Flavor ingredient regulatory record
trans-2-Hexenal propylene glycol acetal
trans-2-Hexenal propylene glycol acetal is an aldehyde in the fruity family, FEMA GRAS under FEMA number 4272 (CAS 94089-21-1). Its odor is green, fruity, fresh, apple, grassy.
- FEMA
- 4272
- CAS
- 94089-21-1
- JECFA
- 1801
- Formula
- C9H16O2
GRAS status: FEMA GRAS, publication 23. Recorded by FDA in the Substances Added to Food inventory under CAS 648434-55-3.
Structure
Identity
Also known as: 1,3-Dioxolane, 4-methyl-2-(1E)-1-penten-1-yl-, 1,3-Dioxolane, 4-methyl-2-(1-pentenyl)-, (E)-, 1,3-Dioxolane, 4-methyl-2-(1E)-1-pentenyl-, 4-Methyl-2-(1E)-1-penten-1-yl-1,3-dioxolane, (e)-4-methyl-2-(pent-1-enyl)-1,3-dioxolane, 4-methyl-2-(1e)-1-penten-1-yl-1,3-dioxolane, (e)-4-methyl-2-(pent-1-en-1-yl)-1,3-dioxolane, trans-2-hexenal propyleneglycol acetal, 4-methyl-2-[(e)-pent-1-enyl]-1,3-dioxolane, 1,3-dioxolane, 4-methyl-2-(1-pentenyl)-, (e)-, 4-methyl-2-[(1e)-pent-1-en-1-yl]-1,3-dioxolane, 2-hexenal propylene glycol acetal.
Can trans-2-Hexenal propylene glycol acetal be labeled natural?
trans-2-Hexenal propylene glycol acetal occurs in nature, so the label depends on the route: trans-2-Hexenal propylene glycol acetal won from a natural source by a physical, enzymatic or microbiological process is natural flavor in the United States, and synthesized trans-2-Hexenal propylene glycol acetal is artificial. The EU and UK grant the natural claim only to that natural route; Mercosur and Mexico call synthetic material identical-to-natural.
- United States
- Natural or artificial, by process
- European Union and UK
- Natural only from natural material
- Mercosur and Mexico
- Natural or identical-to-natural
How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.
Regulatory status, with citations
United States
trans-2-Hexenal propylene glycol acetal is FEMA GRAS under FEMA number 4272. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
No EU FL number is on file for trans-2-Hexenal propylene glycol acetal. That is not a finding either way. The Union List covers defined flavouring substances, so natural complex materials are handled as flavouring preparations under Parts B to F and never receive a number, and substances used as additives sit under Regulation 1333/2008 instead. Confirm the position before EU or UK use.
JECFA (WHO / FAO)
JECFA number 1801, evaluated at the 69th meeting in 2008. No safety concern at current levels of intake when used as a flavouring agent.
Other US flags
Not on the California Proposition 65 list.
Odor and taste
Odor: Green, fruity, fresh, apple, grassy.
Where it is used
trans-2-Hexenal propylene glycol acetal is used in beverage, confection, fruit flavors, bakery and savory dishes, typically as a fruity note.
Structurally similar flavor ingredients
Flavor ingredients with a GRAS determination closest to trans-2-Hexenal propylene glycol acetal by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.
| Material | FEMA | Similarity | Occurrence |
|---|---|---|---|
| trans-2-Hexenal glyceryl acetal | 4273 | 85% | Not determined |
| 5-Pentyl-3H-furan-2-one | 4323 | 83% | In nature |
| Hexanal butane-2,3-diol acetal | 4384 | 82% | Not determined |
| Heptanal propyleneglycol acetal | 4368 | 69% | Not determined |
| gamma-Nonalactone | 2781 | 68% | In nature |
More aldehydes in this index
4-Methyl-2-(methylthiomethyl)-2-hexenal · 3-(p-Isopropylphenyl)propionaldehyde · 6-Methylheptanal · (+/-)-2-(5-Methyl-5-vinyl-tetrahydrofuran-2-yl)propionaldehyde · Butyraldehyde · 2-(Methylthio)methyl-2-butenal
trans-2-Hexenal propylene glycol acetal FAQ
Is trans-2-Hexenal propylene glycol acetal FEMA GRAS?
Yes. The FEMA Expert Panel lists trans-2-Hexenal propylene glycol acetal as GRAS under FEMA number 4272. It is also codified at 21 CFR 172.515.
What are the FEMA and CAS numbers for trans-2-Hexenal propylene glycol acetal?
trans-2-Hexenal propylene glycol acetal is FEMA 4272, CAS 94089-21-1. FEMA files it in the fruity flavor category.
Does trans-2-Hexenal propylene glycol acetal count as natural in the US and the EU?
Since trans-2-Hexenal propylene glycol acetal is found in nature, US labeling follows how it was obtained: natural flavor from a natural source and a natural process, artificial when trans-2-Hexenal propylene glycol acetal is synthesized. The EU and UK grant the natural claim only to that natural route; Mercosur and Mexico call synthetic material identical-to-natural.
Is trans-2-Hexenal propylene glycol acetal approved in the EU?
No EU FL number is on file for trans-2-Hexenal propylene glycol acetal. It has a JECFA evaluation (JECFA 1801), which the EU list draws on, but the Union List entry itself should be confirmed before EU use.
Has JECFA evaluated trans-2-Hexenal propylene glycol acetal?
Yes. JECFA number 1801, evaluated at the 69th meeting in 2008. Conclusion: No safety concern at current levels of intake when used as a flavouring agent.
How is trans-2-Hexenal propylene glycol acetal described, and where does it show up?
Flavorists describe trans-2-Hexenal propylene glycol acetal as green, fruity, fresh, apple, grassy. It is used in beverage, confection, fruit flavors, bakery and savory dishes.
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Guides: What Is FEMA GRAS? · Natural vs artificial · Filing a GRAS notification
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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as (+/-)-TRANS- AND CIS-2-HEXENAL PROPYLENE GLYCOL ACETAL under CAS 648434-55-3 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.