Flavor ingredient regulatory record
N-(2-(Pyridin-2-yl)ethyl)-3-p-menthanecarboxamide
N-(2-(Pyridin-2-yl)ethyl)-3-p-menthanecarboxamide is an amide in the herbal family, FEMA GRAS under FEMA number 4549 (CAS 847565-09-7). Its odor is earthy, herbal, green, slightly spicy.
- FEMA
- 4549
- CAS
- 847565-09-7
- JECFA
- 2008
- EU FL
- 16.118
- Formula
- C18H28N2O
GRAS status: FEMA GRAS, publication 24. Recorded by FDA in the Substances Added to Food inventory under CAS 862731-61-1.
Structure
Identity
Also known as: Cyclohexanecarboxamide, 5-methyl-2-(1-methylethyl)-N-[2-(2-pyridinyl)ethyl]-, (1R,2S,5R)-rel-, rel-(1R,2S,5R)-5-Methyl-2-(1-methylethyl)-N-[2-(2-pyridinyl)ethyl]cyclohexanecarboxamide, (1R,2S,5R)-N-(2-(Pyridin-2-yl)ethyl)menthylcarboxamide, 5-methyl-2-(propan-2-yl)-n-[2-(pyridin-2-yl)ethyl]cyclohexane-1-carboxamide.
Can N-(2-(Pyridin-2-yl)ethyl)-3-p-menthanecarboxamide be labeled natural?
Nature occurrence: Not yet found in nature (provisional).
Nature occurrence has not been settled for this substance, so the natural or artificial class is not stated here. The FEMA GRAS status does not depend on it.
Regulatory status, with citations
United States
N-(2-(Pyridin-2-yl)ethyl)-3-p-menthanecarboxamide is FEMA GRAS under FEMA number 4549. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
Listed on the Union List of flavouring substances as FL 16.118, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.
JECFA (WHO / FAO)
JECFA number 2008, evaluated at the 73rd meeting in 2010. No safety concern at current levels of intake when used as a flavouring agent.
Other US flags
Not on the California Proposition 65 list.
Odor and taste
Odor: Earthy, herbal, green, slightly spicy.
Where it is used
N-(2-(Pyridin-2-yl)ethyl)-3-p-menthanecarboxamide is used in savory dishes, seasoning blends, snack foods and sauces, typically as a herbal note.
Structurally similar flavor ingredients
Flavor ingredients with a GRAS determination closest to N-(2-(Pyridin-2-yl)ethyl)-3-p-menthanecarboxamide by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.
| Material | FEMA | Similarity | Occurrence |
|---|---|---|---|
| N1-(2-Methoxy-4-methylbenzyl)-N2-(2-(5-methylpyridin-2-yl)ethyl)oxalamide | 4234 | 79% | Not determined |
| (1R,2S,5R)-N-(4-Methoxyphenyl)-5-methyl-2-(1-methylethyl)cyclohexanecarboxamide | 4681 | 79% | Not determined |
| N1-(2,4-Dimethoxybenzyl)-N2-(2-(pyridin-2-yl)ethyl)oxalamide | 4233 | 78% | Not determined |
| N1-(2-Methoxy-4-methylbenzyl)-N2-(2-(pyridin-2-yl)ethyl)oxalamide | 4231 | 77% | Not determined |
| Capsaicin | 3404 | 77% | In nature |
More amides in this index
N-3,7-Dimethyl-2,6-octadienyl cyclopropylcarboxamide · 2-(4-Methylphenoxy)-N-(1H-pyrazol-3-yl)-N-(thiophen-2-ylmethyl)acetamide · (1R,2S,5R)-N-(4-Methoxyphenyl)-5-methyl-2-(1-methylethyl)cyclohexanecarboxamide · N-p-Benzene acetonitrile-menthane-carboxamide · Nonanoyl 4-hydroxy-3-methoxybenzylamide · Butyramide
N-(2-(Pyridin-2-yl)ethyl)-3-p-menthanecarboxamide FAQ
Does N-(2-(Pyridin-2-yl)ethyl)-3-p-menthanecarboxamide have FEMA GRAS status?
N-(2-(Pyridin-2-yl)ethyl)-3-p-menthanecarboxamide holds FEMA GRAS status under FEMA number 4549. The Code of Federal Regulations lists it at 21 CFR 172.515.
How do I cite N-(2-(Pyridin-2-yl)ethyl)-3-p-menthanecarboxamide by FEMA or CAS number?
Cite N-(2-(Pyridin-2-yl)ethyl)-3-p-menthanecarboxamide as FEMA 4549 or CAS 847565-09-7; both point to the same entry. Its flavor category is herbal.
What does N-(2-(Pyridin-2-yl)ethyl)-3-p-menthanecarboxamide smell and taste like, and where is it used?
The odor of N-(2-(Pyridin-2-yl)ethyl)-3-p-menthanecarboxamide is earthy, herbal, green, slightly spicy. Typical uses are savory dishes, seasoning blends, snack foods and sauces.
What did JECFA conclude about N-(2-(Pyridin-2-yl)ethyl)-3-p-menthanecarboxamide?
JECFA evaluated N-(2-(Pyridin-2-yl)ethyl)-3-p-menthanecarboxamide at the 73rd meeting in 2010 under JECFA number 2008. The panel concluded: No safety concern at current levels of intake when used as a flavouring agent.
Can N-(2-(Pyridin-2-yl)ethyl)-3-p-menthanecarboxamide be used in the EU and UK?
Yes. FL 16.118 is the Union List entry for N-(2-(Pyridin-2-yl)ethyl)-3-p-menthanecarboxamide, annex I Part A, under Regulation 1334/2008, and the UK keeps the same list.
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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as N-(2-(PYRIDIN-2-YL)ETHYL)-3-P-MENTHANECARBOXAMIDE under CAS 862731-61-1 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.