Flavor ingredient regulatory record

N-(Heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide

N-(Heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide is an amide in the fruity family, FEMA GRAS under FEMA number 4232 (CAS 745047-51-2).

FEMA
4232
CAS
745047-51-2
JECFA
1767
EU FL
16.098
Formula
C15H21NO3

GRAS status: FEMA GRAS, publication 22. Recorded by FDA in the Substances Added to Food inventory under CAS 745047-51-2.

Structure

2D structure of N-(Heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide
Structure of N-(Heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide, C15H21NO3. Drawn from the canonical SMILES.

Identity

IUPAC name N-heptan-4-yl-1,3-benzodioxole-5-carboxamide
CAS number 745047-51-2
FEMA number 4232
Molecular formula C15H21NO3
Molecular weight 263.34 g/mol
SMILES CCCC(CCC)NC(=O)c1ccc2c(c1)OCO2
InChIKey YOBNUUGTIXQSPD-UHFFFAOYSA-N
PubChem CID 22831877
FDA UNII 4E1875N4ZT
EPA DTXSID DTXSID90225503
Chemical class Amide

Also known as: 1,3-Benzodioxole-5-carboxamide, N-(1-propylbutyl)-, N-(1-Propylbutyl)-1,3-benzodioxole-5-carboxamide, n-(1-propylbutyl)-1,3-benzodioxole-5-carboxamide, n-(heptan-4-yl)benzo(d)(1,3)dioxole-5-carboxamide, 1,3-benzodioxole-5-carboxamide, n-(1-propylbutyl)-, n-(heptan-4-yl)-2h-1,3-benzodioxole-5-carboxamide, n-(heptan-4-yl)benzo(d)(1,3)dioxole-5-carboxamide [fifh], n-(heptan-4-yl)benzo(d)(1,3)dioxole-5-carboxamide [fhfi], n-(heptan-4-yl)benzo(d)(1,3)dioxole-5-carboxamide (fifh), 1,3-benzodioxole-5-carboxamide,n-(1-propylbutyl)-, n-heptan-4-yl-1,3-benzodioxole-5-carboxamide, ex-a3060.

Can N-(Heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide be labeled natural?

Nature occurrence: Not yet found in nature (provisional).

Nature occurrence has not been settled for this substance, so the natural or artificial class is not stated here. The FEMA GRAS status does not depend on it.

Regulatory status, with citations

United States

N-(Heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide is FEMA GRAS under FEMA number 4232. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 16.098, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.

JECFA (WHO / FAO)

JECFA number 1767, evaluated at the 68th meeting in 2007. no safety concern at current levels of intake.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

Odor and taste

Taste: Sweet, umami, savory.

Where it is used

N-(Heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide is used in beverage, confection, savory snacks and seasonings, typically as a fruity note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to N-(Heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

More amides in this index

Nonanoyl 4-hydroxy-3-methoxybenzylamide · N-p-Benzene acetonitrile-menthane-carboxamide · N1-(2-Methoxy-4-methylbenzyl)-N2-(2-(5-methylpyridin-2-yl)ethyl)oxalamide · 2-(4-Methylphenoxy)-N-(1H-pyrazol-3-yl)-N-(thiophen-2-ylmethyl)acetamide · (2S,5R)-N-[4-(2-Amino-2-oxoethyl)phenyl]-5-methyl-2-(propan-2-yl)cyclohexanecarboxamide · 2-Isopropyl-N,2,3-trimethylbutyramide

N-(Heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide FAQ

Is N-(Heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide on the FEMA GRAS list?

It is. FEMA number 4232 covers N-(Heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide. It is also codified at 21 CFR 172.515.

What is the FEMA number for N-(Heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide?

The FEMA number for N-(Heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide is 4232 and its CAS registry number is 745047-51-2. FEMA files it in the fruity flavor category.

Is N-(Heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide approved in the EU?

N-(Heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide is on the EU Union List of flavouring substances as FL 16.098 (Annex I Part A) under Regulation 1334/2008.

Has JECFA evaluated N-(Heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide?

Yes. JECFA number 1767, evaluated at the 68th meeting in 2007. Conclusion: no safety concern at current levels of intake.

Ingredient lookup

Check an ingredient

Start typing to search the ingredient corpus.

Or browse every ingredient page, A to Z.

Guides: What Is FEMA GRAS? · Natural vs artificial · Filing a GRAS notification

Check N-(Heptan-4-yl)benzo[d][1,3]dioxole-5-carboxamide in a formula

Screened against FEMA GRAS, 21 CFR and EU rules as you build. Free to start.

Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as N-(HEPTAN-4-YL)BENZO[D][1,3]DIOXOLE-5-CARBOXAMIDE under CAS 745047-51-2 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.