Flavor ingredient regulatory record

p-Methoxybenzaldehyde

p-Methoxybenzaldehyde is an aldehyde in the floral family, FEMA GRAS under FEMA number 2670 (CAS 123-11-5). Its odor is sweet, floral, almond, cherry, aromatic.

FEMA
2670
CAS
123-11-5
JECFA
878
EU FL
05.015
Formula
C8H8O2
EC
204-602-6

GRAS status: FEMA GRAS, publication 3. Recorded by FDA in the Substances Added to Food inventory under CAS 123-11-5.

Structure

2D structure of p-Methoxybenzaldehyde
Structure of p-Methoxybenzaldehyde, C8H8O2. Drawn from the canonical SMILES.

Identity

IUPAC name 4-methoxybenzaldehyde
CAS number 123-11-5
FEMA number 2670
Molecular formula C8H8O2
Molecular weight 136.15 g/mol
SMILES COc1ccc(C=O)cc1
InChIKey ZRSNZINYAWTAHE-UHFFFAOYSA-N
PubChem CID 31244
EC number 204-602-6
FDA UNII 9PA5V6656V
EPA DTXSID DTXSID2026997
Chemical class Aldehyde
Boiling point 250 °C
Flash point 116 °C

Also known as: Benzaldehyde, 4-methoxy-, p-Anisaldehyde, 4-Methoxybenzaldehyde, Anisic aldehyde, Crategine, Anisaldehyde, Aubepine, p-Anisic aldehyde, 4-Anisaldehyde, p-Formylanisole, Obepin, NSC 5590.

Can p-Methoxybenzaldehyde be labeled natural?

Since p-Methoxybenzaldehyde is found in nature, US labeling follows how it was obtained: natural flavor from a natural source and a natural process, artificial when p-Methoxybenzaldehyde is synthesized. In the EU and UK the natural claim likewise needs the natural route, while Mercosur and Mexico keep a third class, identical-to-natural, for the synthetic material.

United States
Natural or artificial, by process
European Union and UK
Natural only from natural material
Mercosur and Mexico
Natural or identical-to-natural

How each market defines the classes: natural vs artificial flavor under 21 CFR 101.22.

Regulatory status, with citations

United States

p-Methoxybenzaldehyde is FEMA GRAS under FEMA number 2670. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 05.015, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.

JECFA (WHO / FAO)

JECFA number 878, evaluated at the 57th meeting in 2001. No safety concern at current levels of intake when used as a flavouring agent.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

TSCA Inventory status

A flavor ingredient is also an industrial chemical. p-Methoxybenzaldehyde appears on the EPA Toxic Substances Control Act Chemical Substance Inventory under CAS 123-11-5, where EPA names it Benzaldehyde, 4-methoxy-.

Active in US commerce

EPA designates this substance active, so no Notice of Activity Form B is required before manufacturing. What active and inactive mean.

EPA publishes no regulatory flags on this listing. What the flags mean.

From the EPA non-confidential TSCA Inventory, July 2026 release. EPA also maintains a confidential portion it does not publish. Search the Inventory by CAS number.

Odor and taste

Odor: Sweet, floral, almond, cherry, aromatic.

Taste: Sweet, slightly bitter, nutty.

Where it is used

p-Methoxybenzaldehyde is used in beverage, confection, bakery, flavoring and cosmetics, typically as a floral note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to p-Methoxybenzaldehyde by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
2-Hydroxy-4-methoxybenzaldehyde443585%In nature
Anisyl alcohol209984%In nature
Cuminaldehyde234183%In nature
4-Ethylbenzaldehyde375683%In nature
Veratraldehyde310976%In nature

More aldehydes in this index

Piperonal propyleneglycol acetal · 2-Hydroxy-4-methoxybenzaldehyde · 4-Hydroxy-3,5-dimethoxybenzaldehyde · Anisaldehyde propyleneglycol acetal · Hydroxycitronellal · Veratraldehyde

p-Methoxybenzaldehyde FAQ

Is p-Methoxybenzaldehyde FEMA GRAS?

Yes. The FEMA Expert Panel lists p-Methoxybenzaldehyde as GRAS under FEMA number 2670. It is also codified at 21 CFR 172.515.

What are the FEMA and CAS numbers for p-Methoxybenzaldehyde?

p-Methoxybenzaldehyde is FEMA 2670, CAS 123-11-5. FEMA files it in the floral flavor category.

Does p-Methoxybenzaldehyde count as natural in the US and the EU?

p-Methoxybenzaldehyde occurs in nature, so the label depends on the route: p-Methoxybenzaldehyde won from a natural source by a physical, enzymatic or microbiological process is natural flavor in the United States, and synthesized p-Methoxybenzaldehyde is artificial. The EU and UK follow the same logic without a middle class; Mercosur and Mexico label synthetic p-Methoxybenzaldehyde identical-to-natural.

Is p-Methoxybenzaldehyde on the EU Union List?

p-Methoxybenzaldehyde is on the EU Union List of flavouring substances as FL 05.015 (Annex I Part A) under Regulation 1334/2008.

Has JECFA evaluated p-Methoxybenzaldehyde?

Yes. JECFA number 878, evaluated at the 57th meeting in 2001. Conclusion: No safety concern at current levels of intake when used as a flavouring agent.

How is p-Methoxybenzaldehyde described, and where does it show up?

Flavorists describe p-Methoxybenzaldehyde as sweet, floral, almond, cherry, aromatic. On the palate it is sweet, slightly bitter, nutty. It is used in beverage, confection, bakery, flavoring and cosmetics.

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as P-METHOXYBENZALDEHYDE under CAS 123-11-5 and carries its FEMA number, its JECFA flavor number and its 21 CFR citations. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.