Flavor ingredient regulatory record

(+/-)-1-Cyclohexylethanol

(+/-)-1-Cyclohexylethanol is an alcohol in the fruity family, FEMA GRAS under FEMA number 4794 (CAS 1193-81-3). Its odor is sweet, floral, fruity, slightly woody.

FEMA
4794
CAS
1193-81-3
JECFA
2221
Formula
C8H16O
EC
214-780-7

GRAS status: FEMA GRAS. Source: FEMA Flavor Ingredient Library.

Structure

2D structure of (+/-)-1-Cyclohexylethanol
Structure of (+/-)-1-Cyclohexylethanol, C8H16O. Drawn from the canonical SMILES.

Identity

IUPAC name 1-cyclohexylethanol
CAS number 1193-81-3
FEMA number 4794
Molecular formula C8H16O
Molecular weight 128.22 g/mol
SMILES CC(O)C1CCCCC1
InChIKey JMSUNAQVHOHLMX-UHFFFAOYSA-N
PubChem CID 137829
EC number 214-780-7
FDA UNII G247D91I97
EPA DTXSID DTXSID7047643
Chemical class Alcohol
Boiling point 189 °C
Flash point 80 °C

Also known as: Cyclohexanemethanol, α-methyl-, α-Methylcyclohexanemethanol, Ethanol, 1-cyclohexyl-, Methanol, cyclohexylmethyl-, Cyclohexylmethylcarbinol, 1-Cyclohexylethanol, 1-Cyclohexyl-1-ethanol, Methylcyclohexylcarbinol, Methylcyclohexylmethanol, 1-Cyclohexane-1-ethanol, (±)-1-Cyclohexylethanol, (1-Hydroxyethyl)cyclohexane.

Can (+/-)-1-Cyclohexylethanol be labeled natural?

Nature occurrence: Not yet found in nature (provisional).

Nature occurrence has not been settled for this substance, so the natural or artificial class is not stated here. The FEMA GRAS status does not depend on it.

Regulatory status, with citations

United States

(+/-)-1-Cyclohexylethanol is FEMA GRAS under FEMA number 4794. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

No EU FL number is on file for (+/-)-1-Cyclohexylethanol. That is not a finding either way. The Union List covers defined flavouring substances, so natural complex materials are handled as flavouring preparations under Parts B to F and never receive a number, and substances used as additives sit under Regulation 1333/2008 instead. Confirm the position before EU or UK use.

JECFA (WHO / FAO)

JECFA number 2221, evaluated at the 82nd meeting in 2016. no safety concern at current levels of intake.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

TSCA Inventory status

A flavor ingredient is also an industrial chemical. (+/-)-1-Cyclohexylethanol appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 1193-81-3, where EPA names it Cyclohexanemethanol, .alpha.-methyl-.

Active in US commerce

EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.

EPA publishes no regulatory flags on this listing. What the flags mean.

From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.

Odor and taste

Odor: Sweet, floral, fruity, slightly woody.

Taste: Sweet, smooth, mild.

Where it is used

(+/-)-1-Cyclohexylethanol is used in beverage, confection, flavoring agents and perfumes, typically as a fruity note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to (+/-)-1-Cyclohexylethanol by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
3-Methyl-1-pentanol376286%In nature
Hexan-3-ol335185%In nature

More alcohols in this index

2-Pentanol · 2-Octen-4-ol · 4-Hexen-1-ol · Tetrahydrofurfuryl alcohol · 2,4-Hexadien-1-ol · 2-Ethyl-1-hexanol

(+/-)-1-Cyclohexylethanol FAQ

Is (+/-)-1-Cyclohexylethanol FEMA GRAS?

Yes. The FEMA Expert Panel lists (+/-)-1-Cyclohexylethanol as GRAS under FEMA number 4794. It is also codified at 21 CFR 172.515.

What are the FEMA and CAS numbers for (+/-)-1-Cyclohexylethanol?

(+/-)-1-Cyclohexylethanol is FEMA 4794, CAS 1193-81-3. FEMA files it in the fruity flavor category.

Is (+/-)-1-Cyclohexylethanol approved in the EU?

No EU FL number is on file for (+/-)-1-Cyclohexylethanol. It has a JECFA evaluation (JECFA 2221), which the EU list draws on, but the Union List entry itself should be confirmed before EU use.

Has JECFA evaluated (+/-)-1-Cyclohexylethanol?

Yes. JECFA number 2221, evaluated at the 82nd meeting in 2016. Conclusion: no safety concern at current levels of intake.

How is (+/-)-1-Cyclohexylethanol described, and where does it show up?

Flavorists describe (+/-)-1-Cyclohexylethanol as sweet, floral, fruity, slightly woody. On the palate it is sweet, smooth, mild. It is used in beverage, confection, flavoring agents and perfumes.

Ingredient lookup

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Guides: What Is FEMA GRAS? · Natural vs artificial · Filing a GRAS notification

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Sources and attribution. The FEMA number and GRAS status on this page name a conclusion reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States. FDA does not list this substance by FEMA number in its Substances Added to Food inventory. Its identity is attested by EPA TSCA Chemical Substance Inventory, matched on CAS 1193-81-3.

FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.