Flavor ingredient regulatory record

(+/-)-cis- and trans-2-Pentyl-4-propyl-1,3-oxathiane

(+/-)-cis- and trans-2-Pentyl-4-propyl-1,3-oxathiane is a thiol in the fruity family, FEMA GRAS under FEMA number 4499 (CAS 59323-81-8). Its odor is sweet, fruity, tropical, citrus, green.

FEMA
4499
CAS
59323-81-8
JECFA
1943
EU FL
16.114

GRAS status: FEMA GRAS, publication 24. Recorded by FDA in the Substances Added to Food inventory under CAS 59323-81-8.

Structure

Under review

The structure for (+/-)-cis- and trans-2-Pentyl-4-propyl-1,3-oxathiane is still under identity review, so no drawing is shown until the record is confirmed.

Identity

CAS number 59323-81-8
FEMA number 4499
FDA UNII 5035RP211X
EPA DTXSID DTXSID001019793
Chemical class Thiol

Also known as: 2-pentyl-4-propyl-1,3-oxathiane.

Can (+/-)-cis- and trans-2-Pentyl-4-propyl-1,3-oxathiane be labeled natural?

Nature occurrence: Not yet found in nature (provisional).

Nature occurrence has not been settled for this substance, so the natural or artificial class is not stated here. The FEMA GRAS status does not depend on it.

Regulatory status, with citations

United States

(+/-)-cis- and trans-2-Pentyl-4-propyl-1,3-oxathiane is FEMA GRAS under FEMA number 4499. It is cited in the Code of Federal Regulations at 21 CFR 172.515.

21 CFR 172.515

European Union and United Kingdom

Listed on the Union List of flavouring substances as FL 16.114, Annex I Part A under Regulation (EC) 1334/2008, evaluation status approved (EFSA). The UK retains the same list.

JECFA (WHO / FAO)

JECFA number 1943, evaluated at the 73rd meeting in 2010.

JECFA monograph

Other US flags

Not on the California Proposition 65 list.

Odor and taste

Odor: Sweet, fruity, tropical, citrus, green.

Taste: Sweet, fruity, slightly acidic.

Where it is used

(+/-)-cis- and trans-2-Pentyl-4-propyl-1,3-oxathiane is used in beverage, confection, fruit flavors, bakery and dairy, typically as a fruity note.

Structurally similar flavor ingredients

Flavor ingredients with a GRAS determination closest to (+/-)-cis- and trans-2-Pentyl-4-propyl-1,3-oxathiane by structure. Whether one can replace it is a sensory and regulatory call; the reformulation tool works that through.

MaterialFEMASimilarityOccurrence
Acetaldehyde 1,3-octadiol acetal437679%Not determined
3-(Methylthio)-decanal473468%Not determined
delta-Dodecalactone240167%In nature

More thiols in this index

(+/-) 4-Methyl-2-propyl-1,3-oxathiane · 2-Hexylthiophene · S-Methyl 3-methylbutanethioate · 2-Methyl-3-furanthiol · (S)-1-Methoxy-3-heptanthiol · 3-Mercaptohexanal

(+/-)-cis- and trans-2-Pentyl-4-propyl-1,3-oxathiane FAQ

Is (+/-)-cis- and trans-2-Pentyl-4-propyl-1,3-oxathiane on the FEMA GRAS list?

It is. FEMA number 4499 covers (+/-)-cis- and trans-2-Pentyl-4-propyl-1,3-oxathiane. The Code of Federal Regulations lists it at 21 CFR 172.515.

What is the FEMA number for (+/-)-cis- and trans-2-Pentyl-4-propyl-1,3-oxathiane?

The FEMA number for (+/-)-cis- and trans-2-Pentyl-4-propyl-1,3-oxathiane is 4499 and its CAS registry number is 59323-81-8. Its flavor category is fruity.

What is (+/-)-cis- and trans-2-Pentyl-4-propyl-1,3-oxathiane used for?

(+/-)-cis- and trans-2-Pentyl-4-propyl-1,3-oxathiane is described as sweet, fruity, tropical, citrus, green. On the palate it is sweet, fruity, slightly acidic. It shows up in beverage, confection, fruit flavors, bakery and dairy.

What did JECFA conclude about (+/-)-cis- and trans-2-Pentyl-4-propyl-1,3-oxathiane?

JECFA evaluated (+/-)-cis- and trans-2-Pentyl-4-propyl-1,3-oxathiane at the 73rd meeting in 2010 under JECFA number 1943.

Is (+/-)-cis- and trans-2-Pentyl-4-propyl-1,3-oxathiane approved in the EU?

Yes. FL 16.114 is the Union List entry for (+/-)-cis- and trans-2-Pentyl-4-propyl-1,3-oxathiane, annex I Part A, under Regulation 1334/2008, and the UK keeps the same list.

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Sources and attribution. The identity and regulatory facts on this page are taken from the FDA Substances Added to Food inventory, a US government record, which lists this substance as (+/-)CIS- AND TRANS-2-PENTYL-4-PROPYL-1,3-OXATHIANE under CAS 59323-81-8 and carries its FEMA number, its JECFA flavor number. The inventory is searchable at FDA. FDA records its technical effect as flavoring agent or adjuvant.

A FEMA GRAS conclusion is reached by the Expert Panel of the Flavor and Extract Manufacturers Association of the United States, and the FEMA number names that conclusion. FEMA publishes its own entry for this substance in the FEMA Flavor Library, which is the authoritative record of what the Panel decided and is worth reading alongside this page.

Ambrose Compliance is not affiliated with, endorsed by, or sponsored by FEMA. FEMA and FEMA GRAS are used here as identifiers for a published regulatory determination, not as marks of any relationship between FEMA and Ambrose.

About this page. Facts come from the FDA Substances Added to Food inventory, the Code of Federal Regulations, the EPA TSCA Inventory, the EU Union List, JECFA and the Ambrose database, with FEMA's published determination cited where it applies; parts of the text are written by Ambrose AI, which can make mistakes. Check the cited source before relying on anything here. This is not regulatory or legal advice.