Flavor ingredient regulatory record

Phenylacetaldehyde

Phenylacetaldehyde is an aldehyde in the floral family, FEMA GRAS under FEMA number 2874 (CAS 122-78-1). Its odor is floral, rose, honey, sweet.

FEMA
2874
CAS
122-78-1
JECFA
1002
EU FL
05.030
Formula
C8H8O
EC
204-574-5

GRAS status: FEMA GRAS, publication 3. Recorded by FDA in the Substances Added to Food inventory under CAS 122-78-1.

Structure

2D structure of Phenylacetaldehyde
Structure of Phenylacetaldehyde, C8H8O. Drawn from the canonical SMILES.

Identity

IUPAC name 2-phenylacetaldehyde
CAS number 122-78-1
FEMA number 2874
Molecular formula C8H8O
Molecular weight 120.15 g/mol
SMILES O=CCc1ccccc1
InChIKey DTUQWGWMVIHBKE-UHFFFAOYSA-N
PubChem CID 998
EC number 204-574-5
FDA UNII U8J5PLW9MR
EPA DTXSID DTXSID3021483
Chemical class Aldehyde
Boiling point 195 °C
Flash point 83 °C

Also known as: Benzeneacetaldehyde, Acetaldehyde, phenyl-, Phenylacetic aldehyde, α-Tolualdehyde, α-Toluic aldehyde, 2-Phenylethanal, Phenylethanal, α-Phenylacetaldehyde, Phenacetaldehyde, NSC 406309, Hyacinthin, Benzylcarboxaldehyde.

Can Phenylacetaldehyde be labeled natural?

Since phenylacetaldehyde is found in nature, US labeling follows how it was obtained: natural flavor from a natural source and a natural process, artificial when phenylacetaldehyde is synthesized. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.

United States
Natural or artificial, by process
European Union and UK
Natural only from natural material
Mercosur and Mexico
Natural or identical-to-natural

How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.

Regulatory status, with citations

United States

Phenylacetaldehyde is FEMA GRAS under FEMA number 2874. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 05.030, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.

JECFA (WHO / FAO)

JECFA number 1002, evaluated at the 59th meeting in 2002. No safety concern at current levels of intake when used as a flavouring agent.

JECFA monograph

Other US flags

Not on the California Proposition 65 list. Listed on the EPA TSCA inventory.

TSCA Inventory status

A flavor ingredient is also an industrial chemical. Phenylacetaldehyde appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 122-78-1, where EPA names it Benzeneacetaldehyde.

Active in US commerce

EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.

EPA publishes no regulatory flags on this listing. What the flags mean.

From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.

Odor and taste

Odor: Floral, rose, honey, sweet.

Taste: Floral, honey, slightly chocolate.

Where it is used

Phenylacetaldehyde is used in rose, honey and chocolate, typically as a floral note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to Phenylacetaldehyde by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
2-Phenylpropionaldehyde288686%In nature
2-Hexenal256079%In nature
(E,E)-2,4-Hexadienal342979%In nature
Phenethyl alcohol285879%In nature
3-Hexenal392378%In nature

More aldehydes in this index

4-Hydroxybenzaldehyde · o-Anisaldehyde · 2-Hydroxy-4-methoxybenzaldehyde · Hydroxycitronellal · Anisaldehyde propyleneglycol acetal · 4-Hydroxy-3,5-dimethoxybenzaldehyde

Phenylacetaldehyde FAQ

Is phenylacetaldehyde FEMA GRAS?

Yes. The FEMA Expert Panel lists phenylacetaldehyde as GRAS under FEMA number 2874. It is also codified at 21 CFR 172.515.

What are the FEMA and CAS numbers for phenylacetaldehyde?

Phenylacetaldehyde is FEMA 2874, CAS 122-78-1. FEMA files it in the floral flavor category.

Does phenylacetaldehyde count as natural in the US and the EU?

Phenylacetaldehyde occurs in nature, so the label depends on the route: phenylacetaldehyde won from a natural source by a physical, enzymatic or microbiological process is natural flavor in the United States, and synthesized phenylacetaldehyde is artificial. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic phenylacetaldehyde identical-to-natural.

Is phenylacetaldehyde on the EU Union List?

Phenylacetaldehyde is on the EU Union List of flavouring substances as FL 05.030 (Annex I Part A) under Regulation 1334/2008.

Has JECFA evaluated phenylacetaldehyde?

Yes. JECFA number 1002, evaluated at the 59th meeting in 2002. Conclusion: No safety concern at current levels of intake when used as a flavouring agent.

How is phenylacetaldehyde described, and where does it show up?

Flavorists describe phenylacetaldehyde as floral, rose, honey, sweet. On the palate it is floral, honey, slightly chocolate. It is used in rose, honey and chocolate.

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as PHENYLACETALDEHYDE under CAS 122-78-1 and carries its FEMA number, its JECFA flavor number and its 21 CFR citations. The inventory is searchable at FDA. FDA records its technical effect as flavor enhancer, flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.