Flavor ingredient regulatory record

4-Hydroxybenzaldehyde

4-Hydroxybenzaldehyde is an aldehyde in the floral family, FEMA GRAS under FEMA number 3984 (CAS 123-08-0). Its odor is sweet, floral, almond, cherry, nutty.

FEMA
3984
CAS
123-08-0
JECFA
956
EU FL
05.047
Formula
C7H6O2
EC
204-599-1

GRAS status: FEMA GRAS, publication 20. Recorded by FDA in the Substances Added to Food inventory under CAS 123-08-0.

Structure

2D structure of 4-Hydroxybenzaldehyde
Structure of 4-Hydroxybenzaldehyde, C7H6O2. Drawn from the canonical SMILES.

Identity

IUPAC name 4-hydroxybenzaldehyde
CAS number 123-08-0
FEMA number 3984
Molecular formula C7H6O2
Molecular weight 122.12 g/mol
SMILES O=Cc1ccc(O)cc1
InChIKey RGHHSNMVTDWUBI-UHFFFAOYSA-N
PubChem CID 126
EC number 204-599-1
FDA UNII O1738X3Y38
EPA DTXSID DTXSID8059552
Chemical class Aldehyde
Boiling point 109 °C
Flash point 38 °C

Also known as: Benzaldehyde, 4-hydroxy-, Benzaldehyde, p-hydroxy-, 4-Formylphenol, p-Formylphenol, p-Oxybenzaldehyde, Parahydroxybenzaldehyde, p-Hydroxybenzaldehyde, NSC 2127, p-hydroxybenzaldehyde, 4-formylphenol, p-formylphenol, benzaldehyde, 4-hydroxy-.

Can 4-Hydroxybenzaldehyde be labeled natural?

4-Hydroxybenzaldehyde occurs in nature, so the label depends on the route: 4-Hydroxybenzaldehyde won from a natural source by a physical, enzymatic or microbiological process is natural flavor in the United States, and synthesized 4-Hydroxybenzaldehyde is artificial. The EU and UK grant the natural claim only to that natural route; Mercosur and Mexico call synthetic material identical-to-natural.

United States
Natural or artificial, by process
European Union and UK
Natural only from natural material
Mercosur and Mexico
Natural or identical-to-natural

How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.

Regulatory status, with citations

United States

4-Hydroxybenzaldehyde is FEMA GRAS under FEMA number 3984. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 05.047, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.

JECFA (WHO / FAO)

JECFA number 956, evaluated at the 57th meeting in 2001. no safety concern at current levels of intake.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

TSCA Inventory status

A flavor ingredient is also an industrial chemical. 4-Hydroxybenzaldehyde appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 123-08-0, where EPA names it Benzaldehyde, 4-hydroxy-.

Active in US commerce

EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.

EPA publishes no regulatory flags on this listing. What the flags mean.

From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.

Odor and taste

Odor: Sweet, floral, almond, cherry, nutty.

Taste: Sweet, slightly bitter, nutty.

Where it is used

4-Hydroxybenzaldehyde is used in beverage, confection, bakery, flavoring and cosmetics, typically as a floral note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to 4-Hydroxybenzaldehyde by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
Benzaldehyde212780%In nature
Piperonal291178%In nature
2-Hydroxy-4-methylbenzaldehyde369778%In nature
4-Hydroxyacetophenone433073%In nature
o-trans-Coumaric acid470068%In nature

More aldehydes in this index

Hydroxycitronellal · 2-Hydroxy-4-methoxybenzaldehyde · p-Methoxybenzaldehyde · Veratraldehyde · Anisaldehyde propyleneglycol acetal · Piperonal propyleneglycol acetal

4-Hydroxybenzaldehyde FAQ

Is 4-Hydroxybenzaldehyde FEMA GRAS?

Yes. The FEMA Expert Panel lists 4-Hydroxybenzaldehyde as GRAS under FEMA number 3984. It is also codified at 21 CFR 172.515.

What are the FEMA and CAS numbers for 4-Hydroxybenzaldehyde?

4-Hydroxybenzaldehyde is FEMA 3984, CAS 123-08-0. FEMA files it in the floral flavor category.

Does 4-Hydroxybenzaldehyde count as natural in the US and the EU?

Since 4-Hydroxybenzaldehyde is found in nature, US labeling follows how it was obtained: natural flavor from a natural source and a natural process, artificial when 4-Hydroxybenzaldehyde is synthesized. The EU and UK grant the natural claim only to that natural route; Mercosur and Mexico call synthetic material identical-to-natural.

Is 4-Hydroxybenzaldehyde on the EU Union List?

4-Hydroxybenzaldehyde is on the EU Union List of flavouring substances as FL 05.047 (Annex I Part A) under Regulation 1334/2008.

Has JECFA evaluated 4-Hydroxybenzaldehyde?

Yes. JECFA number 956, evaluated at the 57th meeting in 2001. Conclusion: no safety concern at current levels of intake.

How is 4-Hydroxybenzaldehyde described, and where does it show up?

Flavorists describe 4-Hydroxybenzaldehyde as sweet, floral, almond, cherry, nutty. On the palate it is sweet, slightly bitter, nutty. It is used in beverage, confection, bakery, flavoring and cosmetics.

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as 4-HYDROXYBENZALDEHYDE under CAS 123-08-0 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.