3,7-Dimethyl-2,6-octadienyl cyclopropylcarboxamide identical-to-natural.

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as N-3,7-DIMETHYL-2,6-OCTADIENYLCYCLOPROPYLCARBOXAMIDE under CAS 744251-93-2 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.