Flavor ingredient regulatory record

N-p-Benzene acetonitrile-menthane-carboxamide

N-p-Benzene acetonitrile-menthane-carboxamide is an amide in the fruity family, FEMA GRAS under FEMA number 4496 (CAS 852379-28-3). Its odor is sweet, fruity, floral, minty, herbal.

FEMA
4496
CAS
852379-28-3
JECFA
2009
EU FL
16.117
Formula
C19H26N2O

GRAS status: FEMA GRAS, publication 24. Recorded by FDA in the Substances Added to Food inventory under CAS 852379-28-3.

Structure

2D structure of N-p-Benzene acetonitrile-menthane-carboxamide
Structure of N-p-Benzene acetonitrile-menthane-carboxamide, C19H26N2O. Drawn from the canonical SMILES.

Identity

IUPAC name (1R,2S,5R)-N-[4-(cyanomethyl)phenyl]-5-methyl-2-propan-2-ylcyclohexane-1-carboxamide
CAS number 852379-28-3
FEMA number 4496
Molecular formula C19H26N2O
Molecular weight 298.43 g/mol
SMILES CC(C)[C@@H]1CC[C@@H](C)C[C@H]1C(=O)Nc1ccc(CC#N)cc1
InChIKey FPJRGEOLQICYQZ-FHLIZLRMSA-N
PubChem CID 44467796
Chemical class Amide

Also known as: Cyclohexanecarboxamide, N-[4-(cyanomethyl)phenyl]-5-methyl-2-(1-methylethyl)-, N-[4-(Cyanomethyl)phenyl]-5-methyl-2-(1-methylethyl)cyclohexanecarboxamide, N-(4-Cyanomethylphenyl)-p-menthanecarboxamide, Fema Gras 4496, evercool 180, n-p-benzeneacetonitrile menthanecarboxamide, n-para-benzene acetonitrile menthane carboxamide, n-p-benzeneacetonitrile menthanecarboxamide, (-)-, n-p-benzeneacetonitrile menthanecarboxamide, (1r,3r,4s)-, evercool g-180, cyclohexanecarboxamide, n-(4-(cyanomethyl)phenyl)-5-methyl-2-(1-methylethyl)-, (1r,2s,5r)-, cyanomethylphenyl menthane carboxamide.

Can N-p-Benzene acetonitrile-menthane-carboxamide be labeled natural?

Nature occurrence: Not yet found in nature (provisional).

Nature occurrence has not been settled for this substance, so the natural or artificial class is not stated here. The FEMA GRAS status does not depend on it.

Regulatory status, with citations

United States

N-p-Benzene acetonitrile-menthane-carboxamide is FEMA GRAS under FEMA number 4496. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 16.117, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.

JECFA (WHO / FAO)

JECFA number 2009, evaluated at the 73rd meeting in 2010. No safety concern at current levels of intake when used as a flavouring agent.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

Odor and taste

Odor: Sweet, fruity, floral, minty, herbal.

Where it is used

N-p-Benzene acetonitrile-menthane-carboxamide is used in beverage, confection, flavoring, personal care and candy, typically as a fruity note.

N-p-Benzene acetonitrile-menthane-carboxamide FAQ

Is N-p-Benzene acetonitrile-menthane-carboxamide on the FEMA GRAS list?

It is. FEMA number 4496 covers N-p-Benzene acetonitrile-menthane-carboxamide. It is also codified at 21 CFR 172.515.

What is the FEMA number for N-p-Benzene acetonitrile-menthane-carboxamide?

The FEMA number for N-p-Benzene acetonitrile-menthane-carboxamide is 4496 and its CAS registry number is 852379-28-3. FEMA files it in the fruity flavor category.

Is N-p-Benzene acetonitrile-menthane-carboxamide approved in the EU?

N-p-Benzene acetonitrile-menthane-carboxamide is on the EU Union List of flavouring substances as FL 16.117 (Annex I Part A) under Regulation 1334/2008.

Has JECFA evaluated N-p-Benzene acetonitrile-menthane-carboxamide?

Yes. JECFA number 2009, evaluated at the 73rd meeting in 2010. Conclusion: No safety concern at current levels of intake when used as a flavouring agent.

What is N-p-Benzene acetonitrile-menthane-carboxamide used for?

N-p-Benzene acetonitrile-menthane-carboxamide is described as sweet, fruity, floral, minty, herbal. It shows up in beverage, confection, flavoring, personal care and candy.

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as N-P-BENZENEACETONITRILEMENTHANECARBOXAMIDE under CAS 852379-28-3 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.