Flavor ingredient regulatory record
(+/-) 4-Methyl-2-propyl-1,3-oxathiane
(+/-) 4-Methyl-2-propyl-1,3-oxathiane is a thiol in the fruity family, FEMA GRAS under FEMA number 4677 (CAS 1064678-08-5). Its odor is sweet, fruity, tropical, citrus, herbal.
- FEMA
- 4677
- CAS
- 1064678-08-5
- JECFA
- 2089
- EU FL
- 16.122
GRAS status: FEMA GRAS, publication 25. Recorded by FDA in the Substances Added to Food inventory under CAS 1064678-08-5.
Structure
Under review
The structure for (+/-) 4-Methyl-2-propyl-1,3-oxathiane is still under identity review, so no drawing is shown until the record is confirmed.
Identity
Also known as: 4-methyl-2-propyl-1,3-oxathiane, 1,3-oxathiane, 4-methyl-2-propyl-.
Can (+/-) 4-Methyl-2-propyl-1,3-oxathiane be labeled natural?
Nature occurrence: Not yet found in nature (provisional).
Nature occurrence has not been settled for this substance, so the natural or artificial class is not stated here. The FEMA GRAS status does not depend on it.
Regulatory status, with citations
United States
(+/-) 4-Methyl-2-propyl-1,3-oxathiane is FEMA GRAS under FEMA number 4677. It is cited in the Code of Federal Regulations at 21 CFR 172.515.
European Union and United Kingdom
Listed on the Union List of flavouring substances as FL 16.122, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.
JECFA (WHO / FAO)
JECFA number 2089, evaluated at the 76th meeting in 2012. No safety concern at current levels of intake when used as a flavouring agent.
Other US flags
Not on the California Proposition 65 list.
Odor and taste
Odor: Sweet, fruity, tropical, citrus, herbal.
Where it is used
(+/-) 4-Methyl-2-propyl-1,3-oxathiane is used in beverage, confection, fruit flavors and snacks, typically as a fruity note.
Structurally similar flavor ingredients
Flavor ingredients with a GRAS determination closest to (+/-) 4-Methyl-2-propyl-1,3-oxathiane by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.
| Material | FEMA | Similarity | Occurrence |
|---|---|---|---|
| 2-Methyl-4-propyl-1,3-oxathiane | 3578 | 94% | In nature |
| delta-Octalactone | 3214 | 64% | Not determined |
| (+/-)-cis- and trans-2-Pentyl-4-propyl-1,3-oxathiane | 4499 | 54% | Not determined |
| 2,5-Dimethyl-3-thioacetoxy-tetrahydrofuran, cis and trans isomers | 3972 | 52% | Not determined |
More thiols in this index
2-Methyl-3-furanthiol · (+/-)-cis- and trans-2-Pentyl-4-propyl-1,3-oxathiane · 3-Mercapto-2-methylpentanal · Triethylthialdine · (+/-)-2,8-Epithio-cis-p-menthane · 2,5-Dimethyl-3-tetrahydrofuranthiol, cis and trans isomers
(+/-) 4-Methyl-2-propyl-1,3-oxathiane FAQ
Is (+/-) 4-Methyl-2-propyl-1,3-oxathiane FEMA GRAS?
Yes. The FEMA Expert Panel lists (+/-) 4-Methyl-2-propyl-1,3-oxathiane as GRAS under FEMA number 4677. The Code of Federal Regulations lists it at 21 CFR 172.515.
What are the FEMA and CAS numbers for (+/-) 4-Methyl-2-propyl-1,3-oxathiane?
(+/-) 4-Methyl-2-propyl-1,3-oxathiane is FEMA 4677, CAS 1064678-08-5. Its flavor category is fruity.
How is (+/-) 4-Methyl-2-propyl-1,3-oxathiane described, and where does it show up?
Flavorists describe (+/-) 4-Methyl-2-propyl-1,3-oxathiane as sweet, fruity, tropical, citrus, herbal. It is used in beverage, confection, fruit flavors and snacks.
What did JECFA conclude about (+/-) 4-Methyl-2-propyl-1,3-oxathiane?
JECFA evaluated (+/-) 4-Methyl-2-propyl-1,3-oxathiane at the 76th meeting in 2012 under JECFA number 2089. The panel concluded: No safety concern at current levels of intake when used as a flavouring agent.
Is (+/-) 4-Methyl-2-propyl-1,3-oxathiane on the EU Union List?
Yes. FL 16.122 is the Union List entry for (+/-) 4-Methyl-2-propyl-1,3-oxathiane, annex I Part A, under Regulation 1334/2008, and the UK keeps the same list.
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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as (+/-)-4-METHYL-2-PROPYL-1,3-OXATHIANE under CAS 1064678-08-5 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.
A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.
Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.
About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.