Flavor ingredient regulatory record
2,4-Dihydroxybenzoic acid
2,4-Dihydroxybenzoic acid is an acid in the fruity family, FEMA GRAS under FEMA number 3798 (CAS 89-86-1). Its odor is sweet, fruity, floral, tangy, aromatic.
- FEMA
- 3798
- CAS
- 89-86-1
- JECFA
- 908
- EU FL
- 08.076
- Formula
- C7H6O4
- EC
- 201-946-9
GRAS status: FEMA GRAS, publication 17. Recorded by FDA in the Substances Added to Food inventory under CAS 89-86-1.
Structure
Identity
Also known as: Benzoic acid, 2,4-dihydroxy-, β-Resorcylic acid, 4-Hydroxysalicylic acid, p-Hydroxysalicylic acid, 4-Carboxyresorcinol, β-Resorcinolic acid, Coupler 320, NSC 13564, NSC 4740, beta-resorcylic acid, 4-hydroxysalicylic acid, 4-carboxyresorcinol.
Can 2,4-Dihydroxybenzoic acid be labeled natural?
Since 2,4-Dihydroxybenzoic acid is found in nature, US labeling follows how it was obtained: natural flavor from a natural source and a natural process, artificial when 2,4-Dihydroxybenzoic acid is synthesized. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.
- United States
- Natural or artificial, by process
- European Union and UK
- Natural only from natural material
- Mercosur and Mexico
- Natural or identical-to-natural
How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.
Regulatory status, with citations
United States
2,4-Dihydroxybenzoic acid is FEMA GRAS under FEMA number 3798. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
Listed on the Union List of flavouring substances as FL 08.076, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.
JECFA (WHO / FAO)
JECFA number 908, evaluated at the 57th meeting in 2001. No safety concern at current levels of intake when used as a flavouring agent.
Other US flags
Not on the California Proposition 65 list.
TSCA Inventory status
A flavor ingredient is also an industrial chemical. 2,4-Dihydroxybenzoic acid appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 89-86-1, where EPA names it Benzoic acid, 2,4-dihydroxy-.
Active in US commerce
EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.
EPA publishes no regulatory flags on this listing. What the flags mean.
From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.
Odor and taste
Odor: Sweet, fruity, floral, tangy, aromatic.
Taste: Sour, tangy, slightly bitter.
Where it is used
2,4-Dihydroxybenzoic acid is used in beverage, confection, fruit flavors, sauces and dressings, typically as a fruity note.
Structurally similar flavor ingredients
Flavor ingredients with a GRAS determination closest to 2,4-Dihydroxybenzoic acid by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.
| Material | FEMA | Similarity | Occurrence |
|---|---|---|---|
| 4-Hydroxybenzoic acid | 3986 | 91% | In nature |
| 4-Hydroxy-3-methoxy benzoic acid | 3988 | 78% | In nature |
| 4-Hydroxyacetophenone | 4330 | 77% | In nature |
| 3,4-Dihydroxybenzoic acid | 4430 | 76% | In nature |
| 4-Hydroxybenzyl alcohol | 3987 | 74% | In nature |
More acids in this index
Methyl-3-pentenoic acid · 3,7-Dimethyl-6-octenoic acid · Heptanoic acid · 4-Pentenoic acid · 3-Methyl-2-oxopentanoic acid · Mixture of Ricinoleic acid, Linoleic acid, and Oleic acid
2,4-Dihydroxybenzoic acid FAQ
Is 2,4-Dihydroxybenzoic acid FEMA GRAS?
Yes. The FEMA Expert Panel lists 2,4-Dihydroxybenzoic acid as GRAS under FEMA number 3798. It is also codified at 21 CFR 172.515.
What are the FEMA and CAS numbers for 2,4-Dihydroxybenzoic acid?
2,4-Dihydroxybenzoic acid is FEMA 3798, CAS 89-86-1. FEMA files it in the fruity flavor category.
Does 2,4-Dihydroxybenzoic acid count as natural in the US and the EU?
2,4-Dihydroxybenzoic acid occurs in nature, so the label depends on the route: 2,4-Dihydroxybenzoic acid won from a natural source by a physical, enzymatic or microbiological process is natural flavor in the United States, and synthesized 2,4-Dihydroxybenzoic acid is artificial. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic 2,4-Dihydroxybenzoic acid identical-to-natural.
Is 2,4-Dihydroxybenzoic acid on the EU Union List?
2,4-Dihydroxybenzoic acid is on the EU Union List of flavouring substances as FL 08.076 (Annex I Part A) under Regulation 1334/2008.
Has JECFA evaluated 2,4-Dihydroxybenzoic acid?
Yes. JECFA number 908, evaluated at the 57th meeting in 2001. Conclusion: No safety concern at current levels of intake when used as a flavouring agent.
How is 2,4-Dihydroxybenzoic acid described, and where does it show up?
Flavorists describe 2,4-Dihydroxybenzoic acid as sweet, fruity, floral, tangy, aromatic. On the palate it is sour, tangy, slightly bitter. It is used in beverage, confection, fruit flavors, sauces and dressings.
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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as 2,4-DIHYDROXYBENZOIC ACID under CAS 89-86-1 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.