Flavor ingredient regulatory record
2-Propionylthiazole
2-Propionylthiazole is a thiazole in the savory family, FEMA GRAS under FEMA number 3611 (CAS 43039-98-1). Its odor is nutty, roasted, popcorn, savory, earthy.
- FEMA
- 3611
- CAS
- 43039-98-1
- JECFA
- 1042
- EU FL
- 15.027
- Formula
- C6H7NOS
GRAS status: FEMA GRAS, publication 12. Recorded by FDA in the Substances Added to Food inventory under CAS 43039-98-1.
Structure
Identity
Also known as: 1-Propanone, 1-(2-thiazolyl)-, 1-(2-Thiazolyl)-1-propanone, 1-(1,3-Thiazol-2-yl)propan-1-one, 2-propionyl thiazole, 1-propanone, 1-(2-thiazolyl)-, thiazole, 2-propionyl-, ethyl 2-thiazolyl ketone, 1-(2-thiazolyl)-1-propanone, propionylthiazole, 2-, 2-propionylthiazole [fhfi], 1-(thiazol-2-yl)propan-1-one, 1-(1,3-thiazol-2-yl)propan-1-one.
Can 2-Propionylthiazole be labeled natural?
The process decides for 2-Propionylthiazole. It occurs in nature, so a natural-source, natural-process material is natural flavor in the US and synthetic 2-Propionylthiazole is artificial. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic 2-Propionylthiazole identical-to-natural.
- United States
- Natural or artificial, by process
- European Union and UK
- Natural only from natural material
- Mercosur and Mexico
- Natural or identical-to-natural
How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.
Regulatory status, with citations
United States
2-Propionylthiazole is FEMA GRAS under FEMA number 3611. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
Listed on the Union List of flavouring substances as FL 15.027, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.
JECFA (WHO / FAO)
JECFA number 1042, evaluated at the 59th meeting in 2002. no safety concern at current levels of intake when used as a flavouring agent.
Other US flags
Not on the California Proposition 65 list.
Odor and taste
Odor: Nutty, roasted, popcorn, savory, earthy.
Taste: Savory, umami, slightly nutty.
Where it is used
2-Propionylthiazole is used in snack foods, seasonings, savory sauces and meat products, typically as a savory note.
Structurally similar flavor ingredients
Flavor ingredients with a GRAS determination closest to 2-Propionylthiazole by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.
| Material | FEMA | Similarity | Occurrence |
|---|---|---|---|
| 2-Acetylthiazole | 3328 | 78% | In nature |
| 5-Ethyl-2-methylthiazole | 4388 | 72% | In nature |
| 2,4-Dimethyl-5-acetylthiazole | 3267 | 71% | In nature |
| S-Methyl thiofuroate | 3311 | 70% | In nature |
| 2-Isobutylthiazole | 3134 | 67% | In nature |
More thiazoles in this index
2-Ethyl-2,5-dihydro-4-methylthiazole · 2-Pentylthiazole · 2,4-Dimethyl-5-acetylthiazole · 5-Ethyl-2-methylthiazole · 2,4-Dimethyl-5-vinylthiazole · 2,4,5-Trimethylthiazole
2-Propionylthiazole FAQ
Is 2-Propionylthiazole on the FEMA GRAS list?
It is. FEMA number 3611 covers 2-Propionylthiazole. The Code of Federal Regulations lists it at 21 CFR 172.515.
What is the FEMA number for 2-Propionylthiazole?
The FEMA number for 2-Propionylthiazole is 3611 and its CAS registry number is 43039-98-1. Its flavor category is savory.
What is 2-Propionylthiazole used for?
2-Propionylthiazole is described as nutty, roasted, popcorn, savory, earthy. On the palate it is savory, umami, slightly nutty. It shows up in snack foods, seasonings, savory sauces and meat products.
What did JECFA conclude about 2-Propionylthiazole?
JECFA evaluated 2-Propionylthiazole at the 59th meeting in 2002 under JECFA number 1042. The panel concluded: no safety concern at current levels of intake when used as a flavouring agent.
Is 2-Propionylthiazole approved in the EU?
Yes. FL 15.027 is the Union List entry for 2-Propionylthiazole, annex I Part A, under Regulation 1334/2008, and the UK keeps the same list.
Is 2-Propionylthiazole natural or artificial?
Nature makes 2-Propionylthiazole, which is why the US label turns on process. A natural route gives natural flavor; synthesis gives artificial 2-Propionylthiazole, same molecule. The EU and UK grant the natural claim only to that natural route; Mercosur and Mexico call synthetic material identical-to-natural.
Ingredient lookup
Check an ingredient
Start typing to search the ingredient corpus.
Or browse every ingredient page, A to Z.
Guides: What Is FEMA GRAS? · Natural vs artificial · Filing a GRAS notification
Check 2-Propionylthiazole in a formula
Screened against FEMA GRAS, 21 CFR and EU rules as you build. Free to start.
Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as 2-PROPIONYLTHIAZOLE under CAS 43039-98-1 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.