Flavor ingredient regulatory record
2-Propionylpyrrole
2-Propionylpyrrole is a ketone in the nutty family, FEMA GRAS under FEMA number 3614 (CAS 1073-26-3). Its odor is nutty, roasted, chocolate, earthy, sweet.
- FEMA
- 3614
- CAS
- 1073-26-3
- JECFA
- 1319
- EU FL
- 14.068
- Formula
- C7H9NO
- EC
- 214-026-7
GRAS status: FEMA GRAS, publication 12. Recorded by FDA in the Substances Added to Food inventory under CAS 1073-26-3.
Structure
Identity
Also known as: 1-Propanone, 1-(1H-pyrrol-2-yl)-, 1-Propanone, 1-pyrrol-2-yl-, 1-Propanone, 1-(2-pyrryl)-, 1-(1H-Pyrrol-2-yl)-1-propanone, 2-Propanoylpyrrole, NSC 81353, 1-(1H-Pyrrol-2-yl)propan-1-one, 1-(1h-pyrrol-2-yl)propan-1-one, ethyl 2-pyrrolyl ketone, 2-pyrryl ethyl ketone, alpha-propionylpyrrole, alpha-pyrryl ethyl ketone.
Can 2-Propionylpyrrole be labeled natural?
Nature occurrence: Not yet found in nature (provisional).
Nature occurrence has not been settled for this substance, so the natural or artificial class is not stated here. The FEMA GRAS status does not depend on it.
Regulatory status, with citations
United States
2-Propionylpyrrole is FEMA GRAS under FEMA number 3614. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
Listed on the Union List of flavouring substances as FL 14.068, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.
JECFA (WHO / FAO)
JECFA number 1319.
Other US flags
Not on the California Proposition 65 list.
Odor and taste
Odor: Nutty, roasted, chocolate, earthy, sweet.
Taste: Nutty, sweet, creamy.
Where it is used
2-Propionylpyrrole is used in baked goods, confectionery, snacks and dairy, typically as a nutty note.
Structurally similar flavor ingredients
Flavor ingredients with a GRAS determination closest to 2-Propionylpyrrole by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.
| Material | FEMA | Similarity | Occurrence |
|---|---|---|---|
| Methyl 2-pyrrolyl ketone | 3202 | 84% | In nature |
| Skatole | 3019 | 79% | In nature |
| Pyrrole | 3386 | 69% | In nature |
| Indole | 2593 | 68% | In nature |
| 4-Amino-5,6-dimethylthieno[2,3-d]pyrimidin-2(1H)-one | 4669 | 63% | Not determined |
More ketones in this index
2-Acetylpyridine · 1-Methyl-2-acetylpyrrole · 3-(3-Hydroxy-4-methoxyphenyl)-1-(2,4,6-trihydroxyphenyl) propan-1-one · 4-Acetyl-6-t-butyl-1,1-dimethylindan · d-Carvone · alpha-Ionone
2-Propionylpyrrole FAQ
Is 2-Propionylpyrrole on the FEMA GRAS list?
It is. FEMA number 3614 covers 2-Propionylpyrrole. It is also codified at 21 CFR 172.515.
What is the FEMA number for 2-Propionylpyrrole?
The FEMA number for 2-Propionylpyrrole is 3614 and its CAS registry number is 1073-26-3. FEMA files it in the nutty flavor category.
Is 2-Propionylpyrrole approved in the EU?
2-Propionylpyrrole is on the EU Union List of flavouring substances as FL 14.068 (Annex I Part A) under Regulation 1334/2008.
Has JECFA evaluated 2-Propionylpyrrole?
Yes. JECFA number 1319.
What is 2-Propionylpyrrole used for?
2-Propionylpyrrole is described as nutty, roasted, chocolate, earthy, sweet. On the palate it is nutty, sweet, creamy. It shows up in baked goods, confectionery, snacks and dairy.
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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as 2-PROPIONYLPYRROLE under CAS 1073-26-3 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.