Flavor ingredient regulatory record
p,alpha-Dimethylstyrene
p,alpha-Dimethylstyrene is an alkene in the fruity family, FEMA GRAS under FEMA number 3144 (CAS 1195-32-0). Its odor is sweet, fruity, floral, slightly spicy.
- FEMA
- 3144
- CAS
- 1195-32-0
- JECFA
- 1333
- EU FL
- 01.010
- Formula
- C10H12
- EC
- 214-795-9
GRAS status: FEMA GRAS, publication 4. Recorded by FDA in the Substances Added to Food inventory under CAS 1195-32-0.
Structure
Identity
Also known as: Benzene, 1-methyl-4-(1-methylethenyl)-, Styrene, p,α-dimethyl-, 1-Methyl-4-(1-methylethenyl)benzene, 1-Methyl-4-isopropenylbenzene, p-Methyl-α-methylstyrene, p,α-Dimethylstyrene, p-Isopropenyltoluene, α,p-Dimethylstyrene, 4-Methyl-α-methylstyrene, α,4-Dimethylstyrene, 2-(p-Methylphenyl)propene, 2-p-Tolylpropene.
Can p,alpha-Dimethylstyrene be labeled natural?
p,alpha-Dimethylstyrene occurs in nature, so the label depends on the route: p,alpha-Dimethylstyrene won from a natural source by a physical, enzymatic or microbiological process is natural flavor in the United States, and synthesized p,alpha-Dimethylstyrene is artificial. The EU and UK grant the natural claim only to that natural route; Mercosur and Mexico call synthetic material identical-to-natural.
- United States
- Natural or artificial, by process
- European Union and UK
- Natural only from natural material
- Mercosur and Mexico
- Natural or identical-to-natural
How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.
Regulatory status, with citations
United States
p,alpha-Dimethylstyrene is FEMA GRAS under FEMA number 3144. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
Listed on the Union List of flavouring substances as FL 01.010, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.
JECFA (WHO / FAO)
JECFA number 1333, evaluated at the 63rd meeting in 2004. no safety concern at current levels of intake.
Other US flags
Not on the California Proposition 65 list.
TSCA Inventory status
A flavor ingredient is also an industrial chemical. p,alpha-Dimethylstyrene appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 1195-32-0, where EPA names it Benzene, 1-methyl-4-(1-methylethenyl)-.
Active in US commerce
EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.
EPA publishes no regulatory flags on this listing. What the flags mean.
From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.
Odor and taste
Odor: Sweet, fruity, floral, slightly spicy.
Where it is used
p,alpha-Dimethylstyrene is used in beverage, confection, flavoring agents, fragrance and food products, typically as a fruity note.
Structurally similar flavor ingredients
Flavor ingredients with a GRAS determination closest to p,alpha-Dimethylstyrene by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.
| Material | FEMA | Similarity | Occurrence |
|---|---|---|---|
| p-Mentha-1,3-diene | 3558 | 73% | In nature |
| Terpinolene | 3046 | 73% | In nature |
| p-Mentha-1,4-diene | 3559 | 72% | In nature |
| alpha-Phellandrene | 2856 | 71% | In nature |
More alkenes in this index
2,4-Nonadiene · 1,3,5,7-Undecatetraene · 4-Methyl-cis-2-pentene · cis- and trans-1-Methoxy-1-decene · 1-Nonene · 1-Octene
p,alpha-Dimethylstyrene FAQ
Is p,alpha-Dimethylstyrene FEMA GRAS?
Yes. The FEMA Expert Panel lists p,alpha-Dimethylstyrene as GRAS under FEMA number 3144. It is also codified at 21 CFR 172.515.
What are the FEMA and CAS numbers for p,alpha-Dimethylstyrene?
p,alpha-Dimethylstyrene is FEMA 3144, CAS 1195-32-0. FEMA files it in the fruity flavor category.
Does p,alpha-Dimethylstyrene count as natural in the US and the EU?
Since p,alpha-Dimethylstyrene is found in nature, US labeling follows how it was obtained: natural flavor from a natural source and a natural process, artificial when p,alpha-Dimethylstyrene is synthesized. The EU and UK grant the natural claim only to that natural route; Mercosur and Mexico call synthetic material identical-to-natural.
Is p,alpha-Dimethylstyrene on the EU Union List?
p,alpha-Dimethylstyrene is on the EU Union List of flavouring substances as FL 01.010 (Annex I Part A) under Regulation 1334/2008.
Has JECFA evaluated p,alpha-Dimethylstyrene?
Yes. JECFA number 1333, evaluated at the 63rd meeting in 2004. Conclusion: no safety concern at current levels of intake.
How is p,alpha-Dimethylstyrene described, and where does it show up?
Flavorists describe p,alpha-Dimethylstyrene as sweet, fruity, floral, slightly spicy. It is used in beverage, confection, flavoring agents, fragrance and food products.
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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as P,ALPHA-DIMETHYLSTYRENE under CAS 1195-32-0 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.