Flavor ingredient regulatory record

2-Acetyl-3,5-dimethylfuran

2-Acetyl-3,5-dimethylfuran is a furan in the fruity family, FEMA GRAS under FEMA number 4071 (CAS 22940-86-9). Its odor is sweet, nutty, caramel, toasted, popcorn.

FEMA
4071
CAS
22940-86-9
JECFA
1505
EU FL
13.101
Formula
C8H10O2
EC
607-185-2

GRAS status: FEMA GRAS, publication 22. Recorded by FDA in the Substances Added to Food inventory under CAS 22940-86-9.

Structure

2D structure of 2-Acetyl-3,5-dimethylfuran
Structure of 2-Acetyl-3,5-dimethylfuran, C8H10O2. Drawn from the canonical SMILES.

Identity

IUPAC name 1-(3,5-dimethylfuran-2-yl)ethanone
CAS number 22940-86-9
FEMA number 4071
Molecular formula C8H10O2
Molecular weight 138.17 g/mol
SMILES CC(=O)c1oc(C)cc1C
InChIKey SQWQZVDNBPEROH-UHFFFAOYSA-N
PubChem CID 579675
EC number 607-185-2
FDA UNII 1MFL8Z7ZBB
EPA DTXSID DTXSID20177485
Chemical class Furan
Boiling point 195 °C
Flash point 83 °C

Also known as: Ethanone, 1-(3,5-dimethyl-2-furanyl)-, Ketone, 3,5-dimethyl-2-furyl methyl, 1-(3,5-Dimethyl-2-furanyl)ethanone, 1-(3,5-Dimethylfuran-2-yl)ethan-1-one, ethanone, 1-(3,5-dimethyl-2-furanyl)-, 1-(3,5-dimethylfuran-2-yl)ethan-1-one, ketone, 3,5-dimethyl-2-furyl methyl, 3,5-dimethyl-2-furyl methyl ketone, 2-acetyl-3,5-dimethylfuran [fhfi], 1-(3,5-dimethylfuran-2-yl)ethanone, 1-(3,5-dimethyl-2-furyl)ethanone, 2-acetyl-3,5-dimethyl furan.

Can 2-Acetyl-3,5-dimethylfuran be labeled natural?

Nature occurrence: Not yet found in nature (provisional).

Nature occurrence has not been settled for this substance, so the natural or artificial class is not stated here. The FEMA GRAS status does not depend on it.

Regulatory status, with citations

United States

2-Acetyl-3,5-dimethylfuran is FEMA GRAS under FEMA number 4071. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 13.101, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.

JECFA (WHO / FAO)

JECFA number 1505, evaluated at the 86th meeting in 2018. No safety concern at current levels of intake when used as a flavouring agent.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

Odor and taste

Odor: Sweet, nutty, caramel, toasted, popcorn.

Taste: Sweet, nutty, slightly caramelized.

Where it is used

2-Acetyl-3,5-dimethylfuran is used in beverage, confection, bakery and snack foods, typically as a fruity note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to 2-Acetyl-3,5-dimethylfuran by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
2-Acetyl-5-methylfuran360982%In nature
2-Acetyl-3-methylpyrazine396482%In nature
2,5-Dimethyl-4-ethyloxazole439576%In nature
2-Furyl methyl ketone316373%In nature
5-Methylfurfuryl alcohol454470%In nature

More furans in this index

Furfural · 2-Methyl-3-(methylthio)furan · 5-Methyl-3(2H)-furanone · 2-Butyrylfuran · Ethyl furfuryl ether · 2-Pentanoylfuran

2-Acetyl-3,5-dimethylfuran FAQ

Is 2-Acetyl-3,5-dimethylfuran FEMA GRAS?

Yes. The FEMA Expert Panel lists 2-Acetyl-3,5-dimethylfuran as GRAS under FEMA number 4071. The Code of Federal Regulations lists it at 21 CFR 172.515.

What are the FEMA and CAS numbers for 2-Acetyl-3,5-dimethylfuran?

2-Acetyl-3,5-dimethylfuran is FEMA 4071, CAS 22940-86-9. Its flavor category is fruity.

How is 2-Acetyl-3,5-dimethylfuran described, and where does it show up?

Flavorists describe 2-Acetyl-3,5-dimethylfuran as sweet, nutty, caramel, toasted, popcorn. On the palate it is sweet, nutty, slightly caramelized. It is used in beverage, confection, bakery and snack foods.

What did JECFA conclude about 2-Acetyl-3,5-dimethylfuran?

JECFA evaluated 2-Acetyl-3,5-dimethylfuran at the 86th meeting in 2018 under JECFA number 1505. The panel concluded: No safety concern at current levels of intake when used as a flavouring agent.

Is 2-Acetyl-3,5-dimethylfuran on the EU Union List?

Yes. FL 13.101 is the Union List entry for 2-Acetyl-3,5-dimethylfuran, annex I Part A, under Regulation 1334/2008, and the UK keeps the same list.

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as 2-ACETYL-3,5-DIMETHYLFURAN under CAS 22940-86-9 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.